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Respiratory, allergy and digestive drugs

Enprofylline

Also known as 3-Propylxanthine, 3-n-Propylxanthine, Enprofilina

CAS 41078-02-8Formula C8H10N4O2Molar mass 194.19 g/molEC 255-201-8
GHS signal word: Warning. Pictograms: Harmful or irritant 8 suppliers listed
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Enprofylline chemical structure, C8H10N4O2, CAS 41078-02-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
41078-02-8
Formula
C8H10N4O2
Molar mass
194.19 g/mol
EC number
255-201-8
HS code
293359
Category
Respiratory, allergy and digestive drugs

What is Enprofylline?

Plain description, key identifiers and synonyms

Enprofylline is xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. It has a role as a non-steroidal anti-inflammatory drug, a bronchodilator agent, an anti-arrhythmia drug and an anti-asthmatic drug.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-propyl-7H-purine-2,6-dione
CAS number
41078-02-8 CAS number cross-checked
EC number
255-201-8
Molecular formula
C8H10N4O2
UNII
DT7DT5E518
MDL number
MFCD00043205
InChIKey
SIQPXVQCUCHWDI-UHFFFAOYSA-N
InChI
InChI=1S/C8H10N4O2/c1-2-3-12-6-5(9-4-10-6)7(13)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,13,14)
SMILES (canonical and isomeric)
CCCN1C2=C(C(=O)NC1=O)NC=N2

Synonyms

  • 3-Propylxanthine
  • 3-n-Propylxanthine
  • Enprofilina
  • Enprofyllinum
  • 3,7-Dihydro-3-propyl-1H-purine-2,6-dione
  • 1H-Purine-2,6-dione, 3,7-dihydro-3-propyl-
  • 3-Propyl-3,7-dihydro-purine-2,6-dione
  • 3-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
  • 3-propyl-7H-purine-2,6-dione
  • 3-propyl-3,7-dihydro-1H-purine-2,6-dione
  • Nilyph
  • PDSP1_001019
  • PDSP2_001186
  • 3-Propyl-3,7-dihydro-purine-2,6-dione(enprofylline)
  • Enprofylline (USAN/INN)
  • 3-Propylxanthfine
  • 3,7-Dihydro-3-propyl-1H-purine-2,6-dione, 3-Propylxanthine, D 4028, 3,9-Dihydro-3-propyl-1H-purine-2,6-dione, 3-propyl-1H-purine-2,6(3H,7H)-dione
  • PDSP2
  • 3-Propylxanthine (enprofylline)
  • PDSP1_001202
  • PDSP2_001003
  • Sdccgsbi-0050885.p002

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
194.19 g/molcalc.
Exact mass
194.0804 Dacalc.
LogP (octanol/water)
-0.18calc.
Topological polar surface area
83.54 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
2calc.
Heavy atoms
14calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.38calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1[nH]c(=O)c2[nH]cnc2[nH]1

O=c1[nH]c(=O)c2[nH]cnc2[nH]1

2 rings, 11 atoms, the Xanthine ring system.

1,880 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H332Harmful if inhaled.
Precautionary statements (13)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Enprofylline suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 8 suppliers
8 of 8 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

8 suppliers in 3 countries

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Enprofylline price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Adenosine A2 Receptor Antagonists
  • Anti-Asthmatic Agents
  • Bronchodilator Agents

Roles

  • anti-arrhythmia drug
  • anti-asthmatic agent
  • anti-asthmatic drug
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antirheumatic drug
  • bronchodilator agent
  • cardiovascular drug
  • non-steroidal anti-inflammatory drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Enprofylline is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Enprofylline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Enprofylline, based on the data on this page

What is Enprofylline?

Enprofylline is xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.

What is the CAS number of Enprofylline?

The CAS registry number of Enprofylline is 41078-02-8.

What is the molecular formula and weight of Enprofylline?

The molecular formula of Enprofylline is C8H10N4O2 and its molar mass is 194.19 g/mol.

What is Enprofylline used for?

Known uses and roles of Enprofylline include anti-inflammatories in pharmaceuticals, cardiovascular drugs in pharmaceuticals, respiratory and anti-allergy drugs in pharmaceuticals, anti-arrhythmia drug, anti-asthmatic agent and 11 more.

Is Enprofylline hazardous?

Enprofylline carries the GHS signal word "Warning". Main hazards: harmful if swallowed, harmful in contact with skin, harmful if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Enprofylline?

Enprofylline is usually classified under HS code 293359 (Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Enprofylline?

CompoundList lists 8 suppliers of Enprofylline in United States, China and United Kingdom. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Enprofylline?

Suppliers quote Enprofylline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Enprofylline

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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