Murcko scaffold
Ring system with 3 rings and 19 atoms
141 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 19
- Chemicals
- 141
- With full pages
- 5
Scaffold SMILES
O=S(=O)(Nc1ccccc1)c1csc2ccccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 97 to 141 of 141 chemicals
![Ethyl 3-[(4-ethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C19H18FNO5S2, CAS 899972-21-5](/s/GTMYAMWVISZXJE-UHFFFAOYSA-N.svg)
Ethyl 3-[(4-ethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 899972-21-5C19H18FNO5S2
![Ethyl 3-[(3,4-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C19H18FNO6S2, CAS 899724-40-4](/s/MRQJBBVDHFEAHJ-UHFFFAOYSA-N.svg)
Ethyl 3-[(3,4-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 899724-40-4C19H18FNO6S2
![Ethyl 3-[(2,4-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C19H18FNO6S2, CAS 900013-10-7](/s/MMNCHJLHMRYOTJ-UHFFFAOYSA-N.svg)
Ethyl 3-[(2,4-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 900013-10-7C19H18FNO6S2
![Ethyl 3-[(3-chloro-4-methoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C18H15ClFNO5S2, CAS 899972-23-7](/s/MVCAGNKJSURSEC-UHFFFAOYSA-N.svg)
Ethyl 3-[(3-chloro-4-methoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 899972-23-7C18H15ClFNO5S2
![Ethyl 4-fluoro-3-[(3,4,5-trimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C20H20FNO7S2, CAS 899724-42-6](/s/DTOWXTVVMFORNE-UHFFFAOYSA-N.svg)
Ethyl 4-fluoro-3-[(3,4,5-trimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899724-42-6C20H20FNO7S2
![Ethyl 3-[(5-chloro-2,4-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C19H17ClFNO6S2, CAS 899724-44-8](/s/SFBOPHBUVFOCNF-UHFFFAOYSA-N.svg)
Ethyl 3-[(5-chloro-2,4-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 899724-44-8C19H17ClFNO6S2
![Ethyl 3-[(2,5-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C19H18FNO6S2, CAS 932465-02-6](/s/MIFFDJYNDWZVGJ-UHFFFAOYSA-N.svg)
Ethyl 3-[(2,5-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 932465-02-6C19H18FNO6S2
![Ethyl 3-[(3,5-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C19H18FNO6S2, CAS 932520-65-5](/s/TZMWTVHGYFQVLH-UHFFFAOYSA-N.svg)
Ethyl 3-[(3,5-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 932520-65-5C19H18FNO6S2
![Ethyl 3-[(5-chloro-2-methoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C18H15ClFNO5S2, CAS 932303-94-1](/s/SILZXTWEMRUIKW-UHFFFAOYSA-N.svg)
Ethyl 3-[(5-chloro-2-methoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 932303-94-1C18H15ClFNO5S2
![Ethyl 3-[(2-ethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C19H18FNO5S2, CAS 932354-60-4](/s/XWCIDPCKDGUNGG-UHFFFAOYSA-N.svg)
Ethyl 3-[(2-ethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 932354-60-4C19H18FNO5S2
![Methyl 3-[(3-chloro-4-fluorophenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C16H10ClF2NO4S2, CAS 932464-84-1](/s/IYGZXHNHLFMVQL-UHFFFAOYSA-N.svg)
Methyl 3-[(3-chloro-4-fluorophenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 932464-84-1C16H10ClF2NO4S2
![Methyl 3-(N-(2,4-dimethoxyphenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate chemical structure, C18H16FNO6S2, CAS 932354-43-3](/s/NXPPRCVGIYGKIZ-UHFFFAOYSA-N.svg)
Methyl 3-(N-(2,4-dimethoxyphenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate
CAS 932354-43-3C18H16FNO6S2
![Methyl 3-[(5-chloro-2,4-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C18H15ClFNO6S2, CAS 932303-86-1](/s/DHTIGEAOACUYFB-UHFFFAOYSA-N.svg)
Methyl 3-[(5-chloro-2,4-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 932303-86-1C18H15ClFNO6S2
![Methyl 3-{[3-(trifluoromethyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate chemical structure, C17H12F3NO4S2, CAS 932304-02-4](/s/GYNVDKXYQCVPCD-UHFFFAOYSA-N.svg)
Methyl 3-{[3-(trifluoromethyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate
CAS 932304-02-4C17H12F3NO4S2
![Methyl 3-{[4-(ethoxycarbonyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate chemical structure, C19H17NO6S2, CAS 932465-17-3](/s/PUDYQSTWEQNPPV-UHFFFAOYSA-N.svg)
Methyl 3-{[4-(ethoxycarbonyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate
CAS 932465-17-3C19H17NO6S2
![Methyl 3-[(4-bromo-3-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C17H14BrNO4S2, CAS 932354-68-2](/s/ORSANMBBWPYIKQ-UHFFFAOYSA-N.svg)
Methyl 3-[(4-bromo-3-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932354-68-2C17H14BrNO4S2
![Methyl 3-[(4-bromophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C16H12BrNO4S2, CAS 932520-83-7](/s/WAPZALWNARVCKX-UHFFFAOYSA-N.svg)
Methyl 3-[(4-bromophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932520-83-7C16H12BrNO4S2
![Ethyl 3-(N-(3-chloro-4-fluorophenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate chemical structure, C17H13ClFNO4S2, CAS 932354-15-9](/s/AUCPIZUGOJOTES-UHFFFAOYSA-N.svg)
Ethyl 3-(N-(3-chloro-4-fluorophenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate
CAS 932354-15-9C17H13ClFNO4S2
![Methyl 3-(N-(3-chloro-4-methylphenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate chemical structure, C17H13ClFNO4S2, CAS 932354-37-5](/s/HAQVWPKSRRDXER-UHFFFAOYSA-N.svg)
Methyl 3-(N-(3-chloro-4-methylphenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate
CAS 932354-37-5C17H13ClFNO4S2
![Methyl 3-{[3-(ethoxycarbonyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate chemical structure, C19H17NO6S2, CAS 932520-89-3](/s/DNSIWTJLRCVTAS-UHFFFAOYSA-N.svg)
Methyl 3-{[3-(ethoxycarbonyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate
CAS 932520-89-3C19H17NO6S2
![Ethyl 3-[(4-chloro-2-methoxy-5-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C19H18ClNO5S2, CAS 932354-13-7](/s/DZHJGSURGGKKKB-UHFFFAOYSA-N.svg)
Ethyl 3-[(4-chloro-2-methoxy-5-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932354-13-7C19H18ClNO5S2
![Ethyl 3-(N-(4-ethoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate chemical structure, C19H19NO5S2, CAS 932303-52-1](/s/OXECUYXJQJYKKN-UHFFFAOYSA-N.svg)
Ethyl 3-(N-(4-ethoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate
CAS 932303-52-1C19H19NO5S2
![Ethyl 3-(N-(2,4-dimethoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate chemical structure, C19H19NO6S2, CAS 932520-17-7](/s/BUGDRIBDGNQPDK-UHFFFAOYSA-N.svg)
Ethyl 3-(N-(2,4-dimethoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate
CAS 932520-17-7C19H19NO6S2
![Ethyl 3-[(3,4,5-trimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C20H21NO7S2, CAS 932354-21-7](/s/FHNPTCCULKPYLX-UHFFFAOYSA-N.svg)
Ethyl 3-[(3,4,5-trimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932354-21-7C20H21NO7S2
- Ethyl 3-(N-(5-chloro-2,4-dimethoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate932464-60-3C19H18ClNO6S2
- Ethyl 3-[(3-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932303-58-7C18H17NO5S2
- Ethyl 3-[(3,5-dimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932354-23-9C19H19NO6S2
- Ethyl 3-[(5-chloro-2-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932520-23-5C18H16ClNO5S2
- Ethyl 3-(N-(2-methoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate932464-63-6C18H17NO5S2
- Ethyl 3-(N-(2-ethoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate932303-61-2C19H19NO5S2
- Methyl 3-[(3,4-difluorophenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate941893-01-2C16H10F3NO4S2
- Methyl 3-[(4-ethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate932303-82-7C18H16FNO5S2
- Methyl 4-fluoro-3-[(2-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate941893-03-4C17H14FNO5S2
- Ethyl 3-[(4-chlorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932520-92-8C17H14ClNO4S2
- Ethyl 3-[(3-chlorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932354-78-4C17H14ClNO4S2
- Ethyl 3-[(2-chlorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932304-14-8C17H14ClNO4S2
- Ethyl 3-{[2-(methoxycarbonyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate932354-80-8C19H17NO6S2
- Ethyl 3-[(4-bromophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932520-98-4C17H14BrNO4S2
- Ethyl 3-{[4-(methoxycarbonyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate932465-39-9C19H17NO6S2
- Methyl 3-[(5-chloro-2-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate932353-97-4C17H14ClNO5S2
- Methyl 3-[(2,4-difluorophenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate950446-11-4C16H10F3NO4S2
- Methyl 3-[(5-chloro-2-methoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate951572-28-4C17H13ClFNO5S2
- Methyl 3-[(2,5-diethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate946300-77-2C20H21NO6S2
- Ethyl 3-{[4-(trifluoromethoxy)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate932303-55-4C18H14F3NO5S2
- Methyl 3-[(2-cyano-3-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate1955506-63-4C18H14N2O4S2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(CC1C(=O)Nc2ccccc21)c1ccccc163 chemicals
c1ccc(CCn2cnc3ccccc32)cc122 chemicals
c1ccc(NCn2nnc3ccccc32)cc122 chemicals![Scaffold O=c1[nH]c(=O)c2c(ncn2CCc2ccccc2)[nH]1](/scaffold/JFWWZQRBIJRXQC-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(ncn2CCc2ccccc2)[nH]121 chemicals![Scaffold c1ccc(N=Nc2c[nH]c3ccccc23)cc1](/scaffold/CHWPRPBKMKFUPJ-UHFFFAOYSA-N/structure.svg)
c1ccc(N=Nc2c[nH]c3ccccc23)cc120 chemicals
O=C(Cn1cnc2ccccc21)c1ccccc116 chemicals
O=C(Nc1ccccc1)c1csc2c1CCCC215 chemicals![Scaffold O=C(Cc1ccccc1)c1c[nH]c2ccccc12](/scaffold/MVJGJYRFWKGPTI-UHFFFAOYSA-N/structure.svg)
O=C(Cc1ccccc1)c1c[nH]c2ccccc1212 chemicals![Scaffold O=C(CN1CCCCC1)c1c[nH]c2ccccc12](/scaffold/CDRQAUBCVZVLOJ-UHFFFAOYSA-N/structure.svg)
O=C(CN1CCCCC1)c1c[nH]c2ccccc1211 chemicals![Scaffold O=c1nc[nH]c2[nH]cc(CCc3ccccc3)c12](/scaffold/GYMUFHDRARXLAZ-UHFFFAOYSA-N/structure.svg)
O=c1nc[nH]c2[nH]cc(CCc3ccccc3)c1211 chemicals
O=C(CC1OC(=O)c2ccccc21)c1ccccc111 chemicals![Scaffold O=C(Nc1ccccc1)c1c[nH]c2ccccc12](/scaffold/ARNKSDBIZXVFHP-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1c[nH]c2ccccc129 chemicals