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Murcko scaffold

Ring system with 3 rings and 19 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
20
With full pages
5
Scaffold SMILES

S=C(Nc1ccccc1)Nc1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=C(Nc1ccccc1)Nc1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

Ethyl 3-(3-phenylthioureido)-1H-indole-2-carboxylate chemical structure, C18H17N3O2S, CAS 116989-29-8
Ethyl 3-(3-phenylthioureido)-1H-indole-2-carboxylate
CAS 116989-29-8C18H17N3O2S
Ethyl 3-[(4-fluorophenyl)carbamothioylamino]-1H-indole-2-carboxylate chemical structure, C18H16FN3O2S, CAS 160424-51-1
Ethyl 3-[(4-fluorophenyl)carbamothioylamino]-1H-indole-2-carboxylate
CAS 160424-51-1C18H16FN3O2S
Ethyl 3-(3-(o-tolyl)thioureido)-1H-indole-2-carboxylate chemical structure, C19H19N3O2S, CAS 686736-55-0
Ethyl 3-(3-(o-tolyl)thioureido)-1H-indole-2-carboxylate
CAS 686736-55-0C19H19N3O2S
Ethyl 3-(3-(m-tolyl)thioureido)-1H-indole-2-carboxylate chemical structure, C19H19N3O2S, CAS 686736-56-1
Ethyl 3-(3-(m-tolyl)thioureido)-1H-indole-2-carboxylate
CAS 686736-56-1C19H19N3O2S
3-[[(2,3-Dimethylanilino)-sulfanylidenemethyl]amino]-1H-indole-2-carboxylic acid ethyl ester chemical structure, C20H21N3O2S, CAS 686736-57-2
3-[[(2,3-Dimethylanilino)-sulfanylidenemethyl]amino]-1H-indole-2-carboxylic acid ethyl ester
CAS 686736-57-2C20H21N3O2S
Ethyl 3-[(2,5-dimethylphenyl)carbamothioylamino]-1H-indole-2-carboxylate chemical structure, C20H21N3O2S, CAS 686736-58-3
Ethyl 3-[(2,5-dimethylphenyl)carbamothioylamino]-1H-indole-2-carboxylate
CAS 686736-58-3C20H21N3O2S
Ethyl 3-(3-(2-methoxyphenyl)thioureido)-1H-indole-2-carboxylate chemical structure, C19H19N3O3S, CAS 686736-59-4
Ethyl 3-(3-(2-methoxyphenyl)thioureido)-1H-indole-2-carboxylate
CAS 686736-59-4C19H19N3O3S
Ethyl 3-(3-(4-methoxyphenyl)thioureido)-1H-indole-2-carboxylate chemical structure, C19H19N3O3S, CAS 686736-60-7
Ethyl 3-(3-(4-methoxyphenyl)thioureido)-1H-indole-2-carboxylate
CAS 686736-60-7C19H19N3O3S
Ethyl 3-[(2,5-dimethoxyphenyl)carbamothioylamino]-1H-indole-2-carboxylate chemical structure, C20H21N3O4S, CAS 686736-61-8
Ethyl 3-[(2,5-dimethoxyphenyl)carbamothioylamino]-1H-indole-2-carboxylate
CAS 686736-61-8C20H21N3O4S
Ethyl 3-(3-(4-ethoxyphenyl)thioureido)-1H-indole-2-carboxylate chemical structure, C20H21N3O3S, CAS 686736-62-9
Ethyl 3-(3-(4-ethoxyphenyl)thioureido)-1H-indole-2-carboxylate
CAS 686736-62-9C20H21N3O3S
Ethyl 3-[(3-fluorophenyl)carbamothioylamino]-1H-indole-2-carboxylate chemical structure, C18H16FN3O2S, CAS 160424-53-3
Ethyl 3-[(3-fluorophenyl)carbamothioylamino]-1H-indole-2-carboxylate
CAS 160424-53-3C18H16FN3O2S
Ethyl 3-(3-(2-chlorophenyl)thioureido)-1H-indole-2-carboxylate chemical structure, C18H16ClN3O2S, CAS 686736-63-0
Ethyl 3-(3-(2-chlorophenyl)thioureido)-1H-indole-2-carboxylate
CAS 686736-63-0C18H16ClN3O2S
Ethyl 3-(3-(4-chlorophenyl)thioureido)-1H-indole-2-carboxylate chemical structure, C18H16ClN3O2S, CAS 160424-49-7
Ethyl 3-(3-(4-chlorophenyl)thioureido)-1H-indole-2-carboxylate
CAS 160424-49-7C18H16ClN3O2S
Ethyl 3-(3-(3,4-dichlorophenyl)thioureido)-1H-indole-2-carboxylate chemical structure, C18H15Cl2N3O2S, CAS 686736-64-1
Ethyl 3-(3-(3,4-dichlorophenyl)thioureido)-1H-indole-2-carboxylate
CAS 686736-64-1C18H15Cl2N3O2S
Ethyl 3-[(3-chloro-2-methylphenyl)carbamothioylamino]-1H-indole-2-carboxylate chemical structure, C19H18ClN3O2S, CAS 686736-65-2
Ethyl 3-[(3-chloro-2-methylphenyl)carbamothioylamino]-1H-indole-2-carboxylate
CAS 686736-65-2C19H18ClN3O2S
Ethyl 3-(3-(3-bromophenyl)thioureido)-1H-indole-2-carboxylate chemical structure, C18H16BrN3O2S, CAS 686736-66-3
Ethyl 3-(3-(3-bromophenyl)thioureido)-1H-indole-2-carboxylate
CAS 686736-66-3C18H16BrN3O2S
Ethyl 3-(3-(4-bromophenyl)thioureido)-1H-indole-2-carboxylate chemical structure, C18H16BrN3O2S, CAS 160424-50-0
Ethyl 3-(3-(4-bromophenyl)thioureido)-1H-indole-2-carboxylate
CAS 160424-50-0C18H16BrN3O2S
Ethyl 3-(3-(3-(trifluoromethyl)phenyl)thioureido)-1H-indole-2-carboxylate chemical structure, C19H16F3N3O2S, CAS 160424-54-4
Ethyl 3-(3-(3-(trifluoromethyl)phenyl)thioureido)-1H-indole-2-carboxylate
CAS 160424-54-4C19H16F3N3O2S
Ethyl 3-(3-(4-(trifluoromethyl)phenyl)thioureido)-1H-indole-2-carboxylate chemical structure, C19H16F3N3O2S, CAS 686736-67-4
Ethyl 3-(3-(4-(trifluoromethyl)phenyl)thioureido)-1H-indole-2-carboxylate
CAS 686736-67-4C19H16F3N3O2S
Ethyl 3-[[4-(trifluoromethoxy)phenyl]carbamothioylamino]-1H-indole-2-carboxylate chemical structure, C19H16F3N3O3S, CAS 686736-68-5
Ethyl 3-[[4-(trifluoromethoxy)phenyl]carbamothioylamino]-1H-indole-2-carboxylate
CAS 686736-68-5C19H16F3N3O3S