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Murcko scaffold

4-Phenoxyquinoline scaffold

228 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
228
With full pages
5
Scaffold SMILES

c1ccc(Oc2ccnc3ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenoxyquinoline page
Murcko scaffold c1ccc(Oc2ccnc3ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 228 chemicals

8-Chloro-4-(2-chloro-4-fluorophenoxy)quinoline chemical structure, C15H8Cl2FNO, CAS 124495-31-4
8-Chloro-4-(2-chloro-4-fluorophenoxy)quinoline
CAS 124495-31-4C15H8Cl2FNO
7-Chloro-4-(4-fluorophenoxy)quinoline chemical structure, C15H9ClFNO, CAS 124495-00-7
7-Chloro-4-(4-fluorophenoxy)quinoline
CAS 124495-00-7C15H9ClFNO
7-Chloro-4-(2-nitrophenoxy)quinoline chemical structure, C15H9ClN2O3, CAS 124495-54-1
7-Chloro-4-(2-nitrophenoxy)quinoline
CAS 124495-54-1C15H9ClN2O3
Quinoline, 7-chloro-4-(2-(trifluoromethyl)phenoxy)- chemical structure, C16H9ClF3NO, CAS 124495-56-3
Quinoline, 7-chloro-4-(2-(trifluoromethyl)phenoxy)-
CAS 124495-56-3C16H9ClF3NO
8-Chloro-4-(2-methylphenoxy)quinoline chemical structure, C16H12ClNO, CAS 124496-00-0
8-Chloro-4-(2-methylphenoxy)quinoline
CAS 124496-00-0C16H12ClNO
8-Chloro-4-(2-chlorophenoxy)quinoline chemical structure, C15H9Cl2NO, CAS 124497-46-7
8-Chloro-4-(2-chlorophenoxy)quinoline
CAS 124497-46-7C15H9Cl2NO
4-(4-Chlorophenoxy)-6-methoxy-8-nitroquinoline chemical structure, C16H11ClN2O4, CAS 63456-77-9
4-(4-Chlorophenoxy)-6-methoxy-8-nitroquinoline
CAS 63456-77-9C16H11ClN2O4
2,6-Dimethyl-4-(3-methylphenoxy)quinoline chemical structure, C18H17NO, CAS 307545-70-6
2,6-Dimethyl-4-(3-methylphenoxy)quinoline
CAS 307545-70-6C18H17NO
Ethyl 8-methoxy-4-phenoxyquinoline-3-carboxylate chemical structure, C19H17NO4, CAS 477847-18-0
Ethyl 8-methoxy-4-phenoxyquinoline-3-carboxylate
CAS 477847-18-0C19H17NO4
Ethyl 4-(4-fluorophenoxy)-8-methoxyquinoline-3-carboxylate chemical structure, C19H16FNO4, CAS 477847-19-1
Ethyl 4-(4-fluorophenoxy)-8-methoxyquinoline-3-carboxylate
CAS 477847-19-1C19H16FNO4
Ethyl 8-fluoro-4-[3-(trifluoromethyl)phenoxy]quinoline-3-carboxylate chemical structure, C19H13F4NO3, CAS 477847-21-5
Ethyl 8-fluoro-4-[3-(trifluoromethyl)phenoxy]quinoline-3-carboxylate
CAS 477847-21-5C19H13F4NO3
Ethyl 8-fluoro-4-[2-(methoxycarbonyl)phenoxy]-3-quinolinecarboxylate chemical structure, C20H16FNO5, CAS 477847-22-6
Ethyl 8-fluoro-4-[2-(methoxycarbonyl)phenoxy]-3-quinolinecarboxylate
CAS 477847-22-6C20H16FNO5
8-Bromo-4-phenoxy-2-(trifluoromethyl)quinoline chemical structure, C16H9BrF3NO, CAS 4763-93-3
8-Bromo-4-phenoxy-2-(trifluoromethyl)quinoline
CAS 4763-93-3C16H9BrF3NO
Quinoxyfen chemical structure, C15H8Cl2FNO, CAS 124495-18-7
Quinoxyfen
CAS 124495-18-7C15H8Cl2FNO
N-{2-Chloro-4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl}-N'-propylurea chemical structure, C21H22ClN3O4, CAS 286369-64-0
N-{2-Chloro-4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl}-N'-propylurea
CAS 286369-64-0C21H22ClN3O4
6,7-Dimethoxy-4-(3,4-dimethoxyphenoxy)quinoline chemical structure, C19H19NO5, CAS 190726-45-5
6,7-Dimethoxy-4-(3,4-dimethoxyphenoxy)quinoline
CAS 190726-45-5C19H19NO5
Ethanone, 1-[3-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]- chemical structure, C19H17NO4, CAS 651054-43-2
Ethanone, 1-[3-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-
CAS 651054-43-2C19H17NO4
4-[3-Chloro-4-[[(ethylamino)carbonyl]amino]phenoxy]-N,7-dimethoxy-6-quinolinecarboxamide chemical structure, C21H21ClN4O5, CAS 417720-53-7
4-[3-Chloro-4-[[(ethylamino)carbonyl]amino]phenoxy]-N,7-dimethoxy-6-quinolinecarboxamide
CAS 417720-53-7C21H21ClN4O5
1-(2-((6,7-Dimethoxyquinolin-4-yl)oxy)-4,5-dimethylphenyl)ethan-1-one chemical structure, C21H21NO4, CAS 666729-57-3
1-(2-((6,7-Dimethoxyquinolin-4-yl)oxy)-4,5-dimethylphenyl)ethan-1-one
CAS 666729-57-3C21H21NO4
4-[3-Chloro-4-[[(ethylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide chemical structure, C20H19ClN4O4, CAS 417719-46-1
4-[3-Chloro-4-[[(ethylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide
CAS 417719-46-1C20H19ClN4O4
4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2-chloroaniline chemical structure, C17H15ClN2O3, CAS 286371-44-6
4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2-chloroaniline
CAS 286371-44-6C17H15ClN2O3
4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2-fluoroaniline chemical structure, C17H15FN2O3, CAS 228559-74-8
4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2-fluoroaniline
CAS 228559-74-8C17H15FN2O3
4-(3-Fluoro-4-nitrophenoxy)-6,7-dimethoxyquinoline chemical structure, C17H13FN2O5, CAS 228559-87-3
4-(3-Fluoro-4-nitrophenoxy)-6,7-dimethoxyquinoline
CAS 228559-87-3C17H13FN2O5
4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorobenzenamine chemical structure, C17H15FN2O3, CAS 347161-74-4
4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorobenzenamine
CAS 347161-74-4C17H15FN2O3