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Murcko scaffold

Ring system with 2 rings and 12 atoms

9 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
9
With full pages
3
Scaffold SMILES

O=C1NN=CC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NN=CC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

3H-Pyrazol-3-one,2,4-dihydro-4-(4-methoxyphenyl)-5-methyl- chemical structure, C11H12N2O2, CAS 13051-07-5
3H-Pyrazol-3-one,2,4-dihydro-4-(4-methoxyphenyl)-5-methyl-
CAS 13051-07-5C11H12N2O2
4-Bromo-4-(4-methoxyphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C11H11BrN2O2, CAS 13051-08-6
4-Bromo-4-(4-methoxyphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one
CAS 13051-08-6C11H11BrN2O2
2,4-Dihydro-5-methyl-4-(3-methylphenyl)-3H-pyrazol-3-one chemical structure, C11H12N2O, CAS 885267-46-9
2,4-Dihydro-5-methyl-4-(3-methylphenyl)-3H-pyrazol-3-one
CAS 885267-46-9C11H12N2O
1,3-Dimethyl-4-phenyl-1,2-pyrazolin-5-one chemical structure, C11H12N2O, CAS 1706-41-8
1,3-Dimethyl-4-phenyl-1,2-pyrazolin-5-one
CAS 1706-41-8C11H12N2O
5-Oxo-4-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid chemical structure, C10H8N2O3, CAS 937650-39-0
5-Oxo-4-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid
CAS 937650-39-0C10H8N2O3
3-Amino-4-phenyl-4,5-dihydro-1H-pyrazol-5-one chemical structure, C9H9N3O, CAS 103755-48-2
3-Amino-4-phenyl-4,5-dihydro-1H-pyrazol-5-one
CAS 103755-48-2C9H9N3O
5-Amino-4-(3,4-difluorophenyl)-2,4-dihydro-3H-pyrazol-3-one chemical structure, C9H7F2N3O, CAS 1538670-21-1
5-Amino-4-(3,4-difluorophenyl)-2,4-dihydro-3H-pyrazol-3-one
CAS 1538670-21-1C9H7F2N3O
2-(3,4-Dimethyl-5-oxo-4-phenylpyrazol-1-yl)acetic acid chemical structure, C13H14N2O3, CAS 1383564-04-2
2-(3,4-Dimethyl-5-oxo-4-phenylpyrazol-1-yl)acetic acid
CAS 1383564-04-2C13H14N2O3
4-Ethyl-2,4-dihydro-5-methyl-4-phenyl-3H-pyrazol-3-one chemical structure, C12H14N2O, CAS 18182-53-1
4-Ethyl-2,4-dihydro-5-methyl-4-phenyl-3H-pyrazol-3-one
CAS 18182-53-1C12H14N2O