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Murcko scaffold

Ring system with 2 rings and 18 atoms

24 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
24
With full pages
8
Scaffold SMILES

O=C(CS(=O)(=O)c1ccccc1)Nc1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CS(=O)(=O)c1ccccc1)Nc1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2,4-Dimethyl 5-[2-(4-chlorobenzenesulfonyl)acetamido]-3-methylthiophene-2,4-dicarboxylate chemical structure, C17H16ClNO7S2, CAS 380562-88-9
2,4-Dimethyl 5-[2-(4-chlorobenzenesulfonyl)acetamido]-3-methylthiophene-2,4-dicarboxylate
CAS 380562-88-9C17H16ClNO7S2
Ethyl 4,5-dimethyl-2-(2-(phenylsulfonyl)acetamido)thiophene-3-carboxylate chemical structure, C17H19NO5S2, CAS 892062-60-1
Ethyl 4,5-dimethyl-2-(2-(phenylsulfonyl)acetamido)thiophene-3-carboxylate
CAS 892062-60-1C17H19NO5S2
N-Methyl-2-(2-tosylacetamido)thiophene-3-carboxamide chemical structure, C15H16N2O4S2, CAS 895453-22-2
N-Methyl-2-(2-tosylacetamido)thiophene-3-carboxamide
CAS 895453-22-2C15H16N2O4S2
2-(2-((4-Chlorophenyl)sulfonyl)acetamido)thiophene-3-carboxamide chemical structure, C13H11ClN2O4S2, CAS 895469-16-6
2-(2-((4-Chlorophenyl)sulfonyl)acetamido)thiophene-3-carboxamide
CAS 895469-16-6C13H11ClN2O4S2
2-(2-((4-Chlorophenyl)sulfonyl)acetamido)-N-methylthiophene-3-carboxamide chemical structure, C14H13ClN2O4S2, CAS 895469-23-5
2-(2-((4-Chlorophenyl)sulfonyl)acetamido)-N-methylthiophene-3-carboxamide
CAS 895469-23-5C14H13ClN2O4S2
Methyl 2-(2-(phenylsulfonyl)acetamido)thiophene-3-carboxylate chemical structure, C14H13NO5S2, CAS 895463-24-8
Methyl 2-(2-(phenylsulfonyl)acetamido)thiophene-3-carboxylate
CAS 895463-24-8C14H13NO5S2
2-(2-((4-Fluorophenyl)sulfonyl)acetamido)thiophene-3-carboxamide chemical structure, C13H11FN2O4S2, CAS 895481-65-9
2-(2-((4-Fluorophenyl)sulfonyl)acetamido)thiophene-3-carboxamide
CAS 895481-65-9C13H11FN2O4S2
2-(2-((4-Fluorophenyl)sulfonyl)acetamido)-N-methylthiophene-3-carboxamide chemical structure, C14H13FN2O4S2, CAS 895481-73-9
2-(2-((4-Fluorophenyl)sulfonyl)acetamido)-N-methylthiophene-3-carboxamide
CAS 895481-73-9C14H13FN2O4S2
2-(Benzenesulfonyl)-N-(3-cyano-4,5-dimethylthiophen-2-yl)acetamide chemical structure, C15H14N2O3S2, CAS 896305-90-1
2-(Benzenesulfonyl)-N-(3-cyano-4,5-dimethylthiophen-2-yl)acetamide
CAS 896305-90-1C15H14N2O3S2
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-2-(4-fluorophenyl)sulfonylacetamide chemical structure, C15H13FN2O3S2, CAS 896306-06-2
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-2-(4-fluorophenyl)sulfonylacetamide
CAS 896306-06-2C15H13FN2O3S2
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-2-tosylacetamide chemical structure, C16H16N2O3S2, CAS 896306-36-8
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-2-tosylacetamide
CAS 896306-36-8C16H16N2O3S2
2-(4-Chlorophenyl)sulfonyl-N-(3-cyano-4,5-dimethylthiophen-2-yl)acetamide chemical structure, C15H13ClN2O3S2, CAS 896306-66-4
2-(4-Chlorophenyl)sulfonyl-N-(3-cyano-4,5-dimethylthiophen-2-yl)acetamide
CAS 896306-66-4C15H13ClN2O3S2
2-(2-((4-Fluorophenyl)sulfonyl)acetamido)-4,5-dimethylthiophene-3-carboxamide chemical structure, C15H15FN2O4S2, CAS 896291-16-0
2-(2-((4-Fluorophenyl)sulfonyl)acetamido)-4,5-dimethylthiophene-3-carboxamide
CAS 896291-16-0C15H15FN2O4S2
N,4,5-trimethyl-2-(2-(phenylsulfonyl)acetamido)thiophene-3-carboxamide chemical structure, C16H18N2O4S2, CAS 896300-97-3
N,4,5-trimethyl-2-(2-(phenylsulfonyl)acetamido)thiophene-3-carboxamide
CAS 896300-97-3C16H18N2O4S2
2-(2-((4-Fluorophenyl)sulfonyl)acetamido)-N,4,5-trimethylthiophene-3-carboxamide chemical structure, C16H17FN2O4S2, CAS 896301-19-2
2-(2-((4-Fluorophenyl)sulfonyl)acetamido)-N,4,5-trimethylthiophene-3-carboxamide
CAS 896301-19-2C16H17FN2O4S2
2-(2-((4-Chlorophenyl)sulfonyl)acetamido)-N,4,5-trimethylthiophene-3-carboxamide chemical structure, C16H17ClN2O4S2, CAS 896302-80-0
2-(2-((4-Chlorophenyl)sulfonyl)acetamido)-N,4,5-trimethylthiophene-3-carboxamide
CAS 896302-80-0C16H17ClN2O4S2
Methyl 4,5-dimethyl-2-(2-(phenylsulfonyl)acetamido)thiophene-3-carboxylate chemical structure, C16H17NO5S2, CAS 896616-58-3
Methyl 4,5-dimethyl-2-(2-(phenylsulfonyl)acetamido)thiophene-3-carboxylate
CAS 896616-58-3C16H17NO5S2
Methyl 2-(2-((4-fluorophenyl)sulfonyl)acetamido)-4,5-dimethylthiophene-3-carboxylate chemical structure, C16H16FNO5S2, CAS 896616-64-1
Methyl 2-(2-((4-fluorophenyl)sulfonyl)acetamido)-4,5-dimethylthiophene-3-carboxylate
CAS 896616-64-1C16H16FNO5S2
4,5-Dimethyl-2-(2-(phenylsulfonyl)acetamido)thiophene-3-carboxamide chemical structure, C15H16N2O4S2, CAS 896291-00-2
4,5-Dimethyl-2-(2-(phenylsulfonyl)acetamido)thiophene-3-carboxamide
CAS 896291-00-2C15H16N2O4S2
Ethyl 3-methyl-5-(2-(phenylsulfonyl)acetamido)thiophene-2-carboxylate chemical structure, C16H17NO5S2, CAS 895460-18-1
Ethyl 3-methyl-5-(2-(phenylsulfonyl)acetamido)thiophene-2-carboxylate
CAS 895460-18-1C16H17NO5S2
N-(3-Cyanothiophen-2-yl)-2-((4-methoxyphenyl)sulfonyl)acetamide chemical structure, C14H12N2O4S2, CAS 941908-07-2
N-(3-Cyanothiophen-2-yl)-2-((4-methoxyphenyl)sulfonyl)acetamide
CAS 941908-07-2C14H12N2O4S2
2-(2-((4-Methoxyphenyl)sulfonyl)acetamido)thiophene-3-carboxamide chemical structure, C14H14N2O5S2, CAS 941901-84-4
2-(2-((4-Methoxyphenyl)sulfonyl)acetamido)thiophene-3-carboxamide
CAS 941901-84-4C14H14N2O5S2
2-(2-((4-Methoxyphenyl)sulfonyl)acetamido)-N-methylthiophene-3-carboxamide chemical structure, C15H16N2O5S2, CAS 941951-89-9
2-(2-((4-Methoxyphenyl)sulfonyl)acetamido)-N-methylthiophene-3-carboxamide
CAS 941951-89-9C15H16N2O5S2
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-2-((4-methoxyphenyl)sulfonyl)acetamide chemical structure, C16H16N2O4S2, CAS 941951-97-9
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-2-((4-methoxyphenyl)sulfonyl)acetamide
CAS 941951-97-9C16H16N2O4S2