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Steroids and sterols

11alpha-Hydroxyprogesterone

Also known as 11alpha-hydroxypregn-4-ene-3,20-dione, 11-alpha-Hydroxypregn-4-ene-3,20-dione, 4-Pregnen-11alpha-ol-3,20-dione

CAS 80-75-1Formula C21H30O3Molar mass 330.47 g/molEC 201-306-9
GHS signal word: Warning. Pictograms: Harmful or irritant 4 suppliers listed
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11alpha-Hydroxyprogesterone chemical structure, C21H30O3, CAS 80-75-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
80-75-1
Formula
C21H30O3
Molar mass
330.47 g/mol
EC number
201-306-9
HS code
291440
Category
Steroids and sterols

What is 11alpha-Hydroxyprogesterone?

Plain description, key identifiers and synonyms

11alpha-hydroxyprogesterone is a 11alpha-hydroxy steroid that is pregn-4-ene-3,20-dione substituted by a hydroxy group at position 11. It is an 11alpha-hydroxy steroid, a 20-oxo steroid and a 3-oxo-Delta(4) steroid. It is functionally related to a progesterone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(8S,9S,10R,11R,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
CAS number
80-75-1 CAS number cross-checked
EC number
201-306-9
Molecular formula
C21H30O3
UNII
D8X4JXL4VM
MDL number
MFCD00003652
InChIKey
BFZHCUBIASXHPK-QJSKAATBSA-N
InChI
InChI=1S/C21H30O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17-,18+,19+,20-,21+/m0/s1
Canonical SMILES
CC(=O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3C(O)CC12C
Isomeric SMILES
CC(=O)[C@H]1CC[C@@H]2[C@@]1(C[C@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C

Synonyms

  • 11alpha-hydroxypregn-4-ene-3,20-dione
  • 11-alpha-Hydroxypregn-4-ene-3,20-dione
  • 4-Pregnen-11alpha-ol-3,20-dione
  • (11alpha)-11-hydroxypregn-4-ene-3,20-dione
  • Progesterone, 11alpha-hydroxy-
  • 11alpha-hydroxy progesterone
  • stetaderm
  • 11a-Hydroxy Progesterone
  • 11-alpha-HYDROXYPROGESTERONE
  • 11|A-Hydroxy Progesterone
  • (8S,9S,10R,11R,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  • 11?-Hydroxy Progesterone
  • 4-Pregnene-11a-ol-3,20-dione
  • (8S,9S,10R,11R,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
  • (11a)-11-Hydroxypregn-4-ene-3,20-dione
  • Pregn-4-ene-3,20-dione, 11-hydroxy-, (11alpha)-
  • 11alpha-Hydroxy-4-pregnene-3,20-dione
  • Pregn-4-ene-3,20-dione, 11alpha-hydroxy-
  • 11|_-Hydroxyprogesterone
  • 17-Acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
  • 11-Hydroxypregn-4-ene-3,20-dione #
  • (1S,3aS,3bS,9aR,9bS,10R,11aS)-1-acetyl-10-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
  • Pregn-4-ene-3,20-dione, 11alpha-hydroxy- (8CI)
  • Pregn-4-ene-3,20-dione,11-hydroxy-, (11alpha)-
  • C7FA0F45-BECD-4648-A1F3-7389ED9246EE
Show all 28 synonyms
  • Pregn-4-ene-3,20-dione, 11-hydroxy-, (11alpha)- (9CI)
  • (11alpha)-11-hydroxypregn-4-ene-3,20-dione, 11alpha-Hydroxyprogesterone, 4-pregnen-11alpha-ol-3,20-dione
  • (8S,10R,11R,13S,17S)-17-Acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
330.47 g/molcalc.
Exact mass
330.2195 Dacalc.
LogP (octanol/water)
3.69calc.
Topological polar surface area
54.37 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
1calc.
Heavy atoms
24calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.81calc.
Formal charge
0calc.
Stereocentres
7calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=C2CCC3C4CCCC4CCC3C2CC1

O=C1C=C2CCC3C4CCCC4CCC3C2CC1

4 rings, 18 atoms.

1,419 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

11alpha-Hydroxyprogesterone suppliers

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All 4 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

4 suppliers in 3 countries

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11alpha-Hydroxyprogesterone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: 11-alpha-Hydroxypregn-4-ene-3,20-dione and its esters, Ref no: 385, Annex ref: II/385

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 11alpha-Hydroxyprogesterone is traded under.

HS 2914.40Indicative HS code

Ketone-alcohols and ketone-aldehydes

World exports in 2024
$199M
+2.5% vs 2023, imports $247M
2019 to 2024
Top exporters
  1. China29.5%
  2. Germany14.4%
  3. Netherlands12.7%
Top importers
  1. United States37.2%
  2. Netherlands8.5%
  3. Germany6.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for 11alpha-Hydroxyprogesterone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 11alpha-Hydroxyprogesterone, based on the data on this page

What is 11alpha-Hydroxyprogesterone?

11alpha-hydroxyprogesterone is a 11alpha-hydroxy steroid that is pregn-4-ene-3,20-dione substituted by a hydroxy group at position 11. It is an 11alpha-hydroxy steroid, a 20-oxo steroid and a 3-oxo-Delta(4) steroid. It is functionally related to a progesterone.

What is the CAS number of 11alpha-Hydroxyprogesterone?

The CAS registry number of 11alpha-Hydroxyprogesterone is 80-75-1.

What is the molecular formula and weight of 11alpha-Hydroxyprogesterone?

The molecular formula of 11alpha-Hydroxyprogesterone is C21H30O3 and its molar mass is 330.47 g/mol.

Is 11alpha-Hydroxyprogesterone hazardous?

11alpha-Hydroxyprogesterone carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 11alpha-Hydroxyprogesterone?

11alpha-Hydroxyprogesterone is usually classified under HS code 291440 (Ketone-alcohols and ketone-aldehydes). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 11alpha-Hydroxyprogesterone?

CompoundList lists 4 suppliers of 11alpha-Hydroxyprogesterone in Czech Republic, Hong Kong and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of 11alpha-Hydroxyprogesterone?

Suppliers quote 11alpha-Hydroxyprogesterone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 11alpha-Hydroxyprogesterone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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