Murcko scaffold
Ring system with 3 rings and 19 atoms
141 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 19
- Chemicals
- 141
- With full pages
- 5
Scaffold SMILES
O=S(=O)(Nc1ccccc1)c1csc2ccccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 141 chemicals
![Ethyl 3-(N-(2,5-dimethoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate chemical structure, C19H19NO6S2, CAS 941892-95-1](/s/NRTCKPXROJNHJV-UHFFFAOYSA-N.svg)
Ethyl 3-(N-(2,5-dimethoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate
CAS 941892-95-1C19H19NO6S2
![Ethyl 3-(N-(4-(dimethylamino)phenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate chemical structure, C19H20N2O4S2, CAS 932354-25-1](/s/HZCMVMNNPBYDCM-UHFFFAOYSA-N.svg)
Ethyl 3-(N-(4-(dimethylamino)phenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate
CAS 932354-25-1C19H20N2O4S2
![Methyl 3-(N-(2-chloro-4-methylphenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate chemical structure, C17H13ClFNO4S2, CAS 941919-15-9](/s/LHYVPUQSWDACFN-UHFFFAOYSA-N.svg)
Methyl 3-(N-(2-chloro-4-methylphenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate
CAS 941919-15-9C17H13ClFNO4S2
![Methyl 3-[(4-chloro-2-methoxy-5-methylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C18H15ClFNO5S2, CAS 941962-27-2](/s/UNVFFCGRUKQOJA-UHFFFAOYSA-N.svg)
Methyl 3-[(4-chloro-2-methoxy-5-methylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 941962-27-2C18H15ClFNO5S2
![Methyl 3-[(3,5-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C18H16FNO6S2, CAS 941962-29-4](/s/YQVGDNJCZXASNI-UHFFFAOYSA-N.svg)
Methyl 3-[(3,5-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 941962-29-4C18H16FNO6S2
![Methyl 3-[(2-ethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C18H16FNO5S2, CAS 941919-21-7](/s/MMXQSJITXXINOE-UHFFFAOYSA-N.svg)
Methyl 3-[(2-ethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate
CAS 941919-21-7C18H16FNO5S2
![Methyl 3-{[4-(dimethylamino)phenyl]sulfamoyl}-4-fluoro-1-benzothiophene-2-carboxylate chemical structure, C18H17FN2O4S2, CAS 941962-31-8](/s/VWFZNDAFBUMLTE-UHFFFAOYSA-N.svg)
Methyl 3-{[4-(dimethylamino)phenyl]sulfamoyl}-4-fluoro-1-benzothiophene-2-carboxylate
CAS 941962-31-8C18H17FN2O4S2
![Ethyl 3-{[3-(trifluoromethyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate chemical structure, C18H14F3NO4S2, CAS 932465-32-2](/s/JFGFUPJONIKORY-UHFFFAOYSA-N.svg)
Ethyl 3-{[3-(trifluoromethyl)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate
CAS 932465-32-2C18H14F3NO4S2
![Ethyl 3-[(4-acetylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C19H17NO5S2, CAS 932465-35-5](/s/PLYFGFKKEJPWCM-UHFFFAOYSA-N.svg)
Ethyl 3-[(4-acetylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932465-35-5C19H17NO5S2
![Ethyl 3-[(2,6-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C19H19NO4S2, CAS 932304-16-0](/s/VCNKKPQWHQFBBO-UHFFFAOYSA-N.svg)
Ethyl 3-[(2,6-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932304-16-0C19H19NO4S2
Methyl 3-(phenylsulfamoyl)-1-benzothiophene-2-carboxylate
CAS 899965-94-7C16H13NO4S2
![Methyl 3-[(4-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C17H15NO4S2, CAS 899977-35-6](/s/MFVIVPBLIIGGKE-UHFFFAOYSA-N.svg)
Methyl 3-[(4-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899977-35-6C17H15NO4S2
![Methyl 3-[(2-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C17H15NO4S2, CAS 899965-95-8](/s/MWLXFEWWVHCZPO-UHFFFAOYSA-N.svg)
Methyl 3-[(2-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899965-95-8C17H15NO4S2
![Methyl 3-[(3,4-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H17NO4S2, CAS 899725-16-7](/s/QCPGIAAUOLBNMP-UHFFFAOYSA-N.svg)
Methyl 3-[(3,4-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899725-16-7C18H17NO4S2
![Methyl 3-[(2,4-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H17NO4S2, CAS 899965-96-9](/s/JUJCNFLVRHWAQY-UHFFFAOYSA-N.svg)
Methyl 3-[(2,4-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899965-96-9C18H17NO4S2
![Methyl 3-[(2,5-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H17NO4S2, CAS 899977-39-0](/s/XDKFSTPNTROZJN-UHFFFAOYSA-N.svg)
Methyl 3-[(2,5-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899977-39-0C18H17NO4S2
![Methyl 3-[(3,5-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H17NO4S2, CAS 899725-18-9](/s/FLIBGRCEFVEQNE-UHFFFAOYSA-N.svg)
Methyl 3-[(3,5-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899725-18-9C18H17NO4S2
![Methyl 3-[(2,3-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H17NO4S2, CAS 899965-99-2](/s/KFHKGSJIPOBWMP-UHFFFAOYSA-N.svg)
Methyl 3-[(2,3-dimethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899965-99-2C18H17NO4S2
![Methyl 3-[(4-chloro-2-methoxy-5-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H16ClNO5S2, CAS 899725-22-5](/s/ILCKFMUPJUTLNX-UHFFFAOYSA-N.svg)
Methyl 3-[(4-chloro-2-methoxy-5-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899725-22-5C18H16ClNO5S2
![Methyl 3-[(3-chloro-4-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C17H14ClNO5S2, CAS 899977-51-6](/s/IWNXJUJVIGIWBV-UHFFFAOYSA-N.svg)
Methyl 3-[(3-chloro-4-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899977-51-6C17H14ClNO5S2
![Methyl 3-[(5-chloro-2,4-dimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C18H16ClNO6S2, CAS 899725-76-9](/s/MPRNUIPFMPFQQJ-UHFFFAOYSA-N.svg)
Methyl 3-[(5-chloro-2,4-dimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 899725-76-9C18H16ClNO6S2
![Methyl 3-(N-(3,4-dimethoxyphenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate chemical structure, C18H16FNO6S2, CAS 932464-87-4](/s/SZDZVBAUQZAELV-UHFFFAOYSA-N.svg)
Methyl 3-(N-(3,4-dimethoxyphenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate
CAS 932464-87-4C18H16FNO6S2
![Methyl 3-(N-(3-chloro-4-methoxyphenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate chemical structure, C17H13ClFNO5S2, CAS 932520-50-8](/s/NXTUUVIZUDTJDO-UHFFFAOYSA-N.svg)
Methyl 3-(N-(3-chloro-4-methoxyphenyl)sulfamoyl)-4-fluorobenzo[b]thiophene-2-carboxylate
CAS 932520-50-8C17H13ClFNO5S2
![Methyl 4-fluoro-3-[(3,4,5-trimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate chemical structure, C19H18FNO7S2, CAS 932464-90-9](/s/GZKNWKLFXWAJSS-UHFFFAOYSA-N.svg)
Methyl 4-fluoro-3-[(3,4,5-trimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate
CAS 932464-90-9C19H18FNO7S2
- Methyl 3-[(2,5-dimethoxyphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate932464-93-2C18H16FNO6S2
- Ethyl 3-(N-(3,4-dimethoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate932354-19-3C19H19NO6S2
- Methyl 4-fluoro-3-[(3-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate941919-18-2C17H14FNO5S2
- Methyl 3-[(4-ethylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899977-37-8C18H17NO4S2
- Methyl 3-[(3-chloro-4-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899965-97-0C17H14ClNO4S2
- Methyl 3-[(3-fluoro-4-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899977-41-4C17H14FNO4S2
- Methyl 3-[(5-chloro-2-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899725-24-7C17H14ClNO4S2
- Methyl 3-[(3,4-difluorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899725-26-9C16H11F2NO4S2
- Methyl 3-[(4-ethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899977-49-2C18H17NO5S2
- Methyl 3-[(3,4-dimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899725-28-1C18H17NO6S2
- Methyl 3-[(2,4-dimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899966-06-4C18H17NO6S2
- Methyl 3-{[4-(trifluoromethoxy)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate899725-30-5C17H12F3NO5S2
- Methyl 3-[(4-methoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899966-07-5C17H15NO5S2
- Methyl 3-[(3,4,5-trimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899977-53-8C19H19NO7S2
- Methyl 3-[(3,5-dimethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899978-05-3C18H17NO6S2
- Methyl 3-[(2-ethoxyphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899978-08-6C18H17NO5S2
- Methyl 3-{[4-(dimethylamino)phenyl]sulfamoyl}-1-benzothiophene-2-carboxylate899949-66-7C18H18N2O4S2
- Ethyl 4-fluoro-3-[(3-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate900012-69-3C18H16FNO4S2
- Ethyl 3-[(3-ethylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate899971-40-5C19H18FNO4S2
- Ethyl 3-[(2,5-dimethylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate900012-70-6C19H18FNO4S2
- Ethyl 3-[(3,5-dimethylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate899971-42-7C19H18FNO4S2
- Ethyl 4-fluoro-3-[(2-methoxy-5-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate900013-08-3C19H18FNO5S2
- Ethyl 3-[(4-chloro-2-methoxy-5-methylphenyl)sulfamoyl]-4-fluoro-1-benzothiophene-2-carboxylate899972-19-1C19H17ClFNO5S2
- Ethyl 4-fluoro-3-[(4-fluorophenyl)sulfamoyl]-1-benzothiophene-2-carboxylate899724-38-0C17H13F2NO4S2
Related scaffolds
Same ring framework with different atoms or bond orders
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c1ccc(N=Nc2c[nH]c3ccccc23)cc120 chemicals
O=C(Cn1cnc2ccccc21)c1ccccc116 chemicals
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O=C(Nc1ccccc1)c1c[nH]c2ccccc129 chemicals