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Aromatic building blocks

5-Hydroxythalidomide

Also known as 2-(2,6-dioxopiperidin-3-yl)-5-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione, 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-hydroxy-, Thalidomide-5-OH

CAS 64567-60-8Formula C13H10N2O5Molar mass 274.23 g/molEC 965-879-3
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant 7 suppliers listed
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5-Hydroxythalidomide chemical structure, C13H10N2O5, CAS 64567-60-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
64567-60-8
Formula
C13H10N2O5
Molar mass
274.23 g/mol
EC number
965-879-3
HS code
292519
Category
Aromatic building blocks

What is 5-Hydroxythalidomide?

Plain description, key identifiers and synonyms

5-Hydroxythalidomide is a member of phthalimides.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindole-1,3-dione
CAS number
64567-60-8 CAS number cross-checkedOther or deprecated CAS: 172333-29-8, 250384-12-4
EC number
965-879-3
Molecular formula
C13H10N2O5
UNII
29V976C3CJ
MDL number
MFCD24386541
InChIKey
LJBQRRQTZUJWRC-UHFFFAOYSA-N
InChI
InChI=1S/C13H10N2O5/c16-6-1-2-7-8(5-6)13(20)15(12(7)19)9-3-4-10(17)14-11(9)18/h1-2,5,9,16H,3-4H2,(H,14,17,18)
SMILES (canonical and isomeric)
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)O

Synonyms

  • 2-(2,6-dioxopiperidin-3-yl)-5-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione
  • 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-hydroxy-
  • Thalidomide-5-OH
  • 2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione
  • 2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindole-1,3-dione
  • alpha-N-(4-Hydroxyphthalimido)-glutarimide
  • 2-(2,6-Dioxo-3-piperidyl)-5-hydroxy-isoindoline-1,3-dione
  • (+/-)-Hydroxythalidomide
  • 2-(2,6-Dioxo-3-piperidinyl)-5-hydroxy-1H-isoindole-1,3(2H)-dione
  • Thalidomide-5'-OH
  • Thalidomide-5-OH?
  • 5-HYDR
  • 5-Hydroxy thalidomide
  • 5-Hydroxy thalidomide, (+/-)-
  • Phthalimide, N-(2,6-dioxo-3-piperidyl)-4-hydroxy-
  • 2-(2,6-Dioxo-3-piperidinyl)-5-hydroxy-1,3-isoindolinedione
  • 5-Hydroxy-2-(6-hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-3-yl)-1H-isoindole-1,3(2H)-dione

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
274.23 g/molcalc.
Exact mass
274.059 Dacalc.
LogP (octanol/water)
-0.21calc.
Topological polar surface area
103.8 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
1calc.
Heavy atoms
20calc.
Rings
3calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.23calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1

O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1

3 rings, 19 atoms, the Thalidomide ring system.

1,721 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H301Toxic if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
Precautionary statements (14)
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

5-Hydroxythalidomide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 7 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

7 suppliers in 3 countries

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5-Hydroxythalidomide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 5-Hydroxythalidomide is traded under.

HS 2925.19Indicative HS code

Imides and their derivatives, salts thereof, other

World exports in 2024
$295M
+11.7% vs 2023, imports $348M
2019 to 2024
Top exporters
  1. China29.7%
  2. Japan22.7%
  3. United Kingdom10.0%
Top importers
  1. United States12.7%
  2. Brazil12.6%
  3. China10.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for 5-Hydroxythalidomide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 5-Hydroxythalidomide, based on the data on this page

What is 5-Hydroxythalidomide?

5-Hydroxythalidomide is a member of phthalimides.

What is the CAS number of 5-Hydroxythalidomide?

The CAS registry number of 5-Hydroxythalidomide is 64567-60-8. Other or deprecated CAS numbers: 172333-29-8, 250384-12-4.

What is the molecular formula and weight of 5-Hydroxythalidomide?

The molecular formula of 5-Hydroxythalidomide is C13H10N2O5 and its molar mass is 274.23 g/mol.

What is 5-Hydroxythalidomide used for?

Known uses and roles of 5-Hydroxythalidomide include building blocks in research and laboratory and screening compounds in research and laboratory.

Is 5-Hydroxythalidomide hazardous?

5-Hydroxythalidomide carries the GHS signal word "Danger". Main hazards: toxic if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 5-Hydroxythalidomide?

5-Hydroxythalidomide is usually classified under HS code 292519 (Imides and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 5-Hydroxythalidomide?

CompoundList lists 7 suppliers of 5-Hydroxythalidomide in United States, China and Czech Republic. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of 5-Hydroxythalidomide?

Suppliers quote 5-Hydroxythalidomide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 5-Hydroxythalidomide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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