CompoundList
Sign in
Murcko scaffold

5-Oxo-1-phenyl-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide scaffold

59 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
59
With full pages
14
Scaffold SMILES

O=C(Nc1nccs1)C1CC(=O)N(c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Oxo-1-phenyl-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide page
Murcko scaffold O=C(Nc1nccs1)C1CC(=O)N(c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

1-(4-Methylphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C15H15N3O2S, CAS 332026-54-7
1-(4-Methylphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 332026-54-7C15H15N3O2S
1-(4-Chlorophenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C14H12ClN3O2S, CAS 330451-11-1
1-(4-Chlorophenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 330451-11-1C14H12ClN3O2S
5-Oxo-1-phenyl-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C14H13N3O2S, CAS 296801-25-7
5-Oxo-1-phenyl-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 296801-25-7C14H13N3O2S
5-Oxo-1-(4-propoxyphenyl)-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C17H19N3O3S, CAS 496940-38-6
5-Oxo-1-(4-propoxyphenyl)-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 496940-38-6C17H19N3O3S
1-(4-Methoxyphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C15H15N3O3S, CAS 641585-37-7
1-(4-Methoxyphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 641585-37-7C15H15N3O3S
5-Oxo-1-(4-propan-2-ylphenyl)-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C17H19N3O2S, CAS 444145-30-6
5-Oxo-1-(4-propan-2-ylphenyl)-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 444145-30-6C17H19N3O2S
1-(4-Methylphenyl)-N-(5-nitro-1,3-thiazol-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C15H14N4O4S, CAS 825597-74-8
1-(4-Methylphenyl)-N-(5-nitro-1,3-thiazol-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 825597-74-8C15H14N4O4S
1-(3-Chloro-4-methylphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C15H14ClN3O2S, CAS 713081-25-5
1-(3-Chloro-4-methylphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 713081-25-5C15H14ClN3O2S
1-(3-Methoxyphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C15H15N3O3S, CAS 713081-69-7
1-(3-Methoxyphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 713081-69-7C15H15N3O3S
1-(5-Chloro-2-methoxyphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C15H14ClN3O3S, CAS 713081-80-2
1-(5-Chloro-2-methoxyphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 713081-80-2C15H14ClN3O3S
1-(2-Chlorophenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C14H12ClN3O2S, CAS 713082-60-1
1-(2-Chlorophenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 713082-60-1C14H12ClN3O2S
1-(3-Chlorophenyl)-5-oxo-N-(1,3-thiazol-2-yl)-3-pyrrolidinecarboxamide chemical structure, C14H12ClN3O2S, CAS 774547-61-4
1-(3-Chlorophenyl)-5-oxo-N-(1,3-thiazol-2-yl)-3-pyrrolidinecarboxamide
CAS 774547-61-4C14H12ClN3O2S
1-(3-Chloro-2-methylphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C15H14ClN3O2S, CAS 312517-02-5
1-(3-Chloro-2-methylphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 312517-02-5C15H14ClN3O2S
1-(4-Fluorophenyl)-5-oxo-N-(1,3-thiazol-2-yl)-3-pyrrolidinecarboxamide chemical structure, C14H12FN3O2S, CAS 311791-19-2
1-(4-Fluorophenyl)-5-oxo-N-(1,3-thiazol-2-yl)-3-pyrrolidinecarboxamide
CAS 311791-19-2C14H12FN3O2S
1-(3,5-Dimethylphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C16H17N3O2S, CAS 774547-65-8
1-(3,5-Dimethylphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 774547-65-8C16H17N3O2S
1-(2,3-Dimethylphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C16H17N3O2S, CAS 876715-80-9
1-(2,3-Dimethylphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 876715-80-9C16H17N3O2S
1-[3-Methyl-4-(1-methylethyl)phenyl]-5-oxo-N-2-thiazolyl-3-pyrrolidinecarboxamide chemical structure, C18H21N3O2S, CAS 866153-54-0
1-[3-Methyl-4-(1-methylethyl)phenyl]-5-oxo-N-2-thiazolyl-3-pyrrolidinecarboxamide
CAS 866153-54-0C18H21N3O2S
1-(2-Methoxyphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C15H15N3O3S, CAS 847590-16-3
1-(2-Methoxyphenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 847590-16-3C15H15N3O3S
1-(4-Bromophenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C14H12BrN3O2S, CAS 383172-79-0
1-(4-Bromophenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 383172-79-0C14H12BrN3O2S
1-(4-Chlorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C15H14ClN3O2S, CAS 879601-83-9
1-(4-Chlorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 879601-83-9C15H14ClN3O2S
1-(2-Fluorophenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide chemical structure, C14H12FN3O2S, CAS 873565-15-2
1-(2-Fluorophenyl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
CAS 873565-15-2C14H12FN3O2S
1-(4-Fluorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C15H14FN3O2S, CAS 878731-13-6
1-(4-Fluorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 878731-13-6C15H14FN3O2S
1-(2-Fluorophenyl)-N-(5-methyl-1,3-thiazol-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C15H14FN3O2S, CAS 915933-54-9
1-(2-Fluorophenyl)-N-(5-methyl-1,3-thiazol-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 915933-54-9C15H14FN3O2S
1-(2-Methylphenyl)-N-(4-methyl-1,3-thiazol-2-yl)-5-oxopyrrolidine-3-carboxamide chemical structure, C16H17N3O2S, CAS 896921-40-7
1-(2-Methylphenyl)-N-(4-methyl-1,3-thiazol-2-yl)-5-oxopyrrolidine-3-carboxamide
CAS 896921-40-7C16H17N3O2S