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Murcko scaffold

Ring system with 3 rings and 20 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
17
With full pages
7
Scaffold SMILES

O=C1CC(NCc2ccco2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(NCc2ccco2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

1-(4-Bromophenyl)-3-[(2-furylmethyl)amino]-2,5-pyrrolidinedione chemical structure, C15H13BrN2O3, CAS 299408-24-5
1-(4-Bromophenyl)-3-[(2-furylmethyl)amino]-2,5-pyrrolidinedione
CAS 299408-24-5C15H13BrN2O3
3-(Furan-2-ylmethylamino)-1-(4-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C16H16N2O4, CAS 299408-36-9
3-(Furan-2-ylmethylamino)-1-(4-methoxyphenyl)pyrrolidine-2,5-dione
CAS 299408-36-9C16H16N2O4
1-(4-Fluorophenyl)-3-(furan-2-ylmethylamino)pyrrolidine-2,5-dione chemical structure, C15H13FN2O3, CAS 330548-44-2
1-(4-Fluorophenyl)-3-(furan-2-ylmethylamino)pyrrolidine-2,5-dione
CAS 330548-44-2C15H13FN2O3
1-(4-Ethoxyphenyl)-3-(furan-2-ylmethylamino)pyrrolidine-2,5-dione chemical structure, C17H18N2O4, CAS 466684-23-1
1-(4-Ethoxyphenyl)-3-(furan-2-ylmethylamino)pyrrolidine-2,5-dione
CAS 466684-23-1C17H18N2O4
3-(Furan-2-ylmethylamino)-1-(4-propoxyphenyl)pyrrolidine-2,5-dione chemical structure, C18H20N2O4, CAS 329716-87-2
3-(Furan-2-ylmethylamino)-1-(4-propoxyphenyl)pyrrolidine-2,5-dione
CAS 329716-87-2C18H20N2O4
4-[(2,5-Dioxo-1-phenylpyrrolidin-3-yl)(furan-2-ylmethyl)amino]-4-oxobutanoic acid chemical structure, C19H18N2O6, CAS 470694-87-2
4-[(2,5-Dioxo-1-phenylpyrrolidin-3-yl)(furan-2-ylmethyl)amino]-4-oxobutanoic acid
CAS 470694-87-2C19H18N2O6
Methyl 4-[3-(furan-2-ylmethylamino)-2,5-dioxopyrrolidin-1-yl]benzoate chemical structure, C17H16N2O5, CAS 355141-24-1
Methyl 4-[3-(furan-2-ylmethylamino)-2,5-dioxopyrrolidin-1-yl]benzoate
CAS 355141-24-1C17H16N2O5
N-[1-(4-Bromophenyl)-2,5-dioxopyrrolidin-3-yl]-N-(furan-2-ylmethyl)propanamide chemical structure, C18H17BrN2O4, CAS 470695-15-9
N-[1-(4-Bromophenyl)-2,5-dioxopyrrolidin-3-yl]-N-(furan-2-ylmethyl)propanamide
CAS 470695-15-9C18H17BrN2O4
N-[1-(4-Bromophenyl)-2,5-dioxopyrrolidin-3-yl]-N-(furan-2-ylmethyl)acetamide chemical structure, C17H15BrN2O4, CAS 340696-85-7
N-[1-(4-Bromophenyl)-2,5-dioxopyrrolidin-3-yl]-N-(furan-2-ylmethyl)acetamide
CAS 340696-85-7C17H15BrN2O4
N-(2,5-Dioxo-1-phenylpyrrolidin-3-yl)-N-(furan-2-ylmethyl)propanamide chemical structure, C18H18N2O4, CAS 339988-77-1
N-(2,5-Dioxo-1-phenylpyrrolidin-3-yl)-N-(furan-2-ylmethyl)propanamide
CAS 339988-77-1C18H18N2O4
4-{[2,5-Dioxo-1-(4-propoxyphenyl)pyrrolidin-3-yl](furan-2-ylmethyl)amino}-4-oxobutanoic acid chemical structure, C22H24N2O7, CAS 470695-83-1
4-{[2,5-Dioxo-1-(4-propoxyphenyl)pyrrolidin-3-yl](furan-2-ylmethyl)amino}-4-oxobutanoic acid
CAS 470695-83-1C22H24N2O7
Methyl 4-{3-[(furan-2-ylmethyl)(methylcarbamothioyl)amino]-2,5-dioxopyrrolidin-1-yl}benzoate chemical structure, C19H19N3O5S, CAS 471261-28-6
Methyl 4-{3-[(furan-2-ylmethyl)(methylcarbamothioyl)amino]-2,5-dioxopyrrolidin-1-yl}benzoate
CAS 471261-28-6C19H19N3O5S
3-[(Furan-2-ylmethyl)amino]-1-(4-iodophenyl)pyrrolidine-2,5-dione chemical structure, C15H13IN2O3, CAS 340696-64-2
3-[(Furan-2-ylmethyl)amino]-1-(4-iodophenyl)pyrrolidine-2,5-dione
CAS 340696-64-2C15H13IN2O3
1-(4-Chlorophenyl)-3-[(furan-2-ylmethyl)amino]pyrrolidine-2,5-dione chemical structure, C15H13ClN2O3, CAS 299408-40-5
1-(4-Chlorophenyl)-3-[(furan-2-ylmethyl)amino]pyrrolidine-2,5-dione
CAS 299408-40-5C15H13ClN2O3
N-[1-(4-Chlorophenyl)-2,5-dioxopyrrolidin-3-yl]-N-(furan-2-ylmethyl)acetamide chemical structure, C17H15ClN2O4, CAS 1008865-59-5
N-[1-(4-Chlorophenyl)-2,5-dioxopyrrolidin-3-yl]-N-(furan-2-ylmethyl)acetamide
CAS 1008865-59-5C17H15ClN2O4
4-{[1-(4-Fluorophenyl)-2,5-dioxopyrrolidin-3-yl](furan-2-ylmethyl)amino}-4-oxobutanoic acid chemical structure, C19H17FN2O6, CAS 340696-58-4
4-{[1-(4-Fluorophenyl)-2,5-dioxopyrrolidin-3-yl](furan-2-ylmethyl)amino}-4-oxobutanoic acid
CAS 340696-58-4C19H17FN2O6
N-[2,5-Dioxo-1-(4-propoxyphenyl)pyrrolidin-3-yl]-N-(furan-2-ylmethyl)propanamide chemical structure, C21H24N2O5, CAS 470695-27-3
N-[2,5-Dioxo-1-(4-propoxyphenyl)pyrrolidin-3-yl]-N-(furan-2-ylmethyl)propanamide
CAS 470695-27-3C21H24N2O5