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Murcko scaffold

2-Thiophen-2-yl-2,3-dihydro-1H-quinazolin-4-one scaffold

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
9
With full pages
5
Scaffold SMILES

O=C1NC(c2cccs2)Nc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Thiophen-2-yl-2,3-dihydro-1H-quinazolin-4-one page
Murcko scaffold O=C1NC(c2cccs2)Nc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1,2-Dihydro-2-(5-nitro-2-thienyl)quinazolin-4(3H)-one chemical structure, C12H9N3O3S, CAS 33389-33-2
1,2-Dihydro-2-(5-nitro-2-thienyl)quinazolin-4(3H)-one
CAS 33389-33-2C12H9N3O3S
2,3-Dihydro-1-methyl-2-(5-nitro-2-thienyl)-4(1H)-quinazolinone chemical structure, C13H11N3O3S, CAS 218144-80-0
2,3-Dihydro-1-methyl-2-(5-nitro-2-thienyl)-4(1H)-quinazolinone
CAS 218144-80-0C13H11N3O3S
1,3-Dimethyl-2-thiophen-2-yl-2,3-dihydro-1H-quinazolin-4-one chemical structure, C14H14N2OS, CAS 842955-69-5
1,3-Dimethyl-2-thiophen-2-yl-2,3-dihydro-1H-quinazolin-4-one
CAS 842955-69-5C14H14N2OS
2-Thiophen-2-yl-2,3-dihydro-1H-quinazolin-4-one chemical structure, C12H10N2OS, CAS 13324-83-9
2-Thiophen-2-yl-2,3-dihydro-1H-quinazolin-4-one
CAS 13324-83-9C12H10N2OS
2-(3-Methylthiophen-2-yl)-2,3-dihydro-1H-quinazolin-4-one chemical structure, C13H12N2OS, CAS 380190-54-5
2-(3-Methylthiophen-2-yl)-2,3-dihydro-1H-quinazolin-4-one
CAS 380190-54-5C13H12N2OS
3-Hydroxy-2-(5-nitrothiophen-2-yl)-2,3-dihydroquinazolin-4(1H)-one chemical structure, C12H9N3O4S, CAS 192513-24-9
3-Hydroxy-2-(5-nitrothiophen-2-yl)-2,3-dihydroquinazolin-4(1H)-one
CAS 192513-24-9C12H9N3O4S
2-(4-Bromothiophen-2-yl)-3-prop-2-enyl-1,2-dihydroquinazolin-4-one chemical structure, C15H13BrN2OS, CAS 875858-23-4
2-(4-Bromothiophen-2-yl)-3-prop-2-enyl-1,2-dihydroquinazolin-4-one
CAS 875858-23-4C15H13BrN2OS
3-Methyl-2-(3-methylthiophen-2-yl)-2,3-dihydroquinazolin-4(1H)-one chemical structure, C14H14N2OS, CAS 1354132-87-8
3-Methyl-2-(3-methylthiophen-2-yl)-2,3-dihydroquinazolin-4(1H)-one
CAS 1354132-87-8C14H14N2OS
BTYNB isomer chemical structure, C12H9BrN2OS, CAS 1262217-87-7
BTYNB isomer
CAS 1262217-87-7C12H9BrN2OS