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Amines and amides

Norfenefrine

Also known as 3-(2-Amino-1-hydroxyethyl)phenol, Norphenylephrine, m-Octopamine

CAS 536-21-0Formula C8H11NO2Molar mass 153.18 g/molEC 208-626-8
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Norfenefrine chemical structure, C8H11NO2, CAS 536-21-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
536-21-0
Formula
C8H11NO2
Molar mass
153.18 g/mol
EC number
208-626-8
HS code
292250
Category
Amines and amides

What is Norfenefrine?

Plain description, key identifiers and synonyms

Norfenefrine is a member of phenols.

Norfenefrine is a trace amine neuromodulator (meta-octopamine) and pharmaceutical drug.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-(2-amino-1-hydroxyethyl)phenol
CAS number
536-21-0 CAS number cross-checkedOther or deprecated CAS: 15308-34-6
EC number
208-626-8
Molecular formula
C8H11NO2
UNII
D2P3M6SRN5
MDL number
MFCD00012879
InChIKey
LRCXRAABFLIVAI-UHFFFAOYSA-N
InChI
InChI=1S/C8H11NO2/c9-5-8(11)6-2-1-3-7(10)4-6/h1-4,8,10-11H,5,9H2
SMILES (canonical and isomeric)
C1=CC(=CC(=C1)O)C(CN)O

Synonyms

  • 3-(2-Amino-1-hydroxyethyl)phenol
  • Norphenylephrine
  • m-Octopamine
  • Norfenefrina
  • Norfenefrinum
  • m-Hydroxyphenylethanolamine
  • 1-(m-Hydroxyphenyl)-2-aminoethanol
  • (+-)-Norphenylephrine
  • WV569 FREE BASE
  • WV-569 FREE BASE
  • 3-octopamine
  • alpha-(aminomethyl)-3-hydroxybenzyl alcohol
  • Norphenephrine
  • Metacardiol
  • Normetol
  • Norenol
  • DL-Norphenylephrine
  • R,S-Norphenylephrine
  • DL-Norphenylephrine Hydrochloride
  • alpha-(Aminomethyl)-m-hydroxybenzyl alcohol
  • 1-(3'-Hydroxyphenyl)-2-aminoethanol
  • 1-(3-Hydroxyphenyl)-1-hydroxy-2-aminoethane
  • Normezaton, Norphenephrine
  • Normetasympathol
  • BENZYL ALCOHOL, alpha-(AMINOMETHYL)-m-HYDROXY-
Show all 35 synonyms
  • Norfenefrine (INN)
  • 2-amino-1-(3-hydroxyphenyl)ethan-1-ol
  • DL-m-Octopamine
  • Benzenemethanol, alpha-(aminomethyl)-3-hydroxy-
  • WV 569 [as hydrochloride]
  • 3-(2-Amino-1-hydroxy-ethyl)-phenol
  • benzene, 1-(2-amino-1-hydroxy)ethyl-3-hydroxy-
  • Norfenefrin
  • (r)-3-(2-Amino-1-hydroxyethyl)phenol
  • (+-)-alpha-(Aminomethyl)-m-hydroxybenzyl alcohol

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
153.18 g/molcalc.
Exact mass
153.079 Dacalc.
LogP (octanol/water)
0.38calc.
Topological polar surface area
66.48 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
2calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.25calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Norfenefrine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 4 suppliers
4 of 4 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

4 suppliers in 4 countries

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Norfenefrine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Adrenergic alpha-Agonists

Roles

  • cardiovascular drug
  • pharmaceutical

Functional uses

  • Pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Norfenefrine is traded under.

HS 2922.50Indicative HS code

Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function

World exports in 2024
$3.29B
−5.9% vs 2023, imports $3.19B
2019 to 2024
Top exporters
  1. China39.2%
  2. United Kingdom27.1%
  3. India * partner reported4.8%
Top importers
  1. United States20.7%
  2. Germany7.6%
  3. Italy6.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Norfenefrine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Norfenefrine, based on the data on this page

What is Norfenefrine?

Norfenefrine is a member of phenols.

What is the CAS number of Norfenefrine?

The CAS registry number of Norfenefrine is 536-21-0. Other or deprecated CAS numbers: 15308-34-6.

What is the molecular formula and weight of Norfenefrine?

The molecular formula of Norfenefrine is C8H11NO2 and its molar mass is 153.18 g/mol.

What is Norfenefrine used for?

Use classes: Pharmaceuticals.

Is Norfenefrine hazardous?

No GHS hazard classification for Norfenefrine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Norfenefrine?

Norfenefrine is usually classified under HS code 292250 (Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Norfenefrine?

CompoundList lists 4 suppliers of Norfenefrine in Germany, Hong Kong, Singapore and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Norfenefrine?

Suppliers quote Norfenefrine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Norfenefrine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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