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Heterocyclic building blocks

Enterolactone

Also known as Compound 180/442, (3R,4R)-3,4-bis((3-hydroxyphenyl)methyl)tetrahydrofuran-2-one, (+)-Enterolactone

CAS 78473-71-9Formula C18H18O4Molar mass 298.34 g/molEC 634-756-3
GHS signal word: Warning. Pictograms: Harmful or irritant 2 suppliers listed
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Enterolactone chemical structure, C18H18O4, CAS 78473-71-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
78473-71-9
Formula
C18H18O4
Molar mass
298.34 g/mol
EC number
634-756-3
HS code
293220
Category
Heterocyclic building blocks

What is Enterolactone?

Plain description, key identifiers and synonyms

Enterolactone is a lignan.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3S,4S)-3,4-bis[(3-hydroxyphenyl)methyl]oxolan-2-one
CAS number
78473-71-9Other or deprecated CAS: 185254-87-9
EC number
634-756-3
Molecular formula
C18H18O4
UNII
X01E7E1D6H
InChIKey
HVDGDHBAMCBBLR-PBHICJAKSA-N
InChI
InChI=1S/C18H18O4/c19-15-5-1-3-12(8-15)7-14-11-22-18(21)17(14)10-13-4-2-6-16(20)9-13/h1-6,8-9,14,17,19-20H,7,10-11H2/t14-,17+/m1/s1
Canonical SMILES
O=C1OCC(Cc2cccc(O)c2)C1Cc1cccc(O)c1
Isomeric SMILES
C1[C@H]([C@@H](C(=O)O1)CC2=CC(=CC=C2)O)CC3=CC(=CC=C3)O

Synonyms

  • Compound 180/442
  • (3R,4R)-3,4-bis((3-hydroxyphenyl)methyl)tetrahydrofuran-2-one
  • (+)-Enterolactone
  • (3s,4s)-3,4-bis(3-hydroxybenzyl)dihydrofuran-2(3h)-one
  • HBBL
  • Enterolactone, ~95% (HPLC)
  • (3R,4R)-Rel-dihydro-3,4-bis((3-hydroxyphenyl)methyl)-2(3H)-furanone
  • 2(3H)-Furanone, dihydro-3,4-bis((3-hydroxyphenyl)methyl)-, (3R,4R)-rel-
  • (+/-)-Enterolactone, analytical standard
  • trans-2,3-bis(3-hydroxybenzyl) butyrolactone
  • Dihydro-3,4-bis((3-hydroxyphenyl)methyl)-2(3H)-Furanone
  • trans-(+/-)-2,3-Bis(3'-hydroxybenzyl)-gamma-butyrolactone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
298.34 g/molcalc.
Exact mass
298.1205 Dacalc.
LogP (octanol/water)
2.67calc.
Topological polar surface area
66.76 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
22calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.28calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1OCC(Cc2ccccc2)C1Cc1ccccc1

O=C1OCC(Cc2ccccc2)C1Cc1ccccc1

3 rings, 20 atoms.

49 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Enterolactone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 2 suppliers
  • AChemBlock
    United States, HaywardUnclaimed profile
    EnterolactoneGrade, purity and minimum order on request
    Price on request
    View
  • Shenghe Chemical
    China, JinanUnclaimed profile
    EnterolactoneGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

2 suppliers in 2 countries

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Enterolactone price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Enterolactone is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Enterolactone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Enterolactone, based on the data on this page

What is Enterolactone?

Enterolactone is a lignan.

What is the CAS number of Enterolactone?

The CAS registry number of Enterolactone is 78473-71-9. Other or deprecated CAS numbers: 185254-87-9.

What is the molecular formula and weight of Enterolactone?

The molecular formula of Enterolactone is C18H18O4 and its molar mass is 298.34 g/mol.

What is Enterolactone used for?

Known uses and roles of Enterolactone include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Enterolactone hazardous?

Enterolactone carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Enterolactone?

Enterolactone is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Enterolactone?

CompoundList lists 2 suppliers of Enterolactone in China and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Enterolactone?

Suppliers quote Enterolactone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Enterolactone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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