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Murcko scaffold

Ring system with 2 rings and 14 atoms

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
11
With full pages
1
Scaffold SMILES

O=c1cccc(Nc2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cccc(Nc2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

5-Fluoro-2-(2-fluoro-4-methylsulfanylanilino)-N-[(2S)-2-hydroxypropoxy]-1-methyl-6-oxopyridine-3-carboxamide chemical structure, C17H19F2N3O4S, CAS 934639-60-8
5-Fluoro-2-(2-fluoro-4-methylsulfanylanilino)-N-[(2S)-2-hydroxypropoxy]-1-methyl-6-oxopyridine-3-carboxamide
CAS 934639-60-8C17H19F2N3O4S
Azd-8330 chemical structure, C16H17FIN3O4, CAS 869357-68-6
Azd-8330
CAS 869357-68-6C16H17FIN3O4
2-(4-Bromo-2-fluorophenylamino)-6-oxo-1,6-dihydropyridine-3-carboxylic acid chemical structure, C12H8BrFN2O3, CAS 853109-54-3
2-(4-Bromo-2-fluorophenylamino)-6-oxo-1,6-dihydropyridine-3-carboxylic acid
CAS 853109-54-3C12H8BrFN2O3
Methyl 2-(2-fluoro-4-iodophenylamino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylate chemical structure, C15H14FIN2O3, CAS 869357-67-5
Methyl 2-(2-fluoro-4-iodophenylamino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylate
CAS 869357-67-5C15H14FIN2O3
Methyl 2-(4-bromo-2-fluorophenylamino)-5-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate chemical structure, C14H11BrClFN2O3, CAS 869357-72-2
Methyl 2-(4-bromo-2-fluorophenylamino)-5-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate
CAS 869357-72-2C14H11BrClFN2O3
2-Chloro-5-((1-methyl-6-oxo-1,6-dihydro-pyridin-2-yl)amino)-benzoic acid methyl ester chemical structure, C14H13ClN2O3, CAS 1394348-36-7
2-Chloro-5-((1-methyl-6-oxo-1,6-dihydro-pyridin-2-yl)amino)-benzoic acid methyl ester
CAS 1394348-36-7C14H13ClN2O3
2-Chloro-5-((1-methyl-6-oxo-1,6-dihydro-pyridin-2-yl)amino)-benzoic acid chemical structure, C13H11ClN2O3, CAS 1394348-37-8
2-Chloro-5-((1-methyl-6-oxo-1,6-dihydro-pyridin-2-yl)amino)-benzoic acid
CAS 1394348-37-8C13H11ClN2O3
5-Amino-6-((2-fluoro-4-iodophenyl)amino)-1,3-dimethylpyridin-2(1H)-one chemical structure, C13H13FIN3O, CAS 1258884-12-6
5-Amino-6-((2-fluoro-4-iodophenyl)amino)-1,3-dimethylpyridin-2(1H)-one
CAS 1258884-12-6C13H13FIN3O
6-(2-Fluoro-4-iodoanilino)-4-methoxy-5-nitro-1H-pyridin-2-one chemical structure, C12H9FIN3O4, CAS 1258884-28-4
6-(2-Fluoro-4-iodoanilino)-4-methoxy-5-nitro-1H-pyridin-2-one
CAS 1258884-28-4C12H9FIN3O4
2-Chloro-5-[(1-(2-methoxy-ethyl)-6-oxo-1,6-dihydro-pyridin-2-yl)amino]-benzoic acid chemical structure, C15H15ClN2O4, CAS 1394348-41-4
2-Chloro-5-[(1-(2-methoxy-ethyl)-6-oxo-1,6-dihydro-pyridin-2-yl)amino]-benzoic acid
CAS 1394348-41-4C15H15ClN2O4
2-Chloro-5-[(1-(2-methoxy-ethyl)-6-oxo-1,6-dihydro-pyridin-2-yl)amino]-benzoic acid methyl ester chemical structure, C16H17ClN2O4, CAS 1394348-40-3
2-Chloro-5-[(1-(2-methoxy-ethyl)-6-oxo-1,6-dihydro-pyridin-2-yl)amino]-benzoic acid methyl ester
CAS 1394348-40-3C16H17ClN2O4