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Flavonoids and polyphenols

Ginkgetin

Also known as 7,4'-Dimethylamentoflavone, Amentoflavone 7,4'-dimethyl ether, 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)chromen-4-one

CAS 481-46-9Formula C32H22O10Molar mass 566.52 g/mol
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Ginkgetin chemical structure, C32H22O10, CAS 481-46-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
481-46-9
Formula
C32H22O10
Molar mass
566.52 g/mol
HS code
293299
Category
Flavonoids and polyphenols

What is Ginkgetin?

Plain description, key identifiers and synonyms

Ginkgetin is a biflavonoid that is the 7,4'-dimethyl ether derivative of amentoflavone. Isolated from Ginkgo biloba and Dioon, it exhibits anti-HSV-1, antineoplastic and inhibitory activities towards arachidonate 5-lipoxygenase and cyclooxygenase 2. It has a role as a metabolite, an antineoplastic agent, a cyclooxygenase 2 inhibitor, an anti-HSV-1 agent and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is a hydroxyflavone, a methoxyflavone, a ring assembly and a biflavonoid. It is functionally related to an amentoflavone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)chromen-4-one
CAS number
481-46-9 CAS number cross-checked
Molecular formula
C32H22O10
UNII
HY5EZW8269
MDL number
MFCD09970948
InChIKey
AIFCFBUSLAEIBR-UHFFFAOYSA-N
InChI
InChI=1S/C32H22O10/c1-39-18-10-20(34)30-23(37)13-27(41-28(30)11-18)16-5-8-25(40-2)19(9-16)29-21(35)12-22(36)31-24(38)14-26(42-32(29)31)15-3-6-17(33)7-4-15/h3-14,33-36H,1-2H3
SMILES (canonical and isomeric)
COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)OC)O)C4=C(C=C(C5=C4OC(=CC5=O)C6=CC=C(C=C6)O)O)O

Synonyms

  • 7,4'-Dimethylamentoflavone
  • Amentoflavone 7,4'-dimethyl ether
  • 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)chromen-4-one
  • 4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)-
  • 4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-
  • 5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)chromen-4-one
  • 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-4H-chromen-4-one
  • 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-chromen-2-yl)-2-methoxy-phenyl]-2-(4-hydroxyphenyl)chromen-4-one
  • 5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)-4H-chromen-4-one
  • 5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • Ginkgetin (Standard)
  • Ginkgetin [M+H]+
  • jm5b01461, Compound 89
  • Ginkgetin 7''-O-beta-D-glucopyranoside
  • 3''',8-Biflavone, 4',5,5'',7-tetrahydroxy-4''',7''-dimethoxy-
  • 4''',5,5'',7''-tetrahydroxy-4',7-dimethoxy-(3'->8'')-biflavone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
566.52 g/molcalc.
Exact mass
566.1213 Dacalc.
LogP (octanol/water)
5.74calc.
Topological polar surface area
159.8 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
10calc.
Rotatable bonds
5calc.
Heavy atoms
42calc.
Rings
6calc.
Aromatic rings
6calc.
Fraction sp3 carbons
0.06calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1cc(-c2cccc(-c3cccc4c(=O)cc(-c5ccccc5)oc34)c2)oc2ccccc12

O=c1cc(-c2cccc(-c3cccc4c(=O)cc(-c5ccccc5)oc34)c2)oc2ccccc12

6 rings, 34 atoms.

20 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Ginkgetin suppliers

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Where suppliers are based

4 suppliers in 1 country

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Ginkgetin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • anti-HSV agent
  • anti-HSV-1 agent
  • antimicrobial agent
  • antineoplastic agent
  • antiviral agent
  • cyclooxygenase 2 inhibitor
  • enzyme inhibitor
  • lipoxygenase inhibitor
  • metabolite
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ginkgetin is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ginkgetin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ginkgetin, based on the data on this page

What is Ginkgetin?

Ginkgetin is a biflavonoid that is the 7,4'-dimethyl ether derivative of amentoflavone. Isolated from Ginkgo biloba and Dioon, it exhibits anti-HSV-1, antineoplastic and inhibitory activities towards arachidonate 5-lipoxygenase and cyclooxygenase 2.

What is the CAS number of Ginkgetin?

The CAS registry number of Ginkgetin is 481-46-9.

What is the molecular formula and weight of Ginkgetin?

The molecular formula of Ginkgetin is C32H22O10 and its molar mass is 566.52 g/mol.

What is Ginkgetin used for?

Known uses and roles of Ginkgetin include anti-hsv agent, anti-hsv-1 agent, antimicrobial agent, antineoplastic agent, antiviral agent and 5 more.

Is Ginkgetin hazardous?

No GHS hazard classification for Ginkgetin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Ginkgetin?

Ginkgetin is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ginkgetin?

CompoundList lists 4 suppliers of Ginkgetin in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ginkgetin?

Suppliers quote Ginkgetin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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