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Aromatic building blocks

Physcion

Also known as Physcione, Rheochrysidin, Emodin 3-methyl ether

CAS 521-61-9Formula C16H12O5Molar mass 284.27 g/molEC 208-315-7
GHS signal word: Warning. Pictograms: Harmful or irritant 33 suppliers listed
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Physcion chemical structure, C16H12O5, CAS 521-61-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
521-61-9
Formula
C16H12O5
Molar mass
284.27 g/mol
EC number
208-315-7
HS code
291469
Category
Aromatic building blocks

What is Physcion?

Plain description, key identifiers and synonyms

Physcion is a dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6. It has been widely isolated and characterised from both terrestrial and marine sources. It has a role as a metabolite, an antibacterial agent, an antineoplastic agent, an antifungal agent, a hepatoprotective agent, an anti-inflammatory agent and an apoptosis inducer. It is functionally related to a 2-methylanthraquinone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,8-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione
CAS number
521-61-9 CAS number cross-checked
EC number
208-315-7
Molecular formula
C16H12O5
UNII
H6PT94IV61
MDL number
MFCD00017374
InChIKey
FFWOKTFYGVYKIR-UHFFFAOYSA-N
InChI
InChI=1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3
SMILES (canonical and isomeric)
CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)OC

Synonyms

  • Physcione
  • Rheochrysidin
  • Emodin 3-methyl ether
  • 1,8-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione
  • 1,8-Dihydroxy-3-methoxy-6-methyl-9,10-anthracenedione
  • Parienin
  • Emodin monomethyl ether
  • Anthraquinone, 1,8-dihydroxy-3-methoxy-6-methyl-
  • Emodin-3-methyl ether
  • 1,8-Dihydroxy-3-methoxy-6-methylanthraquinone
  • 1,8-Dihydroxy-3-methyl-6-methoxyanthraquinone
  • Parietin, Rheochrysidin
  • 1,8-Dihydroxy-3-methyl-6-methoxy-9,10-anthraquinone
  • Rheochrysidin (Physcione)
  • 1,8-Dihydroxy-3-methoxy-6-methyl-anthraquinone
  • 1,8-dihydroxy-3-methoxy-6-methyl-anthracene-9,10-dione
  • 9,10-Anthracenedione, 1,8-dihydroxy-3-methoxy-6-methyl-
  • Methoxyemodin
  • 6-o-Methylemodin
  • fischione
  • physicion
  • Physcion (Standard)
  • emodin monomethylether
  • Physcione-
  • 1,8-dihydroxy-6-methoxy-3-methylanthraquinone
Show all 29 synonyms
  • Physcion, analytical standard
  • DivK1c_006567
  • MEGxm0_000018
  • Physcion, >=98.0% (TLC)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
284.27 g/molcalc.
Exact mass
284.0685 Dacalc.
LogP (octanol/water)
2.19calc.
Topological polar surface area
83.83 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
1calc.
Heavy atoms
21calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.13calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1c2ccccc2C(=O)c2ccccc21

O=C1c2ccccc2C(=O)c2ccccc21

3 rings, 16 atoms, the Anthraquinone ring system.

2,059 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Physcion suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 33 suppliers
30 of 30 offers

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Where suppliers are based

33 suppliers in 7 countries

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Physcion price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Roles

  • anti-inflammatory agent
  • antibacterial agent
  • antifungal agent
  • antimicrobial agent
  • antineoplastic agent
  • apoptosis inducer
  • hepatoprotective agent
  • metabolite
  • pharmaceutical
  • protective agent

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Physcion is traded under.

HS 2914.69Indicative HS code

Quinones, other

World exports in 2024
$162M
−10.1% vs 2023, imports $157M
2019 to 2024
Top exporters
  1. China32.8%
  2. Netherlands29.3%
  3. Japan13.8%
Top importers
  1. United States23.0%
  2. India * partner reported16.1%
  3. Thailand7.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Physcion is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Physcion, based on the data on this page

What is Physcion?

Physcion is a dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6. It has been widely isolated and characterised from both terrestrial and marine sources.

What is the CAS number of Physcion?

The CAS registry number of Physcion is 521-61-9.

What is the molecular formula and weight of Physcion?

The molecular formula of Physcion is C16H12O5 and its molar mass is 284.27 g/mol.

What is Physcion used for?

Known uses and roles of Physcion include building blocks in research and laboratory, screening compounds in research and laboratory, anti-inflammatory agent, antibacterial agent, antifungal agent and 7 more.

Is Physcion hazardous?

Physcion carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Physcion?

Physcion is usually classified under HS code 291469 (Quinones, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Physcion?

CompoundList lists 33 suppliers of Physcion in China, United States, Germany, France and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Physcion?

Suppliers quote Physcion on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Physcion

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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