Halazepam
Also known as Paxipam, Pacinone, Sch 12041
Key facts
What buyers check first
- CAS number
- 23092-17-3
- Formula
- C17H12ClF3N2O
- Molar mass
- 352.74 g/mol
- EC number
- 245-425-4
- HS code
- 293391
- Category
- Central nervous system drugs
What is Halazepam?
Plain description, key identifiers and synonyms
Halazepam is an organic molecular entity.
Halazepam is a benzodiazepine seditative.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-2-one
- CAS number
- 23092-17-3 CAS number cross-checked
- EC number
- 245-425-4
- Molecular formula
- C17H12ClF3N2O
- UNII
- 320YC168LF
- InChIKey
- WYCLKVQLVUQKNZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H12ClF3N2O/c18-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)22-9-15(24)23(14)10-17(19,20)21/h1-8H,9-10H2
- SMILES (canonical and isomeric)
- C1C(=O)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3)CC(F)(F)F
Synonyms
- Paxipam
- Pacinone
- Sch 12041
- Halazepamum
- Halazepam civ
- 7-Chloro-1,3-dihydro-5-phenyl-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-one
- Alapryl
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-1-(2,2,2-trifluoroethyl)-
- 7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one
- alazepam
- Schering 12041
- 7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-2-one
- 7-Chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-
- Halazepam (1.0mg/ml in Acetonitrile)
- Paxipam (TN)
- Halazepam (USAN/INN)
- Halezepam
- DEA No. 2762
- 5-24-04-00303 (Beilstein Handbook Reference)
- Halazepam (1 mg/ml in Acetonitrile)
- 7-Chloro-5-phenyl-1-(2,2,2-trifluorethyl)-1H-1,4-benzodiazepin-2(3H)-on
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 352.74 g/molcalc.Computed value |
|---|---|
| Exact mass | 352.059 Dacalc.Computed value |
| LogP (octanol/water) | 4.09calc.Computed value |
| Topological polar surface area | 32.67 Ųcalc.Computed value |
| Hydrogen bond donors | 0calc.Computed value |
| Hydrogen bond acceptors | 2calc.Computed value |
| Rotatable bonds | 2calc.Computed value |
| Heavy atoms | 24calc.Computed value |
| Rings | 3calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.18calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=C1CN=C(c2ccccc2)c2ccccc2N1
3 rings, 18 atoms, the RO-05-2921 ring system.
540 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H315Causes skin irritation.
- H317May cause an allergic skin reaction.
- H319Causes serious eye irritation.
- H411Toxic to aquatic life with long lasting effects.
- H412Harmful to aquatic life with long lasting effects.
Precautionary statements (15)
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P272Contaminated work clothing should not be allowed out of the workplace.
- P273Avoid release to the environment.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P302 + P352If on skin: Wash with plenty of water.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P332 + P317If skin irritation occurs: Get medical help.
- P333 + P317If skin irritation or rash occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P391Collect spillage.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidHalazepam suppliers
Trading restrictions apply to this substance
Halazepam is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.
Listing and enquiries are not allowed for this substance.
Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2933.91 (benzodiazepines and related substances)
Our policy on controlled substancesHalazepam price
Indicative price range per kg from live supplier offers
Prices are not shown for prohibited substances.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Pharmacological actions
- Anti-Anxiety Agents
Roles
- anxiolytic drug
- central nervous system depressant
- central nervous system drug
- pharmaceutical
- psychotropic drug
- tranquilizing drug
Pharmacology
Halazepam is a synthetic benzodiazepine derivative with anxiolytic property. Halazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the benzodiazepine-GABA-A-chloride ionophore receptor complex located in the limbic, thalamic, and hypothalamic regions of the central nervous system (CNS). This increases the frequency of chloride channel opening, allowing the flow of chloride ions into the neuron and ultimately leading to membrane hyperpolarization and a decrease in neuronal excitability.
Regulatory status
Inventories, regulations and trade controls that list this substance
Halazepam is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.
Listing and enquiries are not allowed for this substance.
Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2933.91 (benzodiazepines and related substances)
Our policy on controlled substancesControls
- US DEA controlled substance or listed chemical
- Controlled psychotropic substance
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Halazepam is traded under.
Alprazolam (INN), camazepam (INN), chlordiazepoxide (INN), clonazepam (INN)…
- Italy37.7%
- United States22.7%
- India * partner reported9.8%
- Germany13.8%
- Spain10.4%
- United States10.2%
* Partner reported figures, a lower bound.
The HS code shown for Halazepam is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.
Related chemicals
Parent and salt forms, stereoisomers, similar structures and isomers
Similar structures
Nearest neighbours by Morgan fingerprint Tanimoto similarity
Same formula isomers
Different compounds that share this molecular formula
![4-(4-Chlorophenyl)-5-methyl-2-[3-(trifluoromethyl)phenyl]-1,2-dihydro-3H-pyrazol-3-one chemical structure, C17H12ClF3N2O, CAS 400076-57-5](/s/XTXKUSRZJFEIQB-UHFFFAOYSA-N.svg)
![4-(3-Chlorophenyl)-5-methyl-2-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-one chemical structure, C17H12ClF3N2O, CAS 400076-59-7](/s/CDTFJQYRWAWYIM-UHFFFAOYSA-N.svg)
![4-(4-Chlorophenyl)-6-[4-(trifluoromethyl)phenyl]-4,5-dihydro-3(2H)-pyridazinone chemical structure, C17H12ClF3N2O, CAS 478260-86-5](/s/FVLUIFVPHFBBIK-UHFFFAOYSA-N.svg)
![2-Chloro-N-{2-[3-(trifluoromethyl)phenyl]-2,3-dihydro-1H-isoindol-1-ylidene}acetamide chemical structure, C17H12ClF3N2O, CAS 565194-88-9](/s/MOWUIEGIHKBFBV-UHFFFAOYSA-N.svg)
![8-Chloro-N-[2-methyl-4-(trifluoromethoxy)phenyl]-2-quinolinamine chemical structure, C17H12ClF3N2O, CAS 1258453-79-0](/s/DMGALOCEQNYOHP-UHFFFAOYSA-N.svg)
![3-(2-Chloroethyl)-1-[3-(trifluoromethyl)phenyl]-1,8-naphthyridin-2-one chemical structure, C17H12ClF3N2O, CAS 135634-30-9](/s/DJNJTPHEGZWTMT-UHFFFAOYSA-N.svg)
Frequently asked questions
Quick answers about Halazepam, based on the data on this page
What is Halazepam?
What is the CAS number of Halazepam?
What is the molecular formula and weight of Halazepam?
What is Halazepam used for?
Is Halazepam hazardous?
What is the HS code of Halazepam?
Can I buy Halazepam on CompoundList?
Guides for buyers
Practical guides that help when you source, ship or handle Halazepam
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
Explore more in Central nervous system drugs or HS code 293391