CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
14
With full pages
7
Scaffold SMILES

O=S(=O)(c1ccccc1)c1cncnc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)c1cncnc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

4-(4-Chlorophenyl)-5-[(4-chlorophenyl)sulfonyl]-2-pyrimidinamine chemical structure, C16H11Cl2N3O2S, CAS 338417-69-9
4-(4-Chlorophenyl)-5-[(4-chlorophenyl)sulfonyl]-2-pyrimidinamine
CAS 338417-69-9C16H11Cl2N3O2S
4-(4-Chlorophenyl)-5-[(4-methylphenyl)sulfonyl]-2-pyrimidinamine chemical structure, C17H14ClN3O2S, CAS 338417-79-1
4-(4-Chlorophenyl)-5-[(4-methylphenyl)sulfonyl]-2-pyrimidinamine
CAS 338417-79-1C17H14ClN3O2S
5-(Benzenesulfonyl)-4-(4-chlorophenyl)-N,N-dimethylpyrimidin-2-amine chemical structure, C18H16ClN3O2S, CAS 339097-54-0
5-(Benzenesulfonyl)-4-(4-chlorophenyl)-N,N-dimethylpyrimidin-2-amine
CAS 339097-54-0C18H16ClN3O2S
N-[4-(2-Chlorophenyl)-5-(phenylsulfonyl)-2-pyrimidinyl]-N,N-dimethylamine chemical structure, C18H16ClN3O2S, CAS 339107-53-8
N-[4-(2-Chlorophenyl)-5-(phenylsulfonyl)-2-pyrimidinyl]-N,N-dimethylamine
CAS 339107-53-8C18H16ClN3O2S
5-(Benzenesulfonyl)-4-(3,4-dichlorophenyl)-N,N-dimethylpyrimidin-2-amine chemical structure, C18H15Cl2N3O2S, CAS 339107-76-5
5-(Benzenesulfonyl)-4-(3,4-dichlorophenyl)-N,N-dimethylpyrimidin-2-amine
CAS 339107-76-5C18H15Cl2N3O2S
5-(Benzenesulfonyl)-N,N-dimethyl-4-phenylpyrimidin-2-amine chemical structure, C18H17N3O2S, CAS 339107-78-7
5-(Benzenesulfonyl)-N,N-dimethyl-4-phenylpyrimidin-2-amine
CAS 339107-78-7C18H17N3O2S
5-(Benzenesulfonyl)-4-(2,4-dichlorophenyl)-N,N-dimethylpyrimidin-2-amine chemical structure, C18H15Cl2N3O2S, CAS 339107-80-1
5-(Benzenesulfonyl)-4-(2,4-dichlorophenyl)-N,N-dimethylpyrimidin-2-amine
CAS 339107-80-1C18H15Cl2N3O2S
5-(Benzenesulfonyl)-4-(2,4-dichlorophenyl)-2-methylpyrimidine chemical structure, C17H12Cl2N2O2S, CAS 339107-88-9
5-(Benzenesulfonyl)-4-(2,4-dichlorophenyl)-2-methylpyrimidine
CAS 339107-88-9C17H12Cl2N2O2S
5-(Benzenesulfonyl)-2-methyl-4-phenylpyrimidine chemical structure, C17H14N2O2S, CAS 339107-90-3
5-(Benzenesulfonyl)-2-methyl-4-phenylpyrimidine
CAS 339107-90-3C17H14N2O2S
N-{5-[(4-Chlorophenyl)sulfonyl]-4-phenyl-2-pyrimidinyl}-N,N-dimethylamine chemical structure, C18H16ClN3O2S, CAS 339108-34-8
N-{5-[(4-Chlorophenyl)sulfonyl]-4-phenyl-2-pyrimidinyl}-N,N-dimethylamine
CAS 339108-34-8C18H16ClN3O2S
4-Chlorophenyl 2-methyl-4-phenyl-5-pyrimidinyl sulfone chemical structure, C17H13ClN2O2S, CAS 339108-35-9
4-Chlorophenyl 2-methyl-4-phenyl-5-pyrimidinyl sulfone
CAS 339108-35-9C17H13ClN2O2S
5-(Benzenesulfonyl)-4-(2-chlorophenyl)-2-methylpyrimidine chemical structure, C17H13ClN2O2S, CAS 400089-29-4
5-(Benzenesulfonyl)-4-(2-chlorophenyl)-2-methylpyrimidine
CAS 400089-29-4C17H13ClN2O2S
N-[5-[(4-Chlorophenyl)sulfonyl]-4-(2,4-dichlorophenyl)-2-pyrimidinyl]-N,N-dimethylamine chemical structure, C18H14Cl3N3O2S, CAS 339110-24-6
N-[5-[(4-Chlorophenyl)sulfonyl]-4-(2,4-dichlorophenyl)-2-pyrimidinyl]-N,N-dimethylamine
CAS 339110-24-6C18H14Cl3N3O2S
4-Chlorophenyl 4-(2,4-dichlorophenyl)-2-methyl-5-pyrimidinyl sulfone chemical structure, C17H11Cl3N2O2S, CAS 400089-30-7
4-Chlorophenyl 4-(2,4-dichlorophenyl)-2-methyl-5-pyrimidinyl sulfone
CAS 400089-30-7C17H11Cl3N2O2S