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Murcko scaffold

4-(Piperidin-1-yl)quinoline scaffold

79 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
79
With full pages
3
Scaffold SMILES

c1ccc2c(N3CCCCC3)ccnc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Piperidin-1-yl)quinoline page
Murcko scaffold c1ccc2c(N3CCCCC3)ccnc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 79 chemicals

7-Chloro-4-(1-piperidinyl)quinoline chemical structure, C14H15ClN2, CAS 161467-87-4
7-Chloro-4-(1-piperidinyl)quinoline
CAS 161467-87-4C14H15ClN2
8-Nitro-4-piperidin-1-ylquinoline chemical structure, C14H15N3O2, CAS 714279-18-2
8-Nitro-4-piperidin-1-ylquinoline
CAS 714279-18-2C14H15N3O2
Quinoline, 2,8-dimethyl-4-(2-methyl-1-piperidinyl)- chemical structure, C17H22N2, CAS 87602-55-9
Quinoline, 2,8-dimethyl-4-(2-methyl-1-piperidinyl)-
CAS 87602-55-9C17H22N2
Quinoline, 8-methoxy-2-methyl-4-(2-methylpiperidino)- chemical structure, C17H22N2O, CAS 87602-61-7
Quinoline, 8-methoxy-2-methyl-4-(2-methylpiperidino)-
CAS 87602-61-7C17H22N2O
1-(7-Chloroquinolin-4-yl)piperidin-4-amine chemical structure, C14H16ClN3, CAS 893754-95-5
1-(7-Chloroquinolin-4-yl)piperidin-4-amine
CAS 893754-95-5C14H16ClN3
1-(6-Methoxy-2-methylquinolin-4-yl)piperidine-4-carboxamide chemical structure, C17H21N3O2, CAS 851185-21-2
1-(6-Methoxy-2-methylquinolin-4-yl)piperidine-4-carboxamide
CAS 851185-21-2C17H21N3O2
6-Quinolinecarboxylic acid, 2-methyl-4-(1-piperidinyl)- chemical structure, C16H18N2O2, CAS 900711-78-6
6-Quinolinecarboxylic acid, 2-methyl-4-(1-piperidinyl)-
CAS 900711-78-6C16H18N2O2
Ethyl 4-(4-methoxycarbonylpiperidin-1-yl)-7-(trifluoromethyl)quinoline-3-carboxylate chemical structure, C20H21F3N2O4, CAS 881932-77-0
Ethyl 4-(4-methoxycarbonylpiperidin-1-yl)-7-(trifluoromethyl)quinoline-3-carboxylate
CAS 881932-77-0C20H21F3N2O4
1-Quinolin-4-ylpiperidine-4-carboxylic acid chemical structure, C15H16N2O2, CAS 868077-41-2
1-Quinolin-4-ylpiperidine-4-carboxylic acid
CAS 868077-41-2C15H16N2O2
4-(Piperidin-1-yl)quinoline chemical structure, C14H16N2, CAS 14157-04-1
4-(Piperidin-1-yl)quinoline
CAS 14157-04-1C14H16N2
1-(2-Methylquinolin-4-yl)piperidin-4-ol chemical structure, C15H18N2O, CAS 927801-80-7
1-(2-Methylquinolin-4-yl)piperidin-4-ol
CAS 927801-80-7C15H18N2O
1-[7-(Trifluoromethyl)-4-quinolinyl]-4-piperidinecarboxamide chemical structure, C16H16F3N3O, CAS 392691-02-0
1-[7-(Trifluoromethyl)-4-quinolinyl]-4-piperidinecarboxamide
CAS 392691-02-0C16H16F3N3O
2-Methyl-4-(piperidin-1-yl)quinoline chemical structure, C15H18N2, CAS 82607-86-1
2-Methyl-4-(piperidin-1-yl)quinoline
CAS 82607-86-1C15H18N2
1-(6-Bromo-4-quinolyl)-4-piperidinecarboxylic acid chemical structure, C15H15BrN2O2, CAS 474707-34-1
1-(6-Bromo-4-quinolyl)-4-piperidinecarboxylic acid
CAS 474707-34-1C15H15BrN2O2
1-(6-Bromo-4-quinolyl)-4-piperidyl methyl ether chemical structure, C15H17BrN2O, CAS 474707-27-2
1-(6-Bromo-4-quinolyl)-4-piperidyl methyl ether
CAS 474707-27-2C15H17BrN2O
7-Chloro-4-(1-piperidinyl)quinoline hydrobromide chemical structure, C14H16BrClN2, CAS 853344-06-6
7-Chloro-4-(1-piperidinyl)quinoline hydrobromide
CAS 853344-06-6C14H16BrClN2
Ethyl 1-(6-chloro-3-cyanoquinolin-4-yl)piperidine-4-carboxylate chemical structure, C18H18ClN3O2, CAS 1040676-42-3
Ethyl 1-(6-chloro-3-cyanoquinolin-4-yl)piperidine-4-carboxylate
CAS 1040676-42-3C18H18ClN3O2
Ethyl 1-(3-cyano-7-methoxyquinolin-4-yl)piperidine-4-carboxylate chemical structure, C19H21N3O3, CAS 1040653-20-0
Ethyl 1-(3-cyano-7-methoxyquinolin-4-yl)piperidine-4-carboxylate
CAS 1040653-20-0C19H21N3O3
Ethyl 1-(3-cyano-6-ethoxyquinolin-4-yl)piperidine-4-carboxylate chemical structure, C20H23N3O3, CAS 1040653-68-6
Ethyl 1-(3-cyano-6-ethoxyquinolin-4-yl)piperidine-4-carboxylate
CAS 1040653-68-6C20H23N3O3
Ethyl 1-(3-cyanoquinolin-4-yl)piperidine-4-carboxylate chemical structure, C18H19N3O2, CAS 1021221-33-9
Ethyl 1-(3-cyanoquinolin-4-yl)piperidine-4-carboxylate
CAS 1021221-33-9C18H19N3O2
1-(3-Cyanoquinolin-4-yl)piperidine-4-carboxylic acid chemical structure, C16H15N3O2, CAS 1156272-06-8
1-(3-Cyanoquinolin-4-yl)piperidine-4-carboxylic acid
CAS 1156272-06-8C16H15N3O2
Ethyl 1-(3-cyano-6-methoxyquinolin-4-yl)piperidine-4-carboxylate chemical structure, C19H21N3O3, CAS 1207033-74-6
Ethyl 1-(3-cyano-6-methoxyquinolin-4-yl)piperidine-4-carboxylate
CAS 1207033-74-6C19H21N3O3
4-(Piperidin-1-yl)-8-(trifluoromethyl)quinoline chemical structure, C15H15F3N2, CAS 1020252-84-9
4-(Piperidin-1-yl)-8-(trifluoromethyl)quinoline
CAS 1020252-84-9C15H15F3N2
7-Chloro-8-methyl-4-(piperidin-1-yl)quinoline chemical structure, C15H17ClN2, CAS 1072944-74-1
7-Chloro-8-methyl-4-(piperidin-1-yl)quinoline
CAS 1072944-74-1C15H17ClN2