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Murcko scaffold

N-(4-Phenyl-1,3-thiazol-2-yl)furan-2-carboxamide scaffold

36 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
36
With full pages
8
Scaffold SMILES

O=C(Nc1nc(-c2ccccc2)cs1)c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(4-Phenyl-1,3-thiazol-2-yl)furan-2-carboxamide page
Murcko scaffold O=C(Nc1nc(-c2ccccc2)cs1)c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

N-(4-Phenyl-1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H10N2O2S, CAS 15850-38-1
N-(4-Phenyl-1,3-thiazol-2-yl)furan-2-carboxamide
CAS 15850-38-1C14H10N2O2S
N-[4-(2,4-Dichlorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C14H8Cl2N2O2S, CAS 325981-40-6
N-[4-(2,4-Dichlorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 325981-40-6C14H8Cl2N2O2S
N-[4-(3-Nitrophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C14H9N3O4S, CAS 313404-12-5
N-[4-(3-Nitrophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 313404-12-5C14H9N3O4S
N-[4-(3,4-Dimethylphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C16H14N2O2S, CAS 312604-88-9
N-[4-(3,4-Dimethylphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 312604-88-9C16H14N2O2S
N-[4-(4-Chlorophenyl)-5-methyl-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C15H11ClN2O2S, CAS 333433-09-3
N-[4-(4-Chlorophenyl)-5-methyl-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 333433-09-3C15H11ClN2O2S
N-[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C14H8Cl2N2O2S, CAS 312925-46-5
N-[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 312925-46-5C14H8Cl2N2O2S
Ethyl 2-(furan-2-carboxamido)-4-phenylthiazole-5-carboxylate chemical structure, C17H14N2O4S, CAS 312605-07-5
Ethyl 2-(furan-2-carboxamido)-4-phenylthiazole-5-carboxylate
CAS 312605-07-5C17H14N2O4S
N-[4-(2,5-Dimethoxyphenyl)-5-methyl-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C17H16N2O4S, CAS 426244-52-2
N-[4-(2,5-Dimethoxyphenyl)-5-methyl-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 426244-52-2C17H16N2O4S
5-Methyl-N-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C15H11N3O4S, CAS 545346-80-3
5-Methyl-N-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 545346-80-3C15H11N3O4S
N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C14H9FN2O2S, CAS 325977-09-1
N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 325977-09-1C14H9FN2O2S
N-[4-(2,4-Dimethylphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C16H14N2O2S, CAS 312604-87-8
N-[4-(2,4-Dimethylphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 312604-87-8C16H14N2O2S
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-5-methylfuran-2-carboxamide chemical structure, C15H11ClN2O2S, CAS 353770-84-0
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-5-methylfuran-2-carboxamide
CAS 353770-84-0C15H11ClN2O2S
5-Bromo-N-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C14H7BrCl2N2O2S, CAS 541522-84-3
5-Bromo-N-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 541522-84-3C14H7BrCl2N2O2S
N-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-5-methylfuran-2-carboxamide chemical structure, C15H11BrN2O2S, CAS 354996-93-3
N-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-5-methylfuran-2-carboxamide
CAS 354996-93-3C15H11BrN2O2S
5-Bromo-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C14H8BrClN2O2S, CAS 433954-27-9
5-Bromo-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 433954-27-9C14H8BrClN2O2S
N-[4-(3-Bromo-4-methoxyphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C15H11BrN2O3S, CAS 354156-80-2
N-[4-(3-Bromo-4-methoxyphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 354156-80-2C15H11BrN2O3S
Ethyl 2-{2-[(2-furylcarbonyl)amino]-1,3-thiazol-4-yl}benzenecarboxylate chemical structure, C17H14N2O4S, CAS 250713-93-0
Ethyl 2-{2-[(2-furylcarbonyl)amino]-1,3-thiazol-4-yl}benzenecarboxylate
CAS 250713-93-0C17H14N2O4S
N-[4-(4-Propoxyphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C17H16N2O3S, CAS 15850-56-3
N-[4-(4-Propoxyphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 15850-56-3C17H16N2O3S
5-Bromo-N-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C16H13BrN2O4S, CAS 722472-01-7
5-Bromo-N-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 722472-01-7C16H13BrN2O4S
N-[4-(4-Bromophenyl)-5-propyl-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C17H15BrN2O2S, CAS 428459-92-1
N-[4-(4-Bromophenyl)-5-propyl-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 428459-92-1C17H15BrN2O2S
N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C15H12N2O3S, CAS 15850-44-9
N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 15850-44-9C15H12N2O3S
N-[4-(2,5-Dichlorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide chemical structure, C14H8Cl2N2O2S, CAS 325988-01-0
N-[4-(2,5-Dichlorophenyl)-1,3-thiazol-2-yl]furan-2-carboxamide
CAS 325988-01-0C14H8Cl2N2O2S
N-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]-5-nitrofuran-2-carboxamide chemical structure, C15H11N3O4S, CAS 92498-86-7
N-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]-5-nitrofuran-2-carboxamide
CAS 92498-86-7C15H11N3O4S
N-(4-(4-Cyanophenyl)thiazol-2-yl)furan-2-carboxamide chemical structure, C15H9N3O2S, CAS 476280-43-0
N-(4-(4-Cyanophenyl)thiazol-2-yl)furan-2-carboxamide
CAS 476280-43-0C15H9N3O2S