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Insecticides and acaricides

Pyrifluquinazon

Also known as pyrifluquinazone, 1-acetyl-3,4-dihydro-3-[(3-pyridinylmethyl)amino]-6-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-2(1h)-quinazolinone, 1-Acetyl-1,2,3,4-tetrahydro-3-((3-pyridylmethyl)amino)-6-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)quinazolin-2-one

CAS 337458-27-2Formula C19H15F7N4O2Molar mass 464.34 g/molEC 812-436-6
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Hazardous to the environment 4 suppliers listed
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Pyrifluquinazon chemical structure, C19H15F7N4O2, CAS 337458-27-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
337458-27-2
Formula
C19H15F7N4O2
Molar mass
464.34 g/mol
EC number
812-436-6
HS code
293359
Category
Insecticides and acaricides

What is Pyrifluquinazon?

Plain description, key identifiers and synonyms

Pyrifluquinazon is a member of the class of quinazolines that is 3,4-dihydroquinazolin-2-one which is substituted at positions 1, 4, and 6 by acetyl, pyridin-3-ylmethyl, and perfluoroisopropyl groups, respectively. An insecticide used to control sucking and chewing pests by disturbing their coordination and ability to feed. It has a role as a TRPV channel modulator, an insecticide and an agrochemical. It is a member of acetamides, a member of pyridines, an organofluorine compound and a member of quinazolines.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-acetyl-6-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-3-(pyridin-3-ylmethylamino)-4H-quinazolin-2-one
CAS number
337458-27-2 CAS number cross-checked
EC number
812-436-6
Molecular formula
C19H15F7N4O2
UNII
KKS8BX5SNW
InChIKey
MIOBBYRMXGNORL-UHFFFAOYSA-N
InChI
InChI=1S/C19H15F7N4O2/c1-11(31)30-15-5-4-14(17(20,18(21,22)23)19(24,25)26)7-13(15)10-29(16(30)32)28-9-12-3-2-6-27-8-12/h2-8,28H,9-10H2,1H3
SMILES (canonical and isomeric)
CC(=O)N1C2=C(CN(C1=O)NCC3=CN=CC=C3)C=C(C=C2)C(C(F)(F)F)(C(F)(F)F)F

Synonyms

  • pyrifluquinazone
  • 1-acetyl-3,4-dihydro-3-[(3-pyridinylmethyl)amino]-6-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-2(1h)-quinazolinone
  • 1-Acetyl-1,2,3,4-tetrahydro-3-((3-pyridylmethyl)amino)-6-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)quinazolin-2-one
  • 1-acetyl-1,2,3,4-tetrahydro-3-[(3-pyridylmethyl)amino]-6-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]quinazolin-2-one
  • 1-Acetyl-3,4-dihydro-3-((3-pyridinylmethyl)amino)-6-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-2(1H)-quinazolinone
  • 1-acetyl-6-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-3-[(pyridin-3-ylmethyl)amino]-3,4-dihydroquinazolin-2(1H)-one
  • 1-acetyl-6-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-3-((pyridin-3-ylmethyl)amino)-3,4-dihydroquinazolin-2(1H)-one
  • 1,1,3,4-tetrahydro-6-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)quinazolin-2,4-dione
  • 1-Acetyl-6-(perfluoropropan-2-yl)-3-((pyridin-3-ylmethyl)amino)-3,4-dihydroquinazolin-2(1H)-one
  • 1-acetyl-6-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-3-(pyridin-3-ylmethylamino)-4H-quinazolin-2-one
  • Pyrifluquinazon 100 |Ig/mL in Acetonitrile
  • Pyrifluquinazon 100 microg/mL in Acetonitrile
  • 1-acetyl-3,4-dihydro-3-(3-pyridylmethylamino)-6-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-2(1H)-quinazolinone
  • 1-Acetyl-6-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-3-{[(pyridin-3-yl)methyl]amino}-3,4-dihydroquinazolin-2(1H)-one
  • 2(1H)-Quinazolinone, 1-acetyl-3,4-dihydro-3-[(3-pyridinylmethyl)amino]-6-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
464.34 g/molcalc.
Exact mass
464.1083 Dacalc.
LogP (octanol/water)
4.36calc.
Topological polar surface area
65.54 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
32calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.32calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1Nc2ccccc2CN1NCc1cccnc1

O=C1Nc2ccccc2CN1NCc1cccnc1

3 rings, 19 atoms.

1 other chemical share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302Harmful if swallowed.
  • H330Fatal if inhaled.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (15)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P317If swallowed: Get medical help.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Pyrifluquinazon suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 4 suppliers
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Where suppliers are based

4 suppliers in 2 countries

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Pyrifluquinazon price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pfas.

Roles

  • TRP channel modulator
  • TRPV channel modulator
  • agrochemical
  • biophysical role
  • insecticide
  • membrane transport modulator
  • pesticide

Functional uses

  • Biocide

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Pyrifluquinazon is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Pyrifluquinazon is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Pyrifluquinazon, based on the data on this page

What is Pyrifluquinazon?

Pyrifluquinazon is a member of the class of quinazolines that is 3,4-dihydroquinazolin-2-one which is substituted at positions 1, 4, and 6 by acetyl, pyridin-3-ylmethyl, and perfluoroisopropyl groups, respectively.

Is Pyrifluquinazon hazardous?

Pyrifluquinazon carries the GHS signal word "Danger". Main hazards: harmful if swallowed, fatal if inhaled, very toxic to aquatic life. This summary is not an SDS, always read the supplier safety data sheet.

Guides for buyers

Practical guides that help when you source, ship or handle Pyrifluquinazon

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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