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Central nervous system drugs

Oxazepam

Also known as Serax, Tazepam, Adumbran

CAS 604-75-1Formula C15H11ClN2O2Molar mass 286.72 g/molEC 210-076-9
GHS signal word: Warning. Pictograms: Serious health hazard Prohibited, not for trade Drug substance
Why it is not for trade
Oxazepam chemical structure, C15H11ClN2O2, CAS 604-75-1
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from alcohol
Melting point
205 to 206
Solubility
1 G SOL IN MORE THAN 10,000 ML WATER, 220 ML ALCOHOL, 270 ML CHLOROFORM, 2200 ML ETHER
HS code
293391
Category
Central nervous system drugs

What is Oxazepam?

Plain description, key identifiers and synonyms

Oxazepam is a 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5. It has a role as an anxiolytic drug, a xenobiotic and an environmental contaminant. It is a 1,4-benzodiazepinone and an organochlorine compound.

Oxazepam is a benzodiazepine seditative.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
CAS number
604-75-1 CAS number cross-checked
EC number
210-076-9
Molecular formula
C15H11ClN2O2
UNII
6GOW6DWN2A
MDL number
MFCD00057903
InChIKey
ADIMAYPTOBDMTL-UHFFFAOYSA-N
InChI
InChI=1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19)
SMILES (canonical and isomeric)
C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O

Synonyms

  • Serax
  • Tazepam
  • Adumbran
  • Droxacepam
  • Rondar
  • Serenid
  • Serepax
  • Seresta
  • Sobril
  • Zaxopam
  • Ansioxacepam
  • Durazepam
  • Noctazepam
  • Psiquiwas
  • Quilibrex
  • Anxiolit
  • Aplakil
  • Astress
  • Drimuel
  • Limbial
  • Murelax
  • Nesontil
  • Pacienx
  • Praxiten
  • Sigacalm
Show all 39 synonyms
  • Bonare
  • Isodin
  • Propax
  • Serpax
  • Vaben
  • Hi-Long
  • Psicopax
  • (RS)-Oxazepam
  • Nortemazepam
  • Tarchomin
  • Nozepam
  • Serenid-D
  • (+-)-Oxazepam
  • Oxazepamum

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from alcoholexp.
Odour
PRACTICALLY ODORLESSexp.
Taste
BITTERexp.
Melting point
205 to 206exp.
Solubility
1 G SOL IN MORE THAN 10,000 ML WATER, 220 ML ALCOHOL, 270 ML CHLOROFORM, 2200 ML ETHERexp.
Vapour pressure
4.2 × 10⁻¹² mm Hg at 25 °C /Estimated/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
286.72 g/molcalc.
Exact mass
286.0509 Dacalc.
LogP (octanol/water)
2.45calc.
Topological polar surface area
61.69 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
1calc.
Heavy atoms
20calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.07calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CN=C(c2ccccc2)c2ccccc2N1

O=C1CN=C(c2ccccc2)c2ccccc2N1

3 rings, 18 atoms, the RO-05-2921 ring system.

540 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H351Suspected of causing cancer.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Oxazepam suppliers

Trading restrictions apply to this substance

Psychotropic substance

Oxazepam is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2933.91 (benzodiazepines and related substances)

Our policy on controlled substances

Oxazepam price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Medication: anxiolytic.

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Anti-Anxiety Agents
  • GABA Modulators
  • Hypnotics and Sedatives

Roles

  • anti-HIV agent
  • antidepressant
  • antimicrobial agent
  • antipsychotic agent
  • antiviral agent
  • anxiolytic drug
  • central nervous system depressant
  • central nervous system drug
  • environmental contaminant
  • pharmaceutical
  • psychotropic drug
  • tranquilizing drug
  • xenobiotic

Pharmacology

Oxazepam is a Benzodiazepine.

How it is made

2-Amino-5-chlorobenzophenone is acylated with chloroacetyl chloride & the product is refluxed with sodium iodide to form the iodoacetamido compound. Reaction of one with hydroxylamine effects dehydration & dehydrohalogenation to form the benzodiazepine derivative. Treatment of two with acetic anhydride causes rearrangement to oxazepam which is simultaneously esterified to acetate. Saponification liberates oxazepam.

Regulatory status

Inventories, regulations and trade controls that list this substance

Psychotropic substance

Oxazepam is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2933.91 (benzodiazepines and related substances)

Our policy on controlled substances

Controls

  • US DEA controlled substance or listed chemical
  • Controlled psychotropic substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Oxazepam is traded under.

HS 2933.91Exact HS code

Alprazolam (INN), camazepam (INN), chlordiazepoxide (INN), clonazepam (INN)…

World exports in 2024
$118M
−26.3% vs 2023, imports $94.2M
2019 to 2024
Top exporters
  1. Italy37.7%
  2. United States22.7%
  3. India * partner reported9.8%
Top importers
  1. Germany13.8%
  2. Spain10.4%
  3. United States10.2%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Oxazepam is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Oxazepam, based on the data on this page

What is Oxazepam?

Oxazepam is a 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5. It has a role as an anxiolytic drug, a xenobiotic and an environmental contaminant.

What is the CAS number of Oxazepam?

The CAS registry number of Oxazepam is 604-75-1.

What is the molecular formula and weight of Oxazepam?

The molecular formula of Oxazepam is C15H11ClN2O2 and its molar mass is 286.72 g/mol.

What is Oxazepam used for?

Medication: anxiolytic. Use classes: Pharmaceuticals.

Is Oxazepam hazardous?

Oxazepam carries the GHS signal word "Warning". Main hazards: suspected of causing cancer. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Oxazepam?

Oxazepam is usually classified under HS code 293391 (Alprazolam (INN), camazepam (INN), chlordiazepoxide (INN), clonazepam (INN)…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Oxazepam on CompoundList?

No. Oxazepam is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Oxazepam

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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