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Murcko scaffold

2-(1H-Pyrazol-4-yl)pyridine scaffold

167 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
167
With full pages
6
Scaffold SMILES

c1ccc(-c2cn[nH]c2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Pyrazol-4-yl)pyridine page
Murcko scaffold c1ccc(-c2cn[nH]c2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 167 chemicals

3-Chloro-2-(1H-pyrazol-4-yl)-5-(trifluoromethyl)pyridine chemical structure, C9H5ClF3N3, CAS 246022-25-3
3-Chloro-2-(1H-pyrazol-4-yl)-5-(trifluoromethyl)pyridine
CAS 246022-25-3C9H5ClF3N3
4-(2-Pyridinyl)-1H-pyrazol-3-amine chemical structure, C8H8N4, CAS 493038-87-2
4-(2-Pyridinyl)-1H-pyrazol-3-amine
CAS 493038-87-2C8H8N4
1-{4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-1-yl}-1-ethanone chemical structure, C11H7ClF3N3O, CAS 251096-70-5
1-{4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-1-yl}-1-ethanone
CAS 251096-70-5C11H7ClF3N3O
1-{4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-1-yl}-2,2-dimethyl-1-propanone chemical structure, C14H13ClF3N3O, CAS 303150-33-6
1-{4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-1-yl}-2,2-dimethyl-1-propanone
CAS 303150-33-6C14H13ClF3N3O
N-Allyl-4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazole-1-carbothioamide chemical structure, C13H10ClF3N4S, CAS 306976-64-7
N-Allyl-4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazole-1-carbothioamide
CAS 306976-64-7C13H10ClF3N4S
1-{4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-1-yl}-2,2,2-trifluoro-1-ethanone chemical structure, C11H4ClF6N3O, CAS 306976-65-8
1-{4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-1-yl}-2,2,2-trifluoro-1-ethanone
CAS 306976-65-8C11H4ClF6N3O
2-(1H-Pyrazol-4-yl)pyridine chemical structure, C8H7N3, CAS 439106-75-9
2-(1H-Pyrazol-4-yl)pyridine
CAS 439106-75-9C8H7N3
6-(1-Methyl-1H-pyrazol-4-yl)pyridine-3-carboxylic acid chemical structure, C10H9N3O2, CAS 220461-82-5
6-(1-Methyl-1H-pyrazol-4-yl)pyridine-3-carboxylic acid
CAS 220461-82-5C10H9N3O2
4-(3-Methylpyridin-2-yl)-1H-pyrazole-3,5-diamine chemical structure, C9H11N5, CAS 62019-57-2
4-(3-Methylpyridin-2-yl)-1H-pyrazole-3,5-diamine
CAS 62019-57-2C9H11N5
1-Methyl-4-(pyridin-2-yl)-1H-pyrazol-5-amine chemical structure, C9H10N4, CAS 104909-45-7
1-Methyl-4-(pyridin-2-yl)-1H-pyrazol-5-amine
CAS 104909-45-7C9H10N4
4-(2-Pyridinyl)-1H-pyrazole-1-propanal chemical structure, C11H11N3O, CAS 439106-74-8
4-(2-Pyridinyl)-1H-pyrazole-1-propanal
CAS 439106-74-8C11H11N3O
5-Methyl-4-(pyridin-2-yl)-1H-pyrazol-3-amine chemical structure, C9H10N4, CAS 1160226-54-9
5-Methyl-4-(pyridin-2-yl)-1H-pyrazol-3-amine
CAS 1160226-54-9C9H10N4
2-(1H-Pyrazol-4-yl)-5-(trifluoromethyl)pyridine chemical structure, C9H6F3N3, CAS 1185578-37-3
2-(1H-Pyrazol-4-yl)-5-(trifluoromethyl)pyridine
CAS 1185578-37-3C9H6F3N3
2-Bromo-6-(1-methyl-1H-pyrazol-4-yl)pyridine chemical structure, C9H8BrN3, CAS 1093879-86-7
2-Bromo-6-(1-methyl-1H-pyrazol-4-yl)pyridine
CAS 1093879-86-7C9H8BrN3
4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-3-amine chemical structure, C9H6ClF3N4, CAS 1242267-93-1
4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-3-amine
CAS 1242267-93-1C9H6ClF3N4
4-(Pyridin-2-yl)-1H-pyrazole-5-carboxylic acid chemical structure, C9H7N3O2, CAS 1260765-26-1
4-(Pyridin-2-yl)-1H-pyrazole-5-carboxylic acid
CAS 1260765-26-1C9H7N3O2
4-(Pyridin-2-yl)-1H-pyrazole-3,5-diamine chemical structure, C8H9N5, CAS 887365-58-4
4-(Pyridin-2-yl)-1H-pyrazole-3,5-diamine
CAS 887365-58-4C8H9N5
2-Methyl-6-(1-methyl-1H-pyrazol-4-yl)pyridine chemical structure, C10H11N3, CAS 1855814-69-5
2-Methyl-6-(1-methyl-1H-pyrazol-4-yl)pyridine
CAS 1855814-69-5C10H11N3
6-(1-Methyl-1H-pyrazol-4-yl)pyridin-3-ol chemical structure, C9H9N3O, CAS 1256371-63-7
6-(1-Methyl-1H-pyrazol-4-yl)pyridin-3-ol
CAS 1256371-63-7C9H9N3O
6-(1-Methyl-1H-pyrazol-4-yl)pyridin-3-amine chemical structure, C9H10N4, CAS 1190380-28-9
6-(1-Methyl-1H-pyrazol-4-yl)pyridin-3-amine
CAS 1190380-28-9C9H10N4
4-Methyl-2-(1H-pyrazol-4-yl)pyridine chemical structure, C9H9N3, CAS 1928754-70-4
4-Methyl-2-(1H-pyrazol-4-yl)pyridine
CAS 1928754-70-4C9H9N3
2-Bromo-6-(1H-pyrazol-4-yl)pyridine chemical structure, C8H6BrN3, CAS 1093879-85-6
2-Bromo-6-(1H-pyrazol-4-yl)pyridine
CAS 1093879-85-6C8H6BrN3
(6-(1-Methyl-1H-pyrazol-4-yl)pyridin-3-yl)methanol chemical structure, C10H11N3O, CAS 1314141-32-6
(6-(1-Methyl-1H-pyrazol-4-yl)pyridin-3-yl)methanol
CAS 1314141-32-6C10H11N3O
5-(Bromomethyl)-2-(1-methylpyrazol-4-yl)pyridine chemical structure, C10H10BrN3, CAS 1314141-33-7
5-(Bromomethyl)-2-(1-methylpyrazol-4-yl)pyridine
CAS 1314141-33-7C10H10BrN3