(+)-Menthol
Also known as d-Menthol, (1S,2R,5S)-(+)-Menthol, (1S,2R,5S)-Menthol
Key facts
What buyers check first
- Physical form
- Crystals
- Melting point
- 37.8 °C
- Boiling point
- 216.1 °C
- Density
- 0.904 at 59 °F - Less dense than water, will float
- Flash point
- 91.1 °C
- HS code
- 290611
- Category
- Pharmaceuticals and APIs

What is (+)-Menthol?
Plain description, key identifiers and synonyms
(+)-menthol is a p-menthan-3-ol which has (1S,2R,5S)-stereochemistry. In contrast to ()-menthol, the (+)-enantiomer occurs only rarely in nature. It is an enantiomer of a (-)-menthol.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (1S,2R,5S)-5-methyl-2-propan-2-ylcyclohexan-1-ol
- CAS number
- 15356-60-2 CAS number cross-checkedOther or deprecated CAS: 15356-70-4, 89-78-1
- EC numbers
- 239-387-8, 239-388-3
- Molecular formula
- C10H20O
- UNII
- C6B1OE8P3W
- MDL number
- MFCD00062983
- InChIKey
- NOOLISFMXDJSKH-AEJSXWLSSA-N
- InChI
- InChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m0/s1
- Canonical SMILES
- CC1CCC(C(C)C)C(O)C1
- Isomeric SMILES
- C[C@H]1CC[C@@H]([C@H](C1)O)C(C)C
Synonyms
- d-Menthol
- (1S,2R,5S)-(+)-Menthol
- (1S,2R,5S)-Menthol
- (1S,2R,5S)-2-Isopropyl-5-methylcyclohexanol
- Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1S,2R,5S)-
- Menthol, (+)-
- Menthol, (1S,3S,4R)-(+)-
- (+)-(1S,2R,5S)-menthol
- (+)-(1S,3S,4R)-menthol
- Menthol, d-
- Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1S-(1alpha,2beta,5alpha))-
- Cryomax Cooling
- (+)menthol
- (1S,2R,5S)Menthol
- (1S,2R,5S)(+)Menthol
- 5% Menthol Pain Relief Patch
- Menthol, (1S,3S,4R)(+)
- Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1S-(1alpha,2beta,5alpha)]-
- (1S,2R,5S)2Isopropyl5methylcyclohexanol
- (1S,2R)-5-methyl-2-propan-2-ylcyclohexan-1-ol
- 5% Menthol Pain Relief Patch (2 Patches/Pouch)
- Cyclohexanol, 5methyl2(1methylethyl), (1S,2R,5S)
- 5% Menthol Pain Relief Patch (1 Large Patch/Pouch)
- Cyclohexanol, 5methyl2(1methylethyl), (1S(1alpha,2beta,5alpha))
- MyDerm Pro Freeze spot stick concentrated pain relief formula 15.75 menthol
Show all 38 synonymsShow fewer synonyms
- (1S,2R,5S)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol
- (1S,2R,5S)-5-methyl-2-propan-2-ylcyclohexan-1-ol
- Hexahydrothymol
- rac-Menthol
- (1S,2R,5S)-2-Isopropyl-5-methylcyclohexan-1-ol
- (+)-p-Menthan-3-ol
- Racemic menthol
- 3-p-Menthanol
- Menthol, cis-1,3,trans-1,4-
- Fancol menthol
- Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1alpha,2beta,5alpha)-
- (1S,3S,4R)-p-Menthane-3-ol
- (DL)-Menthol
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Physical form | Crystalsexp.Measured value |
|---|---|
| Melting point | 37.8 °Cexp.Measured value |
| Boiling point | 216.1 °Cexp.Measured value |
| Density | 0.904 at 59 °F - Less dense than water, will floatexp.Measured value |
| Flash point | 91.1 °Cexp.Measured value |
| Solubility | Less than 1 mg/mL at 70 °Fexp.Measured value |
| Vapour pressure | 1 mmHg at 133 °F approximatelyexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 156.27 g/molcalc.Computed value |
|---|---|
| Exact mass | 156.1514 Dacalc.Computed value |
| LogP (octanol/water) | 2.44calc.Computed value |
| Topological polar surface area | 20.23 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 1calc.Computed value |
| Rotatable bonds | 1calc.Computed value |
| Heavy atoms | 11calc.Computed value |
| Rings | 1calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 1calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 3calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H315Causes skin irritation.
Precautionary statements (6)
- P264Wash skin thoroughly after handling.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P302 + P352If on skin: Wash with plenty of water.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P332 + P317If skin irritation occurs: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aid(+)-Menthol suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, SuzhouUnclaimed profile(+)-MentholGrade, purity and minimum order on requestPrice on request
- United States, FriscoUnclaimed profile(+)-MentholGrade, purity and minimum order on requestPrice on request
- Price on request
- United States, HatfieldUnclaimed profile(+)-MentholGrade, purity and minimum order on requestPrice on request
- United States, AlachuaUnclaimed profile(+)-MentholGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
5 suppliers in 2 countries
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(+)-Menthol price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industrial uses: Odor agents, Fragrance.
Consumer uses: Fragrance.
Industries and functions
Functional uses
- Fragrance
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code (+)-Menthol is traded under.
Menthol
- India * partner reported21.3%
- China17.9%
- United States10.9%
* Partner reported figures, a lower bound.
The HS code shown for (+)-Menthol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about (+)-Menthol, based on the data on this page
What is (+)-Menthol?
What is the CAS number of (+)-Menthol?
What is the molecular formula and weight of (+)-Menthol?
What is (+)-Menthol used for?
Is (+)-Menthol hazardous?
What is the HS code of (+)-Menthol?
Where can I buy (+)-Menthol?
What is the price of (+)-Menthol?
Guides for buyers
Practical guides that help when you source, ship or handle (+)-Menthol
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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