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Central nervous system drugs

Dyclonine

Also known as Dyclocaine, Diclonina, Dycloninum

CAS 586-60-7Formula C18H27NO2Molar mass 289.42 g/mol
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Dyclonine chemical structure, C18H27NO2, CAS 586-60-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
586-60-7
Formula
C18H27NO2
Molar mass
289.42 g/mol
HS code
293339
Category
Central nervous system drugs

What is Dyclonine?

Plain description, key identifiers and synonyms

Dyclonine is N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group. It has a role as a topical anaesthetic. It is a member of piperidines and an aromatic ketone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one
CAS number
586-60-7 CAS number cross-checked
Molecular formula
C18H27NO2
UNII
078A24Q30O
InChIKey
BZEWSEKUUPWQDQ-UHFFFAOYSA-N
InChI
InChI=1S/C18H27NO2/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19/h7-10H,2-6,11-15H2,1H3
SMILES (canonical and isomeric)
CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2

Synonyms

  • Dyclocaine
  • Diclonina
  • Dycloninum
  • 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one
  • 4'-Butoxy-3-piperidinopropiophenone
  • 3-Piperidino-4'-butoxypropiophenone
  • 2-(1-piperidyl)ethyl p-butoxyphenyl ketone
  • 4-butoxy-beta-piperidinopropiophenone
  • 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone
  • 4-n-butoxy-beta-(1-piperidyl)propiophenone
  • 1-propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)
  • 1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-
  • Dyclonin
  • Dyclocainum
  • 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one
  • 1-Propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)-
  • Dyclonine (INN)
  • Propiophenone, 4'-butoxy-3-piperidino-
  • Dyclone (Salt/Mix)
  • Tanaclone (Salt/Mix)
  • DivK1c_000632
  • 1-(4-butoxyphenyl)-3-piperidylpropan-1-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
289.42 g/molcalc.
Exact mass
289.2042 Dacalc.
LogP (octanol/water)
3.92calc.
Topological polar surface area
29.54 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
8calc.
Heavy atoms
21calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.61calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CCN1CCCCC1)c1ccccc1

O=C(CCN1CCCCC1)c1ccccc1

2 rings, 16 atoms, the 3-Piperidinopropiophenone ring system.

187 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Dyclonine suppliers

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All 5 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

5 suppliers in 3 countries

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Dyclonine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Anesthetics, Local

Roles

  • anaesthetic
  • local anaesthetic
  • pharmaceutical
  • topical anaesthetic

Pharmacology

Dyclonine is an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dyclonine is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Dyclonine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dyclonine, based on the data on this page

What is Dyclonine?

Dyclonine is N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group. It has a role as a topical anaesthetic. It is a member of piperidines and an aromatic ketone.

What is the CAS number of Dyclonine?

The CAS registry number of Dyclonine is 586-60-7.

What is the molecular formula and weight of Dyclonine?

The molecular formula of Dyclonine is C18H27NO2 and its molar mass is 289.42 g/mol.

What is Dyclonine used for?

Use classes: Pharmaceuticals.

Is Dyclonine hazardous?

No GHS hazard classification for Dyclonine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Dyclonine?

Dyclonine is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Dyclonine?

CompoundList lists 5 suppliers of Dyclonine in China, Hong Kong and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Dyclonine?

Suppliers quote Dyclonine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Dyclonine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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