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Murcko scaffold

Ring system with 3 rings and 20 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
10
With full pages
2
Scaffold SMILES

O=C1CCCC(c2ccccc2)N1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCC(c2ccccc2)N1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1-[(4-Methoxyphenyl)methyl]-6-oxo-2-phenylpiperidine-3-carboxylic acid chemical structure, C20H21NO4, CAS 439110-93-7
1-[(4-Methoxyphenyl)methyl]-6-oxo-2-phenylpiperidine-3-carboxylic acid
CAS 439110-93-7C20H21NO4
Olnfxrmjxpojak-sjorkvtesa- chemical structure, C18H17ClFNO, CAS 149437-78-5
Olnfxrmjxpojak-sjorkvtesa-
CAS 149437-78-5C18H17ClFNO
1-Benzyl-6-hydroxy-3-methyl-6-phenylpiperidin-2-one chemical structure, C19H21NO2, CAS 65094-60-2
1-Benzyl-6-hydroxy-3-methyl-6-phenylpiperidin-2-one
CAS 65094-60-2C19H21NO2
1-Benzyl-6-oxo-2-phenylpiperidine-3-carboxylic acid chemical structure, C19H19NO3, CAS 94655-32-0
1-Benzyl-6-oxo-2-phenylpiperidine-3-carboxylic acid
CAS 94655-32-0C19H19NO3
1-Benzyl-5-(hydroxymethyl)-6-(4-methoxyphenyl)piperidin-2-one chemical structure, C20H23NO3, CAS 937604-02-9
1-Benzyl-5-(hydroxymethyl)-6-(4-methoxyphenyl)piperidin-2-one
CAS 937604-02-9C20H23NO3
1-Benzyl-2-(4-isopropylphenyl)-6-oxo-3-piperidinecarboxylic acid chemical structure, C22H25NO3, CAS 937604-04-1
1-Benzyl-2-(4-isopropylphenyl)-6-oxo-3-piperidinecarboxylic acid
CAS 937604-04-1C22H25NO3
1-Benzyl-2-(4-methoxyphenyl)-6-oxopiperidine-3-carboxylic acid chemical structure, C20H21NO4, CAS 937604-06-3
1-Benzyl-2-(4-methoxyphenyl)-6-oxopiperidine-3-carboxylic acid
CAS 937604-06-3C20H21NO4
1-Benzyl-2-[4-(tert-butyl)phenyl]-6-oxo-3-piperidinecarboxylic acid chemical structure, C23H27NO3, CAS 952182-64-8
1-Benzyl-2-[4-(tert-butyl)phenyl]-6-oxo-3-piperidinecarboxylic acid
CAS 952182-64-8C23H27NO3
3-Piperidinecarboxylic acid, 2-(4-methoxyphenyl)-6-oxo-1-(phenylmethyl)-, (2R,3R)-rel- chemical structure, C20H21NO4, CAS 1943733-57-0
3-Piperidinecarboxylic acid, 2-(4-methoxyphenyl)-6-oxo-1-(phenylmethyl)-, (2R,3R)-rel-
CAS 1943733-57-0C20H21NO4
1-(4-Chlorobenzyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one chemical structure, C20H22ClNO3, CAS 1375094-53-3
1-(4-Chlorobenzyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one
CAS 1375094-53-3C20H22ClNO3