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Screening compounds

4Sc-203

Also known as 4sc 203, Urea, N-(2-methoxy-5-methylphenyl)-N'-(6-((6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-4-quinazolinyl)amino)-2-benzothiazolyl)-, 1-(2-methoxy-5-methylphenyl)-3-[6-[[6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-yl]amino]-1,3-benzothiazol-2-yl]urea

CAS 895533-09-2Formula C33H38N8O4SMolar mass 642.79 g/mol
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4Sc-203 chemical structure, C33H38N8O4S, CAS 895533-09-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
895533-09-2
Formula
C33H38N8O4S
Molar mass
642.79 g/mol
HS code
293420
Category
Screening compounds

What is 4Sc-203?

Plain description, key identifiers and synonyms

Multikinase Inhibitor 4SC-203 is a multikinase inhibitor with potential antineoplastic activity. Multikinase inhibitor 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEGFRs). This may result in the inhibition of angiogenesis and cell proliferation in tumor cells in which these kinases are upregulated. FLT3 (FLK2), a class III tyrosine kinase receptor, is overexpressed or mutated in most B lineage and acute myeloid leukemias (AML). VEGFRs, tyrosine kinase receptors, are overexpressed in a variety of tumor cell types and play key roles in angiogenesis.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-(2-methoxy-5-methylphenyl)-3-[6-[[6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-yl]amino]-1,3-benzothiazol-2-yl]urea
CAS number
895533-09-2
Molecular formula
C33H38N8O4S
UNII
RFG3GJ6251
InChIKey
MAFACRSJGNJHCF-UHFFFAOYSA-N
InChI
InChI=1S/C33H38N8O4S/c1-21-6-9-27(43-3)26(16-21)37-32(42)39-33-38-24-8-7-22(17-30(24)46-33)36-31-23-18-28(44-4)29(19-25(23)34-20-35-31)45-15-5-10-41-13-11-40(2)12-14-41/h6-9,16-20H,5,10-15H2,1-4H3,(H,34,35,36)(H2,37,38,39,42)
SMILES (canonical and isomeric)
CC1=CC(=C(C=C1)OC)NC(=O)NC2=NC3=C(S2)C=C(C=C3)NC4=NC=NC5=CC(=C(C=C54)OC)OCCCN6CCN(CC6)C

Synonyms

  • 4sc 203
  • Urea, N-(2-methoxy-5-methylphenyl)-N'-(6-((6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-4-quinazolinyl)amino)-2-benzothiazolyl)-
  • 1-(2-methoxy-5-methylphenyl)-3-[6-[[6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-yl]amino]-1,3-benzothiazol-2-yl]urea
  • 1-(2-methoxy-5-methylphenyl)-3-(6-((6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinazolin-4-yl)amino)-1,3-benzothiazol-2-yl)urea
  • 1-(2-methoxy-5-methylphenyl)-3-[6-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-yl}amino)-1,3-benzothiazol-2-yl]urea
  • Multikinase Inhibitor 4SC-203
  • SC 71710
  • 4SC203, 4SC-203, 4SC 203, SC71710, SC-71710, SC 71710
  • 1-(2-methoxy-5-methylphenyl)-3-(6-((6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinazolin-4-yl)amino)benzo[d]thiazol-2-yl)urea

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
642.79 g/molcalc.
Exact mass
642.2737 Dacalc.
LogP (octanol/water)
5.97calc.
Topological polar surface area
126 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
11calc.
Rotatable bonds
11calc.
Heavy atoms
46calc.
Rings
6calc.
Aromatic rings
5calc.
Fraction sp3 carbons
0.33calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Nc1ccccc1)Nc1nc2ccc(Nc3ncnc4cc(OCCCN5CCNCC5)ccc34)cc2s1

O=C(Nc1ccccc1)Nc1nc2ccc(Nc3ncnc4cc(OCCCN5CCNCC5)ccc34)cc2s1

6 rings, 40 atoms.

No other chemical in our database has this scaffold.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

4Sc-203 suppliers

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4Sc-203 price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antineoplastic agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 4Sc-203 is traded under.

HS 2934.20Indicative HS code

Compounds containing in the structure a benzothiazole ring-system (whether or not…

World exports in 2024
$662M
+4.3% vs 2023, imports $630M
2019 to 2024
Top exporters
  1. China62.9%
  2. Belgium14.6%
  3. United States5.4%
Top importers
  1. India * partner reported18.5%
  2. United States18.1%
  3. Brazil6.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 4Sc-203 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 4Sc-203, based on the data on this page

What is 4Sc-203?

Multikinase Inhibitor 4SC-203 is a multikinase inhibitor with potential antineoplastic activity. Multikinase inhibitor 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEGFRs).

What is the CAS number of 4Sc-203?

The CAS registry number of 4Sc-203 is 895533-09-2.

What is the molecular formula and weight of 4Sc-203?

The molecular formula of 4Sc-203 is C33H38N8O4S and its molar mass is 642.79 g/mol.

What is 4Sc-203 used for?

Known uses and roles of 4Sc-203 include building blocks in research and laboratory, screening compounds in research and laboratory, antineoplastic agent and pharmaceutical.

Is 4Sc-203 hazardous?

No GHS hazard classification for 4Sc-203 is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of 4Sc-203?

4Sc-203 is usually classified under HS code 293420 (Compounds containing in the structure a benzothiazole ring-system (whether or not…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 4Sc-203?

Post a free request on CompoundList and suppliers of 4Sc-203 will send you quotes. Your contact details stay private until you accept a quote.

What is the price of 4Sc-203?

Suppliers quote 4Sc-203 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 4Sc-203

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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