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Central nervous system drugs

Pridinol

Also known as 1,1-diphenyl-3-(piperidin-1-yl)propan-1-ol, Nonplesin, Parks

CAS 511-45-5Formula C20H25NOMolar mass 295.43 g/molEC 208-128-0
2 suppliers listed
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Pridinol chemical structure, C20H25NO, CAS 511-45-5
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals
Melting point
120 to 121 °C
Solubility
MW: 391.52. Crystals, mp 152.5-155.0 °C. Sparingly sol in water /Methanesulfonate/
HS code
293339
Category
Central nervous system drugs
Illustrative photo, closed white HDPE bottles and amber jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Pridinol?

Plain description, key identifiers and synonyms

Pridinol is a piperidine substituted at position 1 by a 3-hydroxy-3,3-diphenylpropyl group. It has a role as an antiparkinson drug and a muscle relaxant. It is a member of piperidines and a tertiary alcohol.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,1-diphenyl-3-piperidin-1-ylpropan-1-ol
CAS number
511-45-5 CAS number cross-checked
EC number
208-128-0
Molecular formula
C20H25NO
UNII
9E75Q6SUUB
MDL number
MFCD00242961
InChIKey
RQXCLMGKHJWMOA-UHFFFAOYSA-N
InChI
InChI=1S/C20H25NO/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21/h1-2,4-7,10-13,22H,3,8-9,14-17H2
SMILES (canonical and isomeric)
C1CCN(CC1)CCC(C2=CC=CC=C2)(C3=CC=CC=C3)O

Synonyms

  • 1,1-diphenyl-3-(piperidin-1-yl)propan-1-ol
  • Nonplesin
  • Parks
  • Parks 12 hommel
  • Pridinolum
  • Ridinol
  • Parks 12
  • 1,1-Diphenyl-3-(1-piperidyl)-1-propanol
  • HH 212
  • 1-Piperidinepropanol, alpha,alpha-diphenyl-
  • 3-(N-Piperidyl)-1,1-diphenyl-1-propanol
  • 1,1-Diphenyl-3-piperidino-1-propanol
  • alpha,alpha-Diphenyl-1-piperidinepropanol
  • Benzhydrol, alpha-(2-piperidinoethyl)-
  • pridinolo
  • 3-piperidino-1,1-diphenylpropanol
  • 3-piperidinyl-1,1-diphenylpropan-1-ol
  • Lyseen
  • Nonpressin (free base)
  • 1,1-diphenyl-3-piperidin-1-ylpropan-1-ol
  • Pridinol (INN)
  • 1,1-Diphenyl-3-(1-piperidinyl)-1-propanol
  • 1-Piperidinepropanol,alpha-diphenyl-
  • 5-20-02-00247 (Beilstein Handbook Reference)
  • DivK1c_000726

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystalsexp.
Melting point
120 to 121 °Cexp.
Solubility
MW: 391.52. Crystals, mp 152.5-155.0 °C. Sparingly sol in water /Methanesulfonate/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
295.43 g/molcalc.
Exact mass
295.1936 Dacalc.
LogP (octanol/water)
3.8calc.
Topological polar surface area
23.47 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
5calc.
Heavy atoms
22calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(C(CCN2CCCCC2)c2ccccc2)cc1

c1ccc(C(CCN2CCCCC2)c2ccccc2)cc1

3 rings, 21 atoms, the Fenpiprane ring system.

64 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Pridinol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 2 suppliers
  • DSL Chemicals Co., Ltd.
    China, ShanghaiUnclaimed profile
    PridinolGrade, purity and minimum order on request
    Price on request
    View
  • Specs
    Netherlands, ZoetermeerUnclaimed profile
    PridinolGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

2 suppliers in 2 countries

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Pridinol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Therapeutic category: Antiparkinsonian, muscle relaxant (skeletal).

Use classes: Pharmaceuticals.

Industries and functions

Roles

  • antidyskinesia agent
  • antiparkinson drug
  • muscle relaxant
  • neuromuscular agent
  • pharmaceutical

Pharmacology

Pridinol is an orally bioavailable, blood-brain permeable muscarinic receptor antagonist, with muscle-relaxing and antiparkinsonian activity. Upon oral administration, pridinol targets, binds to and blocks muscarinic receptors located on postganglionic parasympathetic nerve endings and on smooth muscle cells. This blocks the activity of acetylcholine (ACh) and causes its muscle relaxant effects. This may relief involuntary movements, spasms and muscle stiffness in Parkinson's disease and other neuromuscular disorders.

How it is made

Pridinol can be prepared by Grignard reaction of ethyl 3-piperidinopropionate with phenylmagnesium bromide.

May be prepared from ethyl 1-piperidinepropionate and phenylmagnesium bromide

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Pridinol is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Pridinol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Pridinol, based on the data on this page

What is Pridinol?

Pridinol is a piperidine substituted at position 1 by a 3-hydroxy-3,3-diphenylpropyl group. It has a role as an antiparkinson drug and a muscle relaxant. It is a member of piperidines and a tertiary alcohol.

What is the CAS number of Pridinol?

The CAS registry number of Pridinol is 511-45-5.

What is the molecular formula and weight of Pridinol?

The molecular formula of Pridinol is C20H25NO and its molar mass is 295.43 g/mol.

What is Pridinol used for?

Therapeutic category: Antiparkinsonian, muscle relaxant (skeletal). Use classes: Pharmaceuticals.

Is Pridinol hazardous?

No GHS hazard classification for Pridinol is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Pridinol?

Pridinol is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Pridinol?

CompoundList lists 2 suppliers of Pridinol in China and Netherlands. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Pridinol?

Suppliers quote Pridinol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Pridinol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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