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Murcko scaffold

3-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2-propen-1-one scaffold

17 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 19
Chemicals: 17
With full pages: 5

Scaffold SMILES

O=C(C=Cc1ccc2c(c1)OCO2)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 3-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2-propen-1-one page

Murcko scaffold O=C(C=Cc1ccc2c(c1)OCO2)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

3-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2-propen-1-one chemical structure, C15H17NO3, CAS 23434-86-8

3-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2-propen-1-one

CAS 23434-86-8C₁₅H₁₇NO₃

Ilepcimide chemical structure, C15H17NO3, CAS 82857-82-7

CAS 82857-82-7C₁₅H₁₇NO₃

3-Benzo[1,3]dioxol-5-yl-1-(4-methyl-piperidin-1-yl)-propenone chemical structure, C16H19NO3, CAS 290835-22-2

3-Benzo[1,3]dioxol-5-yl-1-(4-methyl-piperidin-1-yl)-propenone

CAS 290835-22-2C₁₆H₁₉NO₃

1-(3-Benzo[1,3]dioxol-5-yl-acryloyl)-piperidine-4-carboxylic acid methyl ester chemical structure, C17H19NO5, CAS 349541-64-6

1-(3-Benzo[1,3]dioxol-5-yl-acryloyl)-piperidine-4-carboxylic acid methyl ester

CAS 349541-64-6C₁₇H₁₉NO₅

1-{2-[(1,3-Dioxaindan-5-yl)methylidene]-2-cyanoacetyl}piperidine-4-carboxamide chemical structure, C17H17N3O4, CAS 721433-90-5

1-{2-[(1,3-Dioxaindan-5-yl)methylidene]-2-cyanoacetyl}piperidine-4-carboxamide

CAS 721433-90-5C₁₇H₁₇N₃O₄

3-(1,3-Benzodioxol-5-yl)-2-(2,6-dimethylpiperidine-1-carbonyl)prop-2-enenitrile chemical structure, C18H20N2O3

3-(1,3-Benzodioxol-5-yl)-2-(2,6-dimethylpiperidine-1-carbonyl)prop-2-enenitrile

C₁₈H₂₀N₂O₃

(E)-3-(1,3-Benzodioxol-5-yl)-1-(3,5-dimethylpiperidin-1-yl)prop-2-en-1-one chemical structure, C17H21NO3, CAS 349578-04-7

(E)-3-(1,3-Benzodioxol-5-yl)-1-(3,5-dimethylpiperidin-1-yl)prop-2-en-1-one

CAS 349578-04-7C₁₇H₂₁NO₃

Ethyl 1-[(2E)-3-(1,3-benzodioxol-5-yl)prop-2-enoyl]piperidine-3-carboxylate chemical structure, C18H21NO5, CAS 349541-60-2

Ethyl 1-[(2E)-3-(1,3-benzodioxol-5-yl)prop-2-enoyl]piperidine-3-carboxylate

CAS 349541-60-2C₁₈H₂₁NO₅

(E)-3-(1,3-Benzodioxol-5-yl)-1-(2-methylpiperidin-1-yl)prop-2-en-1-one chemical structure, C16H19NO3, CAS 349427-24-3

(E)-3-(1,3-Benzodioxol-5-yl)-1-(2-methylpiperidin-1-yl)prop-2-en-1-one

CAS 349427-24-3C₁₆H₁₉NO₃

(E)-3-(1,3-Benzodioxol-5-yl)-2-(2,6-dimethylpiperidine-1-carbonyl)prop-2-enenitrile chemical structure, C18H20N2O3

(E)-3-(1,3-Benzodioxol-5-yl)-2-(2,6-dimethylpiperidine-1-carbonyl)prop-2-enenitrile

C₁₈H₂₀N₂O₃

(2E)-3-(1,3-Benzodioxol-5-yl)-1-(2-ethylpiperidin-1-yl)prop-2-en-1-one chemical structure, C17H21NO3, CAS 300825-58-5

(2E)-3-(1,3-Benzodioxol-5-yl)-1-(2-ethylpiperidin-1-yl)prop-2-en-1-one

CAS 300825-58-5C₁₇H₂₁NO₃

Z-Antiepilepsirine chemical structure, C15H17NO3, CAS 111479-04-0

Z-Antiepilepsirine

CAS 111479-04-0C₁₅H₁₇NO₃

(E)-3-(Benzo[d][1,3]dioxol-5-yl)-1-(4-(methylsulfonyl)piperidin-1-yl)prop-2-en-1-one chemical structure, C16H19NO5S, CAS 1448139-40-9

(E)-3-(Benzo[d][1,3]dioxol-5-yl)-1-(4-(methylsulfonyl)piperidin-1-yl)prop-2-en-1-one

CAS 1448139-40-9C₁₆H₁₉NO₅S

(E)-2-((1-(3-(Benzo[d][1,3]dioxol-5-yl)acryloyl)piperidin-4-yl)sulfonyl)-N-methylacetamide chemical structure, C18H22N2O6S, CAS 1798414-76-2

(E)-2-((1-(3-(Benzo[d][1,3]dioxol-5-yl)acryloyl)piperidin-4-yl)sulfonyl)-N-methylacetamide

CAS 1798414-76-2C₁₈H₂₂N₂O₆S

(E)-Methyl 2-((1-(3-(benzo[d][1,3]dioxol-5-yl)acryloyl)piperidin-4-yl)sulfonyl)acetate chemical structure, C18H21NO7S, CAS 2097940-10-6

(E)-Methyl 2-((1-(3-(benzo[d][1,3]dioxol-5-yl)acryloyl)piperidin-4-yl)sulfonyl)acetate

CAS 2097940-10-6C₁₈H₂₁NO₇S

(Z)-3-(1,3-Benzodioxol-5-yl)-2-(2,6-dimethylpiperidine-1-carbonyl)prop-2-enenitrile chemical structure, C18H20N2O3, CAS 380560-95-2

(Z)-3-(1,3-Benzodioxol-5-yl)-2-(2,6-dimethylpiperidine-1-carbonyl)prop-2-enenitrile

CAS 380560-95-2C₁₈H₂₀N₂O₃

(2E)-3-(2H-1,3-Benzodioxol-5-yl)-1-(4,4-difluoropiperidin-1-yl)prop-2-en-1-one chemical structure, C15H15F2NO3, CAS 2348614-10-6

(2E)-3-(2H-1,3-Benzodioxol-5-yl)-1-(4,4-difluoropiperidin-1-yl)prop-2-en-1-one

CAS 2348614-10-6C₁₅H₁₅F₂NO₃