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Analgesics and anti-inflammatories

Oxycodone hydrochloride

Also known as Oxycodone Hcl, Oxecta, Endocodone

CAS 124-90-3Formula C18H22ClNO4Molar mass 351.83 g/molEC 204-717-1
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard Prohibited, not for trade Drug substance
Why it is not for trade
Oxycodone hydrochloride chemical structure, C18H22ClNO4, CAS 124-90-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
124-90-3
Formula
C18H22ClNO4
Molar mass
351.83 g/mol
EC number
204-717-1
HS code
293499
Category
Analgesics and anti-inflammatories

What is Oxycodone hydrochloride?

Plain description, key identifiers and synonyms

Oxycodone hydrochloride is a hydrochloride obtained by reaction of oxycodone with one molar equivalent of hydrochloric acid. It is a moderately potent opioid analgesic, generally used for relief of moderate to severe pain. It has a role as an opioid analgesic, an antitussive and a mu-opioid receptor agonist. It contains an oxycodone(1+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(4R,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one, hydrochloride
CAS number
124-90-3 CAS number cross-checked
EC number
204-717-1
Molecular formula
C18H22ClNO4
UNII
C1ENJ2TE6C
InChIKey
MUZQPDBAOYKNLO-RKXJKUSZSA-N
InChI
InChI=1S/C18H21NO4.ClH/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10;/h3-4,13,16,21H,5-9H2,1-2H3;1H/t13-,16+,17+,18-;/m1./s1
Canonical SMILES
COc1ccc2c3c1OC1C(=O)CCC4(O)C(C2)N(C)CCC314.Cl
Isomeric SMILES
CN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)OC)O4)O.Cl

Synonyms

  • Oxycodone Hcl
  • Oxecta
  • Endocodone
  • Roxicodone
  • Dihydrone hydrochloride
  • Dihydrooxycodeinone hydrochloride
  • Oxycodone hydrochloride cii
  • Oxynorm
  • Dihydroxycodeinone hydrochloride
  • Roxybond
  • 14-Hydroxydihydrocodeinone hydrochloride
  • Anhydrous oxycodone hydrochloride
  • 4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one hydrochloride
  • Targiniq component oxycodone hydrochloride
  • Troxyca component oxycodone hydrochloride
  • Xartemis component oxycodone hydrochloride
  • Carexil
  • Leveraxo
  • Longtec
  • Oxeltra
  • Reltebon
  • Shortec
  • Zomestine
  • Abtard
  • Candox
Show all 38 synonyms
  • Lynlor
  • Dolocodon pr
  • Oxycodone Hydchloride
  • Oxycodone HCl Controlled-release
  • Oxycodone Hydrochloride Oral Solution
  • Oxycodone Hydrochloride Controlled-release
  • Oxaydo
  • Oxycontin
  • Oxycodone Hydrochloride (1.0mg/ml in Methanol)
  • Roxicodone (TN)
  • Oxycontin (TN)
  • Oxecta (TN)
  • oxycodone monohydrochloride

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
351.83 g/molcalc.
Exact mass
351.1237 Dacalc.
LogP (octanol/water)
1.47calc.
Topological polar surface area
59 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
1calc.
Heavy atoms
24calc.
Rings
5calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.61calc.
Formal charge
0calc.
Stereocentres
4calc.
Components
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCC2C3Cc4cccc5c4C2(CCN3)C1O5

O=C1CCC2C3Cc4cccc5c4C2(CCN3)C1O5

5 rings, 19 atoms.

148 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H317May cause an allergic skin reaction.
  • H332Harmful if inhaled.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statements (20)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403Store in a well-ventilated place.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Oxycodone hydrochloride suppliers

Trading restrictions apply to this substance

Controlled or monitored substance

Oxycodone hydrochloride is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Our policy on controlled substances

Oxycodone hydrochloride price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Roles

  • agonist
  • analgesic
  • antitussive
  • mu-opioid agent
  • mu-opioid receptor agonist
  • neurotransmitter agent
  • opioid agent
  • opioid analgesic
  • opioid receptor agonist
  • pharmaceutical

Pharmacology

Oxycodone Hydrochloride is the hydrochloride salt of oxycodone, a methylether of oxymorphone and semisynthetic opioid agonist with analgesic and antitussive properties. Oxycodone binds to mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. In addition to analgesia and a depressive effect on the cough center in the medulla, this agent may cause euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, and respiratory depression, depending on dosage and variations in individual metabolism.

Regulatory status

Inventories, regulations and trade controls that list this substance

Controlled or monitored substance

Oxycodone hydrochloride is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Our policy on controlled substances

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Oxycodone hydrochloride is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Oxycodone hydrochloride is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Oxycodone hydrochloride, based on the data on this page

What is Oxycodone hydrochloride?

Oxycodone hydrochloride is a hydrochloride obtained by reaction of oxycodone with one molar equivalent of hydrochloric acid. It is a moderately potent opioid analgesic, generally used for relief of moderate to severe pain. It has a role as an opioid analgesic, an antitussive and a mu-opioid receptor agonist.

What is the CAS number of Oxycodone hydrochloride?

The CAS registry number of Oxycodone hydrochloride is 124-90-3.

What is the molecular formula and weight of Oxycodone hydrochloride?

The molecular formula of Oxycodone hydrochloride is C18H22ClNO4 and its molar mass is 351.83 g/mol.

What is Oxycodone hydrochloride used for?

Known uses and roles of Oxycodone hydrochloride include analgesics and antipyretics in pharmaceuticals, agonist, analgesic, antitussive, mu-opioid agent and 6 more.

Is Oxycodone hydrochloride hazardous?

Oxycodone hydrochloride carries the GHS signal word "Danger". Main hazards: harmful if swallowed, may cause an allergic skin reaction, harmful if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Oxycodone hydrochloride?

Oxycodone hydrochloride is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Oxycodone hydrochloride on CompoundList?

No. Oxycodone hydrochloride is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Oxycodone hydrochloride

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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