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Murcko scaffold

Ring system with 2 rings and 16 atoms

85 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
85
With full pages
22
Scaffold SMILES

O=C(CSc1nnn[nH]1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnn[nH]1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 85 chemicals

N-(4-Ethylphenyl)-2-[(1-methyl-1H-tetraazol-5-yl)sulfanyl]acetamide chemical structure, C12H15N5OS, CAS 306732-44-5
N-(4-Ethylphenyl)-2-[(1-methyl-1H-tetraazol-5-yl)sulfanyl]acetamide
CAS 306732-44-5C12H15N5OS
2-[(1-Methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C11H10F3N5OS, CAS 271798-73-3
2-[(1-Methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 271798-73-3C11H10F3N5OS
{5-[(4-Ethoxy-phenylcarbamoyl)-methylsulfanyl]-tetrazol-1-yl}-acetic acid chemical structure, C13H15N5O4S, CAS 433251-85-5
{5-[(4-Ethoxy-phenylcarbamoyl)-methylsulfanyl]-tetrazol-1-yl}-acetic acid
CAS 433251-85-5C13H15N5O4S
N-(4-Acetylphenyl)-2-(1-methyltetrazol-5-yl)sulfanylbutanamide chemical structure, C14H17N5O2S, CAS 496772-21-5
N-(4-Acetylphenyl)-2-(1-methyltetrazol-5-yl)sulfanylbutanamide
CAS 496772-21-5C14H17N5O2S
N-(5-Fluoro-2-methylphenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide chemical structure, C11H12FN5OS, CAS 329078-54-8
N-(5-Fluoro-2-methylphenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide
CAS 329078-54-8C11H12FN5OS
N-(3,4-Dichlorophenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide chemical structure, C10H9Cl2N5OS, CAS 329078-59-3
N-(3,4-Dichlorophenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide
CAS 329078-59-3C10H9Cl2N5OS
N-(3-Chloro-4-fluorophenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide chemical structure, C10H9ClFN5OS, CAS 329078-73-1
N-(3-Chloro-4-fluorophenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide
CAS 329078-73-1C10H9ClFN5OS
N-(2,5-Difluorophenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide chemical structure, C10H9F2N5OS, CAS 329079-75-6
N-(2,5-Difluorophenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide
CAS 329079-75-6C10H9F2N5OS
2-(1-Methyltetrazol-5-yl)sulfanyl-N-(3-nitrophenyl)acetamide chemical structure, C10H10N6O3S, CAS 299202-41-8
2-(1-Methyltetrazol-5-yl)sulfanyl-N-(3-nitrophenyl)acetamide
CAS 299202-41-8C10H10N6O3S
2-(1-Methyltetrazol-5-yl)sulfanyl-N-[4-(trifluoromethoxy)phenyl]acetamide chemical structure, C11H10F3N5O2S, CAS 212074-56-1
2-(1-Methyltetrazol-5-yl)sulfanyl-N-[4-(trifluoromethoxy)phenyl]acetamide
CAS 212074-56-1C11H10F3N5O2S
N-(4-Bromophenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide chemical structure, C10H10BrN5OS, CAS 331982-06-0
N-(4-Bromophenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide
CAS 331982-06-0C10H10BrN5OS
N-Mesityl-2-((1-methyl-1H-tetrazol-5-yl)thio)acetamide chemical structure, C13H17N5OS, CAS 300860-39-3
N-Mesityl-2-((1-methyl-1H-tetrazol-5-yl)thio)acetamide
CAS 300860-39-3C13H17N5OS
2-(1-Methyltetrazol-5-yl)sulfanyl-N-phenylacetamide chemical structure, C10H11N5OS, CAS 6045-28-9
2-(1-Methyltetrazol-5-yl)sulfanyl-N-phenylacetamide
CAS 6045-28-9C10H11N5OS
2-[5-[2-(2,4-Dimethylanilino)-2-oxoethyl]sulfanyltetrazol-1-yl]acetic acid chemical structure, C13H15N5O3S, CAS 433246-78-7
2-[5-[2-(2,4-Dimethylanilino)-2-oxoethyl]sulfanyltetrazol-1-yl]acetic acid
CAS 433246-78-7C13H15N5O3S
2-[5-[2-(2-Fluoroanilino)-2-oxoethyl]sulfanyltetrazol-1-yl]acetic acid chemical structure, C11H10FN5O3S, CAS 433317-47-6
2-[5-[2-(2-Fluoroanilino)-2-oxoethyl]sulfanyltetrazol-1-yl]acetic acid
CAS 433317-47-6C11H10FN5O3S
N-(4-Methoxyphenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide chemical structure, C11H13N5O2S, CAS 335223-24-0
N-(4-Methoxyphenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide
CAS 335223-24-0C11H13N5O2S
N-(4-Bromo-3-methylphenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide chemical structure, C11H12BrN5OS, CAS 482298-22-6
N-(4-Bromo-3-methylphenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide
CAS 482298-22-6C11H12BrN5OS
N-(4-Bromo-2-methylphenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide chemical structure, C11H12BrN5OS, CAS 329779-20-6
N-(4-Bromo-2-methylphenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]acetamide
CAS 329779-20-6C11H12BrN5OS
N-(3-Methylphenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide chemical structure, C11H13N5OS, CAS 483293-56-7
N-(3-Methylphenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide
CAS 483293-56-7C11H13N5OS
2-[2-(1-Methyl-1H-tetrazol-5-ylsulfanyl)-acetylamino]-benzoic acid methyl ester chemical structure, C12H13N5O3S, CAS 333422-85-8
2-[2-(1-Methyl-1H-tetrazol-5-ylsulfanyl)-acetylamino]-benzoic acid methyl ester
CAS 333422-85-8C12H13N5O3S
N-(2-Chlorophenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide chemical structure, C10H10ClN5OS, CAS 333422-87-0
N-(2-Chlorophenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide
CAS 333422-87-0C10H10ClN5OS
N-(2,5-Dimethoxyphenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide chemical structure, C12H15N5O3S, CAS 379710-29-9
N-(2,5-Dimethoxyphenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide
CAS 379710-29-9C12H15N5O3S
N-(3,5-Dichlorophenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide chemical structure, C10H9Cl2N5OS, CAS 452959-32-9
N-(3,5-Dichlorophenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide
CAS 452959-32-9C10H9Cl2N5OS
N-(4-Cyanophenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide chemical structure, C11H10N6OS, CAS 485374-21-8
N-(4-Cyanophenyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide
CAS 485374-21-8C11H10N6OS