Murcko scaffold
Ring system with 3 rings and 19 atoms
141 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 19
- Chemicals
- 141
- With full pages
- 5
Scaffold SMILES
O=S(=O)(Nc1ccccc1)c1csc2ccccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 141 chemicals
![Ethyl 3-[(4-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H17NO5S2, CAS 899965-23-2](/s/ZSFVBQGJOUMHKG-UHFFFAOYSA-N.svg)
Ethyl 3-[(4-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899965-23-2C18H17NO5S2
![Ethyl 4-fluoro-3-[(2-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H16FNO5S2, CAS 932465-05-9](/s/PRVZVNIWLGOVGH-UHFFFAOYSA-N.svg)
Ethyl 4-fluoro-3-[(2-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932465-05-9C18H16FNO5S2
![Methyl 3-[(4-ethylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C18H16FNO4S2, CAS 932303-76-9](/s/FTELJBUPRLISEC-UHFFFAOYSA-N.svg)
Methyl 3-[(4-ethylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 932303-76-9C18H16FNO4S2
![Methyl 3-[(3-ethylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C18H16FNO4S2, CAS 932464-78-3](/s/FPKWSVLOKIAVPV-UHFFFAOYSA-N.svg)
Methyl 3-[(3-ethylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 932464-78-3C18H16FNO4S2
![Methyl 3-[(2,5-dimethylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C18H16FNO4S2, CAS 932303-78-1](/s/QJVAVOKJUJKQHW-UHFFFAOYSA-N.svg)
Methyl 3-[(2,5-dimethylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 932303-78-1C18H16FNO4S2
![Methyl 3-[(4-carbamoylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C17H14N2O5S2, CAS 932520-77-9](/s/JRJLJHXEIFAZSH-UHFFFAOYSA-N.svg)
Methyl 3-[(4-carbamoylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932520-77-9C17H14N2O5S2
![Methyl 3-[(4-acetylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H15NO5S2, CAS 932304-04-6](/s/LJIJAXISYRPYCB-UHFFFAOYSA-N.svg)
Methyl 3-[(4-acetylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932304-04-6C18H15NO5S2
![Methyl 3-{[2-(methoxycarbonyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate chemical structure, C18H15NO6S2, CAS 932354-70-6](/s/MZRMUIBILXIBGN-UHFFFAOYSA-N.svg)
Methyl 3-{[2-(methoxycarbonyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate
CAS 932354-70-6C18H15NO6S2
![Methyl 3-[(2,6-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H17NO4S2, CAS 932304-06-8](/s/GMDRGQNESAYLLQ-UHFFFAOYSA-N.svg)
Methyl 3-[(2,6-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932304-06-8C18H17NO4S2
![Methyl 3-[(2-ethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H17NO4S2, CAS 932304-08-0](/s/WRAPYZBIIKXVHZ-UHFFFAOYSA-N.svg)
Methyl 3-[(2-ethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932304-08-0C18H17NO4S2
![Methyl 3-{[3-(methylsulfanyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate chemical structure, C17H15NO4S3, CAS 932465-26-4](/s/IFCXYMMELSCUDK-UHFFFAOYSA-N.svg)
Methyl 3-{[3-(methylsulfanyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate
CAS 932465-26-4C17H15NO4S3
![Methyl 3-{[(4-isopropylphenyl)amino]sulfonyl}-1-benzothiophene-2-carboxylate chemical structure, C19H19NO4S2, CAS 932354-74-0](/s/KAGZBXCAWDXEKS-UHFFFAOYSA-N.svg)
Methyl 3-{[(4-isopropylphenyl)amino]sulfonyl}-1-benzothiophene-2-carboxylate
CAS 932354-74-0C19H19NO4S2
![Ethyl 3-(N-phenylsulfamoyl)benzo[b]thiophene-2-carboxylate chemical structure, C17H15NO4S2, CAS 932464-24-9](/s/OBVAPOIQESOYPK-UHFFFAOYSA-N.svg)
Ethyl 3-(N-phenylsulfamoyl)benzo[b]thiophene-2-carboxylate
CAS 932464-24-9C17H15NO4S2
![Ethyl 3-[(4-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H17NO4S2, CAS 932303-37-2](/s/ZMZOWNJRTMUAAO-UHFFFAOYSA-N.svg)
Ethyl 3-[(4-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932303-37-2C18H17NO4S2
![Ethyl 3-[(3-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H17NO4S2, CAS 932354-06-8](/s/CVYHKGJNBIZYIA-UHFFFAOYSA-N.svg)
Ethyl 3-[(3-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932354-06-8C18H17NO4S2
![Ethyl 3-[(2-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H17NO4S2, CAS 932519-97-6](/s/QVYQSLWVTCPXPY-UHFFFAOYSA-N.svg)
Ethyl 3-[(2-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932519-97-6C18H17NO4S2
![Ethyl 3-[(3-ethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C19H19NO4S2, CAS 932464-28-3](/s/QJUIDHXFZCPXKJ-UHFFFAOYSA-N.svg)
Ethyl 3-[(3-ethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932464-28-3C19H19NO4S2
![Ethyl 3-(N-(3,4-dimethylphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate chemical structure, C19H19NO4S2, CAS 932303-39-4](/s/VHECHOMSNIOWAW-UHFFFAOYSA-N.svg)
Ethyl 3-(N-(3,4-dimethylphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate
CAS 932303-39-4C19H19NO4S2
![Ethyl 3-(N-(2,4-dimethylphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate chemical structure, C19H19NO4S2, CAS 932354-09-1](/s/PUMSLBCFTXKUEU-UHFFFAOYSA-N.svg)
Ethyl 3-(N-(2,4-dimethylphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate
CAS 932354-09-1C19H19NO4S2
![Ethyl 3-[(2,5-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C19H19NO4S2, CAS 932520-00-8](/s/HCLJZSIUHHDOHU-UHFFFAOYSA-N.svg)
Ethyl 3-[(2,5-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932520-00-8C19H19NO4S2
![Ethyl 3-[(3,5-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C19H19NO4S2, CAS 932464-32-9](/s/QJFNKZPQCVWUMC-UHFFFAOYSA-N.svg)
Ethyl 3-[(3,5-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932464-32-9C19H19NO4S2
![Ethyl 3-[(2,3-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C19H19NO4S2, CAS 932464-37-4](/s/BGQNCTBZEMWNKU-UHFFFAOYSA-N.svg)
Ethyl 3-[(2,3-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932464-37-4C19H19NO4S2
![Ethyl 3-[(2-methoxy-5-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C19H19NO5S2, CAS 932303-43-0](/s/IWENOKFKLYLPPF-UHFFFAOYSA-N.svg)
Ethyl 3-[(2-methoxy-5-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932303-43-0C19H19NO5S2
![Methyl 4-fluoro-3-(N-(m-tolyl)sulfamoyl)benzo[b]thiophene-2-carboxylate chemical structure, C17H14FNO4S2, CAS 932354-33-1](/s/UVPSXYCZGYKQJB-UHFFFAOYSA-N.svg)
Methyl 4-fluoro-3-(N-(m-tolyl)sulfamoyl)benzo[b]thiophene-2-carboxylate
CAS 932354-33-1C17H14FNO4S2
- Methyl 3-[(3,5-dimethylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate932464-81-8C18H16FNO4S2
- Methyl 4-fluoro-3-[(2-methoxy-5-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932303-80-5C18H16FNO5S2
- Methyl 3-[(4-methoxycarbonylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932465-23-1C18H15NO6S2
- Methyl 3-[(2,4,6-trimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932465-29-7C19H19NO4S2
- Methyl 4-fluoro-3-[(2-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932520-38-2C17H14FNO4S2
- Methyl 3-[(3,4-dimethylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate932354-35-3C18H16FNO4S2
- Methyl 3-(N-(2,4-dimethylphenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate932520-41-7C18H16FNO4S2
- Methyl 3-[(4-chlorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932354-66-0C16H12ClNO4S2
- Methyl 3-[(3-chlorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932520-80-4C16H12ClNO4S2
- Ethyl 3-[(3-chloro-4-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932303-41-8C18H16ClNO4S2
- Ethyl 3-(N-(3-fluoro-4-methylphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate932354-11-5C18H16FNO4S2
- Ethyl 3-[(2-chloro-4-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932520-03-1C18H16ClNO4S2
- Ethyl 3-[(3-chloro-2-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932520-07-5C18H16ClNO4S2
- Ethyl 3-[(5-fluoro-2-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932464-42-1C18H16FNO4S2
- Ethyl 3-(N-(5-chloro-2-methylphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate932303-46-3C18H16ClNO4S2
- Ethyl 3-[(4-fluorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932520-11-1C17H14FNO4S2
- Ethyl 3-[(2,4-difluorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932464-47-6C17H13F2NO4S2
- Ethyl 3-[(3,4-difluorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932303-49-6C17H13F2NO4S2
- Ethyl 3-[(3-fluorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932354-17-1C17H14FNO4S2
- Ethyl 3-[(2,5-difluorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932520-14-4C17H13F2NO4S2
- Ethyl 3-[(2-fluorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932464-52-3C17H14FNO4S2
- Methyl 4-fluoro-3-[(4-fluorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932354-40-0C16H11F2NO4S2
- Methyl 3-[(4-fluoro-2-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932354-76-2C17H14FNO4S2
- Ethyl 3-(N-(3-chloro-4-methoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate932464-56-7C18H16ClNO5S2
Related scaffolds
Same ring framework with different atoms or bond orders
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