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Aromatic building blocks

Chlorpropamide

Also known as Diabinese, Glucamide, Diabenese

CAS 94-20-2Formula C10H13ClN2O3SMolar mass 276.75 g/molEC 202-314-5
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard 90 suppliers listed
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Chlorpropamide chemical structure, C10H13ClN2O3S, CAS 94-20-2
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from dil ethanol
Melting point
127 to 129
Solubility
2.2 mg/ml in water @ pH 6, practically insol in water @ pH 7.3, sol in alcohol, moderate…
HS code
293590
Category
Aromatic building blocks
Illustrative photo, a shrink wrapped pallet of kraft paper sacks in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Chlorpropamide?

Plain description, key identifiers and synonyms

Chlorpropamide is an N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification. It has a role as a hypoglycemic agent and an insulin secretagogue. It is a N-sulfonylurea and a member of monochlorobenzenes.

Chlorpropamide is a kiwanja cha kemikali.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-(4-chlorophenyl)sulfonyl-3-propylurea
CAS number
94-20-2 CAS number cross-checked
EC number
202-314-5
Molecular formula
C10H13ClN2O3S
UNII
WTM2C3IL2X
MDL number
MFCD00079004
InChIKey
RKWGIWYCVPQPMF-UHFFFAOYSA-N
InChI
InChI=1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)
SMILES (canonical and isomeric)
CCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)Cl

Synonyms

  • Diabinese
  • Glucamide
  • Diabenese
  • Melitase
  • 4-chloro-N-(propylcarbamoyl)benzenesulfonamide
  • Clorpropamida
  • Clorpropamide
  • Clorpropamid
  • Prodiaben
  • Chlorpropamidum
  • 1-(p-Chlorobenzenesulfonyl)-3-propylurea
  • 1-Propyl-3-(p-chlorobenzenesulfonyl)urea
  • N-(4-Chlorophenylsulfonyl)-N'-propylurea
  • N-(p-Chlorobenzenesulfonyl)-N'-propylurea
  • N-Propyl-N'-(p-chlorobenzenesulfonyl)urea
  • 1-(p-Chlorophenylsulfonyl)-3-propylurea
  • 4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide
  • 4-Chloro-N-((propylamino)carbonyl)benzenesulfonamide
  • 1-(4-chlorobenzenesulfonyl)-3-propylurea
  • n-Propyl-N'-p-chlorophenylsulfonylcarbamide
  • Benzenesulfonamide, 4-chloro-N-((propylamino)carbonyl)-
  • 1-[(4-chlorobenzene)sulfonyl]-3-propylurea
  • Benzenesulfonamide, 4-chloro-N-[(propylamino)carbonyl]-
  • Urea, 1-((p-chloropenyl)sulfonyl)-3-propyl-
  • Urea, 1-((p-chlorophenyl)sulfonyl)-3-propyl-
Show all 38 synonyms
  • 1-[p-Chlorobenzenesulfonyl]-3-propylurea
  • Urea, 1-[(p-chlorophenyl)sulfonyl]-3-propyl-
  • 1-((4-chlorobenzene)sulfonyl)-3-propylurea
  • Diabemide
  • Glymese
  • Chloropropamide
  • Meldian
  • Chlorpropamid
  • Chloronase
  • Diabetoral
  • Adiaben
  • Catanil
  • Chlorodiabina

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from dil ethanolexp.
Odour
SLIGHT ODORexp.
Melting point
127 to 129exp.
Solubility
2.2 mg/ml in water @ pH 6, practically insol in water @ pH 7.3, sol in alcohol, moderately sol in chloroform, sparingly sol in ether, benzeneexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
276.75 g/molcalc.
Exact mass
276.0335 Dacalc.
LogP (octanol/water)
1.74calc.
Topological polar surface area
75.27 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
17calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.3calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H312 + H332Harmful in contact with skin. Harmful if inhaled.
  • H312Harmful in contact with skin.
  • H332Harmful if inhaled.
  • H351Suspected of causing cancer.
Precautionary statements (12)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Chlorpropamide suppliers

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All 90 suppliers
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Where suppliers are based

90 suppliers in 14 countries

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Chlorpropamide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Antidiabetic.

Veterinary medication:.

Use classes: Pharmaceuticals.

Pharmacological actions

  • Hypoglycemic Agents

Roles

  • hypoglycemic agent
  • insulin secretagogue
  • pharmaceutical
  • secretagogue

Pharmacology

Chlorpropamide is a Sulfonylurea.

How it is made

Marshall, Sigal, J Org Chem 23, 927 (1958), Brit Pat 853,555 (1960 to Pfizer)...

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Chlorpropamide (INN), Ref no: 79, Annex ref: II/79

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Chlorpropamide is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Chlorpropamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Chlorpropamide, based on the data on this page

What is Chlorpropamide?

Chlorpropamide is an N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group.

What is the CAS number of Chlorpropamide?

The CAS registry number of Chlorpropamide is 94-20-2.

What is the molecular formula and weight of Chlorpropamide?

The molecular formula of Chlorpropamide is C10H13ClN2O3S and its molar mass is 276.75 g/mol.

What is Chlorpropamide used for?

Antidiabetic. Veterinary medication:. Use classes: Pharmaceuticals.

Is Chlorpropamide hazardous?

Chlorpropamide carries the GHS signal word "Warning". Main hazards: harmful in contact with skin. harmful if inhaled, harmful in contact with skin, harmful if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Chlorpropamide?

Chlorpropamide is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Chlorpropamide?

CompoundList lists 90 suppliers of Chlorpropamide in United States, China, India, Germany and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Chlorpropamide in India?

6 suppliers in India list Chlorpropamide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Chlorpropamide?

Suppliers quote Chlorpropamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Chlorpropamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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