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Murcko scaffold

1-Benzyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol scaffold

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
16
With full pages
4
Scaffold SMILES

O=c1[nH]cnc2c1cnn2Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol page
Murcko scaffold O=c1[nH]cnc2c1cnn2Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Methyl 2-(1-(2-fluorobenzyl)-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-5(4H)-yl)acetate chemical structure, C15H13FN4O3, CAS 1203320-85-7
Methyl 2-(1-(2-fluorobenzyl)-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-5(4H)-yl)acetate
CAS 1203320-85-7C15H13FN4O3
5-Amino-1-benzyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one chemical structure, C12H11N5O, CAS 905244-78-2
5-Amino-1-benzyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one
CAS 905244-78-2C12H11N5O
1-Benzyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol chemical structure, C12H10N4O, CAS 35877-37-3
1-Benzyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol
CAS 35877-37-3C12H10N4O
1-((4-Chlorophenyl)methyl)-1H-pyrazolo(3,4-d)pyrimidin-4-ol chemical structure, C12H9ClN4O, CAS 612523-78-1
1-((4-Chlorophenyl)methyl)-1H-pyrazolo(3,4-d)pyrimidin-4-ol
CAS 612523-78-1C12H9ClN4O
1-(4-Methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol chemical structure, C13H12N4O, CAS 612524-10-4
1-(4-Methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol
CAS 612524-10-4C13H12N4O
1-(2-Chlorobenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol chemical structure, C12H9ClN4O, CAS 903868-98-4
1-(2-Chlorobenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol
CAS 903868-98-4C12H9ClN4O
1-[(2,4-Dichlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-ol chemical structure, C12H8Cl2N4O, CAS 125240-57-5
1-[(2,4-Dichlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-ol
CAS 125240-57-5C12H8Cl2N4O
1-(4-Methoxybenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C13H12N4O2, CAS 1021029-65-1
1-(4-Methoxybenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one
CAS 1021029-65-1C13H12N4O2
1-(4-Fluorobenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C12H9FN4O, CAS 1207042-08-7
1-(4-Fluorobenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one
CAS 1207042-08-7C12H9FN4O
1-[(2-Fluorophenyl)methyl]-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one chemical structure, C12H9FN4O, CAS 1207022-53-4
1-[(2-Fluorophenyl)methyl]-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one
CAS 1207022-53-4C12H9FN4O
1-Benzyl-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C13H12N4OS, CAS 130819-74-8
1-Benzyl-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one
CAS 130819-74-8C13H12N4OS
Ethyl 2-(2-((1-(3-chlorobenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)thio)acetamido)acetate chemical structure, C18H18ClN5O4S, CAS 1207044-23-2
Ethyl 2-(2-((1-(3-chlorobenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)thio)acetamido)acetate
CAS 1207044-23-2C18H18ClN5O4S
2-((1-(4-Fluorobenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)thio)-N-methylacetamide chemical structure, C15H14FN5O2S, CAS 1171860-07-3
2-((1-(4-Fluorobenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)thio)-N-methylacetamide
CAS 1171860-07-3C15H14FN5O2S
Methyl 2-((1-benzyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)thio)propanoate chemical structure, C16H16N4O3S, CAS 1207047-76-4
Methyl 2-((1-benzyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)thio)propanoate
CAS 1207047-76-4C16H16N4O3S
1-Benzyl-3-bromo-1H-pyrazolo[3,4-d]pyrimidin-4-ol chemical structure, C12H9BrN4O, CAS 2138303-54-3
1-Benzyl-3-bromo-1H-pyrazolo[3,4-d]pyrimidin-4-ol
CAS 2138303-54-3C12H9BrN4O
PDE2 inhibitor 4 chemical structure, C16H15F3N4O2, CAS 2055160-19-3
PDE2 inhibitor 4
CAS 2055160-19-3C16H15F3N4O2