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Murcko scaffold

Ring system with 3 rings and 19 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
18
With full pages
10
Scaffold SMILES

O=C(Nc1nccs1)c1ccc(-c2ccccc2)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nccs1)c1ccc(-c2ccccc2)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

5-(2,4-Dichlorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H8Cl2N2O2S, CAS 618414-26-9
5-(2,4-Dichlorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 618414-26-9C14H8Cl2N2O2S
5-(3-Chloro-2-methylphenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C15H11ClN2O2S, CAS 347314-16-3
5-(3-Chloro-2-methylphenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 347314-16-3C15H11ClN2O2S
5-(2-Chlorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C15H11ClN2O2S, CAS 618401-92-6
5-(2-Chlorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)furan-2-carboxamide
CAS 618401-92-6C15H11ClN2O2S
5-(3-Nitrophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H9N3O4S, CAS 618418-45-4
5-(3-Nitrophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 618418-45-4C14H9N3O4S
5-(4-Nitrophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H9N3O4S, CAS 618405-48-4
5-(4-Nitrophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 618405-48-4C14H9N3O4S
5-(2-Chlorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H9ClN2O2S, CAS 199459-00-2
5-(2-Chlorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 199459-00-2C14H9ClN2O2S
5-(4-Chlorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H9ClN2O2S, CAS 213911-09-2
5-(4-Chlorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 213911-09-2C14H9ClN2O2S
5-(4-Fluorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H9FN2O2S, CAS 831184-55-5
5-(4-Fluorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 831184-55-5C14H9FN2O2S
5-[2-Chloro-5-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C15H8ClF3N2O2S, CAS 831230-68-3
5-[2-Chloro-5-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 831230-68-3C15H8ClF3N2O2S
5-(4-Bromophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H9BrN2O2S, CAS 874464-09-2
5-(4-Bromophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 874464-09-2C14H9BrN2O2S
5-(3-Chloro-4-fluorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H8ClFN2O2S, CAS 874464-10-5
5-(3-Chloro-4-fluorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 874464-10-5C14H8ClFN2O2S
5-(4-Chloro-2-nitrophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H8ClN3O4S, CAS 881428-58-6
5-(4-Chloro-2-nitrophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 881428-58-6C14H8ClN3O4S
N-(1,3-Thiazol-2-yl)-5-[2-(trifluoromethyl)phenyl]furan-2-carboxamide chemical structure, C15H9F3N2O2S, CAS 620541-29-9
N-(1,3-Thiazol-2-yl)-5-[2-(trifluoromethyl)phenyl]furan-2-carboxamide
CAS 620541-29-9C15H9F3N2O2S
5-(3,4-Dichlorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H8Cl2N2O2S, CAS 618405-41-7
5-(3,4-Dichlorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 618405-41-7C14H8Cl2N2O2S
5-(2-Fluorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C14H9FN2O2S, CAS 878983-33-6
5-(2-Fluorophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 878983-33-6C14H9FN2O2S
N-(5-Methyl-1,3-thiazol-2-yl)-5-(4-nitrophenyl)furan-2-carboxamide chemical structure, C15H11N3O4S, CAS 852684-73-2
N-(5-Methyl-1,3-thiazol-2-yl)-5-(4-nitrophenyl)furan-2-carboxamide
CAS 852684-73-2C15H11N3O4S
5-(4-Methoxy-2-nitrophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C15H11N3O5S, CAS 887348-52-9
5-(4-Methoxy-2-nitrophenyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 887348-52-9C15H11N3O5S
Ethyl [2-({[5-(2-chlorophenyl)furan-2-yl]carbonyl}amino)-1,3-thiazol-4-yl]acetate chemical structure, C18H15ClN2O4S, CAS 1010978-38-7
Ethyl [2-({[5-(2-chlorophenyl)furan-2-yl]carbonyl}amino)-1,3-thiazol-4-yl]acetate
CAS 1010978-38-7C18H15ClN2O4S