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Murcko scaffold

2-(1H-Pyrazol-4-yl)pyridine scaffold

167 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 167
With full pages: 6

Scaffold SMILES

c1ccc(-c2cn[nH]c2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-(1H-Pyrazol-4-yl)pyridine page

Murcko scaffold c1ccc(-c2cn[nH]c2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 167 of 167 chemicals

6-(1-Methylpyrazol-4-yl)pyridin-2-amine, dihydrochloride chemical structure, C9H12Cl2N4, CAS 2580211-02-3

6-(1-Methylpyrazol-4-yl)pyridin-2-amine, dihydrochloride

CAS 2580211-02-3C₉H₁₂Cl₂N₄

Methyl 3-amino-6-chloro-2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinecarboxylate chemical structure, C11H11ClN4O2, CAS 2648158-95-4

Methyl 3-amino-6-chloro-2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinecarboxylate

CAS 2648158-95-4C₁₁H₁₁ClN₄O₂

3-Methoxy-2-(1H-pyrazol-4-yl)pyridine chemical structure, C9H9N3O, CAS 2229166-25-8

3-Methoxy-2-(1H-pyrazol-4-yl)pyridine

CAS 2229166-25-8C₉H₉N₃O

4-Fluoro-2-(1H-pyrazol-4-yl)pyridine chemical structure, C8H6FN3, CAS 2229417-47-2

4-Fluoro-2-(1H-pyrazol-4-yl)pyridine

CAS 2229417-47-2C₈H₆FN₃

2-Methoxy-6-(1H-pyrazol-4-yl)-3-pyridinemethanol chemical structure, C10H11N3O2, CAS 2560576-52-3

2-Methoxy-6-(1H-pyrazol-4-yl)-3-pyridinemethanol

CAS 2560576-52-3C₁₀H₁₁N₃O₂

6-(1H-Pyrazol-4-yl)picolinaldehyde chemical structure, C9H7N3O, CAS 2984849-25-2

6-(1H-Pyrazol-4-yl)picolinaldehyde

CAS 2984849-25-2C₉H₇N₃O

2-Bromo-6-(1-methyl-1H-pyrazol-4-yl)pyridine-4-carboxylic acid chemical structure, C10H8BrN3O2, CAS 2138397-02-9

2-Bromo-6-(1-methyl-1H-pyrazol-4-yl)pyridine-4-carboxylic acid

CAS 2138397-02-9C₁₀H₈BrN₃O₂

Ethyl 5-amino-1-methyl-4-(pyridin-2-yl)-1H-pyrazole-3-carboxylate chemical structure, C12H14N4O2, CAS 2138381-53-8

Ethyl 5-amino-1-methyl-4-(pyridin-2-yl)-1H-pyrazole-3-carboxylate

CAS 2138381-53-8C₁₂H₁₄N₄O₂

Ethyl 5-amino-1-ethyl-4-(pyridin-2-yl)-1H-pyrazole-3-carboxylate chemical structure, C13H16N4O2, CAS 2138018-43-4

Ethyl 5-amino-1-ethyl-4-(pyridin-2-yl)-1H-pyrazole-3-carboxylate

CAS 2138018-43-4C₁₃H₁₆N₄O₂

5-Nitro-2-(1H-pyrazol-4-yl)pyridine chemical structure, C8H6N4O2, CAS 2228392-10-5

5-Nitro-2-(1H-pyrazol-4-yl)pyridine

CAS 2228392-10-5C₈H₆N₄O₂

2-(Propan-2-yloxy)-6-(1H-pyrazol-4-yl)pyridine chemical structure, C11H13N3O, CAS 2228789-49-7

2-(Propan-2-yloxy)-6-(1H-pyrazol-4-yl)pyridine

CAS 2228789-49-7C₁₁H₁₃N₃O

2-(1H-Pyrazol-4-yl)-3-(trifluoromethyl)pyridine chemical structure, C9H6F3N3, CAS 2228470-71-9

2-(1H-Pyrazol-4-yl)-3-(trifluoromethyl)pyridine

CAS 2228470-71-9C₉H₆F₃N₃

2-(1H-Pyrazol-4-yl)pyridine dihydrochloride chemical structure, C8H9Cl2N3, CAS 2742657-02-7

2-(1H-Pyrazol-4-yl)pyridine dihydrochloride

CAS 2742657-02-7C₈H₉Cl₂N₃

5-Bromo-3-nitro-2-(1H-pyrazol-4-yl)pyridine chemical structure, C8H5BrN4O2, CAS 2229554-18-9

5-Bromo-3-nitro-2-(1H-pyrazol-4-yl)pyridine

CAS 2229554-18-9C₈H₅BrN₄O₂

tert-Butyl N-[6-(5-chloro-1-methyl-1H-pyrazol-4-yl)pyridin-2-yl]carbamate chemical structure, C14H17ClN4O2, CAS 2680860-38-0

tert-Butyl N-[6-(5-chloro-1-methyl-1H-pyrazol-4-yl)pyridin-2-yl]carbamate

CAS 2680860-38-0C₁₄H₁₇ClN₄O₂

6-[3,5-Dimethyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrazol-4-yl]-3-pyridinamine chemical structure, C16H26N4OSi, CAS 2748752-43-2

6-[3,5-Dimethyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrazol-4-yl]-3-pyridinamine

CAS 2748752-43-2C₁₆H₂₆N₄OSi

6-[3,5-Dimethyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrazol-4-yl]-5-fluoro-3-pyridinamine chemical structure, C16H25FN4OSi, CAS 2755144-96-6

6-[3,5-Dimethyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-pyrazol-4-yl]-5-fluoro-3-pyridinamine

CAS 2755144-96-6C₁₆H₂₅FN₄OSi

6-(1-Methyl-1H-pyrazol-4-yl)picolinaldehyde chemical structure, C10H9N3O, CAS 2375230-60-5

6-(1-Methyl-1H-pyrazol-4-yl)picolinaldehyde

CAS 2375230-60-5C₁₀H₉N₃O

2-(1H-Pyrazol-4-yl)nicotinaldehyde chemical structure, C9H7N3O, CAS 3033401-99-6

2-(1H-Pyrazol-4-yl)nicotinaldehyde

CAS 3033401-99-6C₉H₇N₃O

6-(1-(tert-Butyl)-1H-pyrazol-4-yl)pyridin-3-amine chemical structure, C12H16N4, CAS 2287156-44-7

6-(1-(tert-Butyl)-1H-pyrazol-4-yl)pyridin-3-amine

CAS 2287156-44-7C₁₂H₁₆N₄

6-(1-Isopropyl-1H-pyrazol-4-yl)-5-methylpyridin-3-amine chemical structure, C12H16N4, CAS 1860612-50-5

6-(1-Isopropyl-1H-pyrazol-4-yl)-5-methylpyridin-3-amine

CAS 1860612-50-5C₁₂H₁₆N₄

6-(1-Isopropyl-1H-pyrazol-4-yl)-2-methylpyridin-3-amine chemical structure, C12H16N4, CAS 1852062-79-3

6-(1-Isopropyl-1H-pyrazol-4-yl)-2-methylpyridin-3-amine

CAS 1852062-79-3C₁₂H₁₆N₄

6-(1-Isobutyl-1H-pyrazol-4-yl)pyridin-2-amine chemical structure, C12H16N4, CAS 2162486-66-8

6-(1-Isobutyl-1H-pyrazol-4-yl)pyridin-2-amine

CAS 2162486-66-8C₁₂H₁₆N₄