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alpha-Ketoglutarate

Also known as 2-oxopentanedioate, 2 Ketoglutarate, 2 Oxoglutarate

CAS 64-15-3Formula C5H4O5-2Molar mass 144.08 g/mol
alpha-Ketoglutarate chemical structure, C5H4O5-2, CAS 64-15-3
2D chemical structure

Key facts

What buyers check first

CAS number
64-15-3
Formula
C5H4O5-2
Molar mass
144.08 g/mol
HS code
291830
Category
Carboxylic acids and anhydrides

What is alpha-Ketoglutarate?

Plain description, key identifiers and synonyms

2-oxoglutarate(2-) is an oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid. It has a role as a geroprotector, a Saccharomyces cerevisiae metabolite, a human metabolite and an algal metabolite. It is functionally related to a glutarate(2-). It is a conjugate base of a 2-oxoglutarate(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-oxopentanedioate
CAS number
64-15-3 CAS number cross-checked
Molecular formula
C5H4O5-2
InChIKey
KPGXRSRHYNQIFN-UHFFFAOYSA-L
InChI
InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)/p-2
SMILES (canonical and isomeric)
C(CC(=O)[O-])C(=O)C(=O)[O-]

Synonyms

  • 2-oxopentanedioate
  • 2 Ketoglutarate
  • 2 Oxoglutarate
  • alpha oxoglutarate
  • ketoglutarate
  • 2-oxoglutarate(2-)
  • 2-ketoglutarate
  • Pentanedioic acid, 2-oxo-, ion(2-)
  • 2-oxopentanedionate
  • 2-Oxoglutamate
  • Pentanedioic acid,2-oxo-, ion(2-)
  • alphaketoglutarate
  • alpha-oxoglutarate
  • 2xzw
  • 3hww
  • 2-oxopentanedionic acid
  • 4-Carboxy-2-oxo-butyrate
  • 2-oxopentanedioic acid, ion(2-)
  • 4-Carboxy-2-oxo-butyric acid anion

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
144.08 g/molcalc.
Exact mass
144.007 Dacalc.
LogP (octanol/water)
-3.16calc.
Topological polar surface area
97.33 ร…ยฒcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
4calc.
Heavy atoms
10calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.4calc.
Formal charge
-2calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

alpha-Ketoglutarate suppliers

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alpha-Ketoglutarate price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • Saccharomyces cerevisiae metabolite
  • algal metabolite
  • animal metabolite
  • eukaryotic metabolite
  • fungal metabolite
  • geroprotector
  • human metabolite
  • mammalian metabolite
  • metabolite
  • pharmaceutical
  • protective agent

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code alpha-Ketoglutarate is traded under.

HS 2918.30Indicative HS code

Carboxylic acids with aldehyde or ketone function but without other oxygen functionโ€ฆ

World exports in 2024
$813M
โˆ’39.8% vs 2023, imports $1.23B
2019 to 2024
Top exporters
  1. China43.3%
  2. India * partner reported10.4%
  3. United States6.8%
Top importers
  1. Singapore33.1%
  2. Germany7.2%
  3. Japan6.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for alpha-Ketoglutarate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about alpha-Ketoglutarate, based on the data on this page

What is alpha-Ketoglutarate?

2-oxoglutarate(2-) is an oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid. It has a role as a geroprotector, a Saccharomyces cerevisiae metabolite, a human metabolite and an algal metabolite. It is functionally related to a glutarate(2-).

What is the CAS number of alpha-Ketoglutarate?

The CAS registry number of alpha-Ketoglutarate is 64-15-3.

What is the molecular formula and weight of alpha-Ketoglutarate?

The molecular formula of alpha-Ketoglutarate is C5H4O5-2 and its molar mass is 144.08 g/mol.

What is alpha-Ketoglutarate used for?

Known uses and roles of alpha-Ketoglutarate include building blocks in research and laboratory, saccharomyces cerevisiae metabolite, algal metabolite, animal metabolite, eukaryotic metabolite and 7 more.

Is alpha-Ketoglutarate hazardous?

No GHS hazard classification for alpha-Ketoglutarate is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of alpha-Ketoglutarate?

alpha-Ketoglutarate is usually classified under HS code 291830 (Carboxylic acids with aldehyde or ketone function but without other oxygen functionโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy alpha-Ketoglutarate?

CompoundList lists 7 suppliers of alpha-Ketoglutarate in China, Spain and United Kingdom. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of alpha-Ketoglutarate?

Suppliers quote alpha-Ketoglutarate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle alpha-Ketoglutarate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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