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Screening compounds

Cep-9722

Also known as 1H-Cyclopenta(a)pyrrolo(3,4-C)carbazole-1,3(2H)-dione, 4,5,6,7-tetrahydro-11-methoxy-2-((4-methyl-1-piperazinyl)methyl)-, 4,5,6,7-Tetrahydro-11-methoxy-2-((4-methyl-1-piperazinyl)methyl)-1H-cyclopenta(a)pyrrolo(3,4-C)carbazole-1,3(2H)-dione, PARP Inhibitor CEP-9722

CAS 916574-83-9Formula C24H26N4O3Molar mass 418.50 g/mol
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Cep-9722 chemical structure, C24H26N4O3, CAS 916574-83-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
916574-83-9
Formula
C24H26N4O3
Molar mass
418.50 g/mol
HS code
293359
Category
Screening compounds

What is Cep-9722?

Plain description, key identifiers and synonyms

PARP Inhibitor CEP-9722 is a small-molecule prodrug of CEP-8983, a novel 4-methoxy-carbazole inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration and conversion from CEP-9722, CEP-8983 selectively binds to PARP 1 and 2, preventing repair of damaged DNA via base excision repair (BER). This agent enhances the accumulation of DNA strand breaks and promotes genomic instability and apoptosis. CEP-8983 may potentiate the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins that signal and recruit other proteins to repair damaged DNA and can be activated by single strand breaks in DNA.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
14-methoxy-9-[(4-methylpiperazin-1-yl)methyl]-9,19-diazapentacyclo[10.7.0.02,6.07,11.013,18]nonadeca-1(12),2(6),7(11),13(18),14,16-hexaene-8,10-dione
CAS number
916574-83-9
Molecular formula
C24H26N4O3
UNII
B68083E4YG
InChIKey
CTLOSZHDGZLOQE-UHFFFAOYSA-N
InChI
InChI=1S/C24H26N4O3/c1-26-9-11-27(12-10-26)13-28-23(29)18-14-5-3-6-15(14)22-20(21(18)24(28)30)19-16(25-22)7-4-8-17(19)31-2/h4,7-8,25H,3,5-6,9-13H2,1-2H3
SMILES (canonical and isomeric)
CN1CCN(CC1)CN2C(=O)C3=C(C2=O)C4=C(C5=C3CCC5)NC6=C4C(=CC=C6)OC

Synonyms

  • 1H-Cyclopenta(a)pyrrolo(3,4-C)carbazole-1,3(2H)-dione, 4,5,6,7-tetrahydro-11-methoxy-2-((4-methyl-1-piperazinyl)methyl)-
  • 4,5,6,7-Tetrahydro-11-methoxy-2-((4-methyl-1-piperazinyl)methyl)-1H-cyclopenta(a)pyrrolo(3,4-C)carbazole-1,3(2H)-dione
  • PARP Inhibitor CEP-9722
  • 14-methoxy-9-((4-methylpiperazin-1-yl)methyl)-9,19-diazapentacyclo(10.7.0.0^(2,6).0^(7,11).0^(13,18))nonadeca-1(12),2(6),7(11),13(18),14,16-hexaene-8,10-dione
  • CEP 9722
  • 11-methoxy-2-((4-methylpiperazin-1-yl)methyl)-4,5,6,7-tetrahydro-1H-cyclopenta[a]pyrrolo[3,4-c]carbazole-1,3(2H)-dione
  • 14-methoxy-9-[(4-methylpiperazin-1-yl)methyl]-9,19-diazapentacyclo[10.7.0.02,6.07,11.013,18]nonadeca-1(12),2(6),7(11),13(18),14,16-hexaene-8,10-dione

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
418.50 g/molcalc.
Exact mass
418.2005 Dacalc.
LogP (octanol/water)
2.62calc.
Topological polar surface area
68.88 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
3calc.
Heavy atoms
31calc.
Rings
6calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.42calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1c2c3c(c4[nH]c5ccccc5c4c2C(=O)N1CN1CCNCC1)CCC3

O=C1c2c3c(c4[nH]c5ccccc5c4c2C(=O)N1CN1CCNCC1)CCC3

6 rings, 28 atoms.

No other chemical in our database has this scaffold.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Cep-9722 suppliers

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Cep-9722 price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antineoplastic agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cep-9722 is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Cep-9722 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cep-9722, based on the data on this page

What is Cep-9722?

PARP Inhibitor CEP-9722 is a small-molecule prodrug of CEP-8983, a novel 4-methoxy-carbazole inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity.

What is the CAS number of Cep-9722?

The CAS registry number of Cep-9722 is 916574-83-9.

What is the molecular formula and weight of Cep-9722?

The molecular formula of Cep-9722 is C24H26N4O3 and its molar mass is 418.50 g/mol.

What is Cep-9722 used for?

Known uses and roles of Cep-9722 include building blocks in research and laboratory, screening compounds in research and laboratory, antineoplastic agent and pharmaceutical.

Is Cep-9722 hazardous?

No GHS hazard classification for Cep-9722 is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Cep-9722?

Cep-9722 is usually classified under HS code 293359 (Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Cep-9722?

Post a free request on CompoundList and suppliers of Cep-9722 will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Cep-9722?

Suppliers quote Cep-9722 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Cep-9722

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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