Fialuridine
Also known as FIAU, Fluoroiodoarauridine, 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil
Key facts
What buyers check first
- CAS number
- 69123-98-4
- Formula
- C9H10FIN2O5
- Molar mass
- 372.09 g/mol
- EC number
- 688-476-1
- HS code
- 293499
- Category
- Screening compounds
What is Fialuridine?
Plain description, key identifiers and synonyms
Fialuridine is a nucleoside analog of uridine with activity against hepatitis B virus and herpes viruses. Fialuridine inhibits viral DNA polymerase and viral replication.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
- CAS number
- 69123-98-4 CAS number cross-checked
- EC number
- 688-476-1
- Molecular formula
- C9H10FIN2O5
- UNII
- 53T7IN77LC
- MDL number
- MFCD00866922
- InChIKey
- IPVFGAYTKQKGBM-BYPJNBLXSA-N
- InChI
- InChI=1S/C9H10FIN2O5/c10-5-6(15)4(2-14)18-8(5)13-1-3(11)7(16)12-9(13)17/h1,4-6,8,14-15H,2H2,(H,12,16,17)/t4-,5+,6-,8-/m1/s1
- Canonical SMILES
- O=c1[nH]c(=O)n(C2OC(CO)C(O)C2F)cc1I
- Isomeric SMILES
- C1=C(C(=O)NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F)I
Synonyms
- FIAU
- Fluoroiodoarauridine
- 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil
- Fialuridina
- 2'-Fluoro-5-iodo-1-beta-D-arabinofuranosyluracil
- Uracil, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodo-
- 2'-fluoro-5-iodoarauracil
- 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodo-
- 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione
- fialuridinum
- 1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione
- 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione
- 1-(2'fluoro-2'-deoxyarabinofuranosyl)-5-iodouracil
- 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodo-unracil
- 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
- 1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodouracil
- 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione
- 1-(2-deoxy-2-fluoro-|A-D-arabinofuranosyl)-5-iodouracil
- 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione
- 1-(2'-Deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil
- 2'-Fluoro-5-iodouracil
- Fialuridine (USAN/INN)
- Fialuridine - Bio-X trade mark
- Fialuridine, >=98% (HPLC)
- Uracil, 1-(2-deoxy-2-fluoro-beta-D
Show all 27 synonymsShow fewer synonyms
- 1-(2'-Deoxy-2'-fluoro-?-D-arabinofuranosyl)-5-iodouracil
- 1-(2-Deoxy-2-fluoro-|_-D-arabinofuranosyl)-5-iodouracil
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 372.09 g/molcalc.Computed value |
|---|---|
| Exact mass | 371.9618 Dacalc.Computed value |
| LogP (octanol/water) | -1.27calc.Computed value |
| Topological polar surface area | 104.6 Ųcalc.Computed value |
| Hydrogen bond donors | 3calc.Computed value |
| Hydrogen bond acceptors | 5calc.Computed value |
| Rotatable bonds | 2calc.Computed value |
| Heavy atoms | 18calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0.56calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 4calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=c1ccn(C2CCCO2)c(=O)[nH]1
2 rings, 13 atoms, the Tetrahydrofuryluracil ring system.
3,051 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H301Toxic if swallowed.
- H312Harmful in contact with skin.
- H332Harmful if inhaled.
Precautionary statements (14)
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P316If swallowed: Get emergency medical help immediately.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P317Get medical help.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidFialuridine suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China ManufacturerUnclaimed profileFialuridineGrade, purity and minimum order on requestPrice on request
- China, ZhengzhouUnclaimed profileFialuridineGrade, purity and minimum order on requestPrice on request
- United States, Little Rock ManufacturerUnclaimed profileFiauGrade, purity and minimum order on requestPrice on request
- China, NanjingUnclaimed profileFialuridineGrade, purity and minimum order on requestPrice on request
- United States, HaywardUnclaimed profileFialuridineGrade, purity and minimum order on requestPrice on request
- China, ShanghaiUnclaimed profileFialuridineGrade, purity and minimum order on requestPrice on request
- China, GuangzhouUnclaimed profileFialuridineGrade, purity and minimum order on requestPrice on request
- China, HangzhouUnclaimed profileFialuridineGrade, purity and minimum order on requestPrice on request
- China, KunshanUnclaimed profileFialuridineGrade, purity and minimum order on requestPrice on request
- Czech Republic, Kralupy nad VltavouUnclaimed profileFialuridineGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
11 suppliers in 3 countries
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Fialuridine price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Pharmacological actions
- Antiviral Agents
- Nucleic Acid Synthesis Inhibitors
Roles
- anti-HBV agent
- antimicrobial agent
- antiviral agent
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Fialuridine is traded under.
Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934
- United States24.5%
- Germany23.1%
- Japan4.5%
The HS code shown for Fialuridine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Fialuridine, based on the data on this page
What is Fialuridine?
What is the CAS number of Fialuridine?
What is the molecular formula and weight of Fialuridine?
What is Fialuridine used for?
Is Fialuridine hazardous?
What is the HS code of Fialuridine?
Where can I buy Fialuridine?
What is the price of Fialuridine?
Guides for buyers
Practical guides that help when you source, ship or handle Fialuridine
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
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