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Murcko scaffold

Ring system with 3 rings and 19 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
7
With full pages
1
Scaffold SMILES

O=C(NCc1ccc2c(c1)OCO2)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccc2c(c1)OCO2)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

N-(1,3-Benzodioxol-5-ylmethyl)-2-chloro-3-pyridinecarboxamide chemical structure, C14H11ClN2O3, CAS 545350-52-5
N-(1,3-Benzodioxol-5-ylmethyl)-2-chloro-3-pyridinecarboxamide
CAS 545350-52-5C14H11ClN2O3
N-(1,3-Benzodioxol-5-ylmethyl)-2-methylsulfanylpyridine-3-carboxamide chemical structure, C15H14N2O3S, CAS 775310-14-0
N-(1,3-Benzodioxol-5-ylmethyl)-2-methylsulfanylpyridine-3-carboxamide
CAS 775310-14-0C15H14N2O3S
N-[(1,3-Dioxaindan-5-yl)methyl]-6-chloropyridine-3-carboxamide chemical structure, C14H11ClN2O3, CAS 786715-32-0
N-[(1,3-Dioxaindan-5-yl)methyl]-6-chloropyridine-3-carboxamide
CAS 786715-32-0C14H11ClN2O3
N-[1-(1,3-Dioxaindan-5-yl)ethyl]-2-(methylsulfanyl)pyridine-3-carboxamide chemical structure, C16H16N2O3S, CAS 1061328-01-5
N-[1-(1,3-Dioxaindan-5-yl)ethyl]-2-(methylsulfanyl)pyridine-3-carboxamide
CAS 1061328-01-5C16H16N2O3S
N-[(1,3-Dioxaindan-5-yl)methyl]-N-methyl-2-(methylsulfanyl)pyridine-3-carboxamide chemical structure, C16H16N2O3S, CAS 1090692-07-1
N-[(1,3-Dioxaindan-5-yl)methyl]-N-methyl-2-(methylsulfanyl)pyridine-3-carboxamide
CAS 1090692-07-1C16H16N2O3S
N-[(1,3-Dioxaindan-5-yl)methyl]-N-ethyl-6-fluoropyridine-3-carboxamide chemical structure, C16H15FN2O3, CAS 1333742-32-7
N-[(1,3-Dioxaindan-5-yl)methyl]-N-ethyl-6-fluoropyridine-3-carboxamide
CAS 1333742-32-7C16H15FN2O3
N-[(2H-1,3-Benzodioxol-5-yl)methyl]-2-bromo-6-methylpyridine-3-carboxamide chemical structure, C15H13BrN2O3, CAS 1427982-02-2
N-[(2H-1,3-Benzodioxol-5-yl)methyl]-2-bromo-6-methylpyridine-3-carboxamide
CAS 1427982-02-2C15H13BrN2O3