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Aromatic building blocks

Dexfenfluramine

Also known as d-Fenfluramine, (+)-Fenfluramine, Dextrofenfluramine

CAS 3239-44-9Formula C12H16F3NMolar mass 231.26 g/mol
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Dexfenfluramine chemical structure, C12H16F3N, CAS 3239-44-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
3239-44-9
Formula
C12H16F3N
Molar mass
231.26 g/mol
HS code
292149
Category
Aromatic building blocks

What is Dexfenfluramine?

Plain description, key identifiers and synonyms

(S)-fenfluramine is the S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects. It has a role as a serotonergic agonist, an appetite depressant and a serotonin uptake inhibitor. It is an enantiomer of a (R)-fenfluramine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
CAS number
3239-44-9 CAS number cross-checked
Molecular formula
C12H16F3N
UNII
E35R3G56OV
InChIKey
DBGIVFWFUFKIQN-VIFPVBQESA-N
InChI
InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1
Canonical SMILES
CCNC(C)Cc1cccc(C(F)(F)F)c1
Isomeric SMILES
CCN[C@@H](C)CC1=CC(=CC=C1)C(F)(F)F

Synonyms

  • d-Fenfluramine
  • (+)-Fenfluramine
  • Dextrofenfluramine
  • (S)-Fenfluramine
  • Dexfenfluramina
  • Dexfenfluraminum
  • Isolipan
  • Redux
  • d-N-Ethyl-alpha-methyl-m-trifluoromethylphenethylamine
  • (S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
  • ethyl[(2S)-1-[3-(trifluoromethyl)phenyl]propan-2-yl]amine
  • Phenethylamine, N-ethyl-alpha-methyl-m-(trifluoromethyl)-, (S)-
  • Benzeneethanamine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-, (S)-
  • (S)-N-ethyl-1-(3-(trifluoromethyl)phenyl)propan-2-amine
  • ethyl((2S)-1-(3-(trifluoromethyl)phenyl)propan-2-yl)amine
  • Fenfluramine d-
  • (2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
  • Fenfluramine d-form
  • Dexfenfluramine (INN)
  • DEA No. 1670
  • ip001
  • D-(+)-Fenfluramine
  • (S)-(+)-Fenfluramine
  • PDSP1_000695
  • PDSP1_001419
Show all 28 synonyms
  • PDSP2_000685
  • PDSP2_001403
  • (+)-(S)-N-Ethyl-a-methyl-m-(trifluoromethyl)phenethylamine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
231.26 g/molcalc.
Exact mass
231.1235 Dacalc.
LogP (octanol/water)
3.25calc.
Topological polar surface area
12.03 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
4calc.
Heavy atoms
16calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Dexfenfluramine suppliers

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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

1 supplier in 1 country

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Dexfenfluramine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

In the treatment of severe obesity. (Former use).

Appetite suppressant for the short-term (a few weeks) management of obesity. (Former use).

Pharmacological actions

  • Serotonin Receptor Agonists

Roles

  • anti-obesity agent
  • appetite depressant
  • appetite regulator
  • neurotransmitter agent
  • pharmaceutical
  • serotonergic agonist
  • serotonergic drug
  • serotonin uptake inhibitor

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dexfenfluramine is traded under.

HS 2921.49Indicative HS code

Aromatic monoamines and their derivatives, salts thereof, other

World exports in 2024
$1.14B
+5.6% vs 2023, imports $1.06B
2019 to 2024
Top exporters
  1. Germany23.3%
  2. China19.4%
  3. Singapore14.6%
Top importers
  1. Belgium15.9%
  2. South Korea15.0%
  3. Germany12.8%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Dexfenfluramine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dexfenfluramine, based on the data on this page

What is Dexfenfluramine?

(S)-fenfluramine is the S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity.

What is the CAS number of Dexfenfluramine?

The CAS registry number of Dexfenfluramine is 3239-44-9.

What is the molecular formula and weight of Dexfenfluramine?

The molecular formula of Dexfenfluramine is C12H16F3N and its molar mass is 231.26 g/mol.

What is Dexfenfluramine used for?

In the treatment of severe obesity. (Former use). Appetite suppressant for the short-term (a few weeks) management of obesity. (Former use).

Is Dexfenfluramine hazardous?

No GHS hazard classification for Dexfenfluramine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Dexfenfluramine?

Dexfenfluramine is usually classified under HS code 292149 (Aromatic monoamines and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Dexfenfluramine?

CompoundList lists 1 supplier of Dexfenfluramine in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Dexfenfluramine?

Suppliers quote Dexfenfluramine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Dexfenfluramine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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