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Murcko scaffold

2-(Pyrrolidin-2-yl)pyrimidine scaffold

58 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
58
With full pages
5
Scaffold SMILES

c1cnc(C2CCCN2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyrrolidin-2-yl)pyrimidine page
Murcko scaffold c1cnc(C2CCCN2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 58 of 58 chemicals

2-(1-Methylpyrrolidin-2-yl)pyrimidine-4-carboxylic acid chemical structure, C10H13N3O2, CAS 2107487-42-1
2-(1-Methylpyrrolidin-2-yl)pyrimidine-4-carboxylic acid
CAS 2107487-42-1C10H13N3O2
4-Methyl-2-(1-methylpyrrolidin-2-yl)pyrimidine-5-carboxylic acid chemical structure, C11H15N3O2, CAS 2137763-99-4
4-Methyl-2-(1-methylpyrrolidin-2-yl)pyrimidine-5-carboxylic acid
CAS 2137763-99-4C11H15N3O2
5-Ethenyl-2-(pyrrolidin-2-yl)pyrimidine chemical structure, C10H13N3, CAS 2137885-49-3
5-Ethenyl-2-(pyrrolidin-2-yl)pyrimidine
CAS 2137885-49-3C10H13N3
2-(1-Nitrosopyrrolidin-2-yl)pyrimidine-5-carboxylic acid chemical structure, C9H10N4O3, CAS 2624139-74-6
2-(1-Nitrosopyrrolidin-2-yl)pyrimidine-5-carboxylic acid
CAS 2624139-74-6C9H10N4O3
2-[1-(2,2,2-Trifluoroacetyl)pyrrolidin-2-yl]pyrimidine-5-carboxylic acid chemical structure, C11H10F3N3O3, CAS 2680715-13-1
2-[1-(2,2,2-Trifluoroacetyl)pyrrolidin-2-yl]pyrimidine-5-carboxylic acid
CAS 2680715-13-1C11H10F3N3O3
2-(1-Acetylpyrrolidin-2-yl)pyrimidine-5-carboxylic acid chemical structure, C11H13N3O3, CAS 2680749-77-1
2-(1-Acetylpyrrolidin-2-yl)pyrimidine-5-carboxylic acid
CAS 2680749-77-1C11H13N3O3
2-{1-[(Prop-2-en-1-yloxy)carbonyl]pyrrolidin-2-yl}pyrimidine-5-carboxylic acid chemical structure, C13H15N3O4, CAS 2680688-58-6
2-{1-[(Prop-2-en-1-yloxy)carbonyl]pyrrolidin-2-yl}pyrimidine-5-carboxylic acid
CAS 2680688-58-6C13H15N3O4
tert-Butyl (R)-2-(pyrimidin-2-yl)pyrrolidine-1-carboxylate chemical structure, C13H19N3O2, CAS 1029650-58-5
tert-Butyl (R)-2-(pyrimidin-2-yl)pyrrolidine-1-carboxylate
CAS 1029650-58-5C13H19N3O2
5-Fluoro-2-(pyrrolidin-2-yl)pyrimidine hydrochloride chemical structure, C8H11ClFN3, CAS 3017194-22-5
5-Fluoro-2-(pyrrolidin-2-yl)pyrimidine hydrochloride
CAS 3017194-22-5C8H11ClFN3
tert-Butyl 2-(5-fluoropyrimidin-2-yl)pyrrolidine-1-carboxylate chemical structure, C13H18FN3O2, CAS 3017211-25-2
tert-Butyl 2-(5-fluoropyrimidin-2-yl)pyrrolidine-1-carboxylate
CAS 3017211-25-2C13H18FN3O2