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Murcko scaffold

Ring system with 2 rings and 16 atoms

213 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
213
With full pages
21
Scaffold SMILES

O=C(CSc1ncc[nH]1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ncc[nH]1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 213 chemicals

2-(1-Methylimidazol-2-yl)sulfanyl-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C13H12F3N3OS, CAS 335206-72-9
2-(1-Methylimidazol-2-yl)sulfanyl-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 335206-72-9C13H12F3N3OS
N-(3-Hydroxyphenyl)-2-(1-methylimidazol-2-yl)sulfanylacetamide chemical structure, C12H13N3O2S, CAS 381193-60-8
N-(3-Hydroxyphenyl)-2-(1-methylimidazol-2-yl)sulfanylacetamide
CAS 381193-60-8C12H13N3O2S
2-(1-Methylimidazol-2-yl)sulfanyl-N-(2-methylsulfanylphenyl)acetamide chemical structure, C13H15N3OS2, CAS 351061-86-4
2-(1-Methylimidazol-2-yl)sulfanyl-N-(2-methylsulfanylphenyl)acetamide
CAS 351061-86-4C13H15N3OS2
N-(2-Cyanophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C13H12N4OS, CAS 329079-20-1
N-(2-Cyanophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 329079-20-1C13H12N4OS
N-(4-Fluorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C12H12FN3OS, CAS 270086-74-3
N-(4-Fluorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 270086-74-3C12H12FN3OS
N-(2,3-Dimethylphenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C14H17N3OS, CAS 329080-21-9
N-(2,3-Dimethylphenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 329080-21-9C14H17N3OS
2-[(1-Methyl-1H-imidazol-2-yl)sulfanyl]-N-[4-(propan-2-yl)phenyl]acetamide chemical structure, C15H19N3OS, CAS 212074-67-4
2-[(1-Methyl-1H-imidazol-2-yl)sulfanyl]-N-[4-(propan-2-yl)phenyl]acetamide
CAS 212074-67-4C15H19N3OS
N-(3-Chloro-4-methylphenyl)-2-((1-methyl-1H-imidazol-2-yl)thio)acetamide chemical structure, C13H14ClN3OS, CAS 306732-11-6
N-(3-Chloro-4-methylphenyl)-2-((1-methyl-1H-imidazol-2-yl)thio)acetamide
CAS 306732-11-6C13H14ClN3OS
N-(2,3-Dichlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C12H11Cl2N3OS, CAS 306732-06-9
N-(2,3-Dichlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 306732-06-9C12H11Cl2N3OS
4-{2-[(1-Methyl-1H-imidazol-2-yl)sulfanyl]acetamido}benzoic acid chemical structure, C13H13N3O3S, CAS 328288-94-4
4-{2-[(1-Methyl-1H-imidazol-2-yl)sulfanyl]acetamido}benzoic acid
CAS 328288-94-4C13H13N3O3S
N-(4-Acetylphenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C14H15N3O2S, CAS 255874-94-3
N-(4-Acetylphenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 255874-94-3C14H15N3O2S
N-(3,5-Dimethylphenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C14H17N3OS, CAS 298215-48-2
N-(3,5-Dimethylphenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 298215-48-2C14H17N3OS
N-(4-Ethoxyphenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C14H17N3O2S, CAS 212074-68-5
N-(4-Ethoxyphenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 212074-68-5C14H17N3O2S
N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C13H11ClF3N3OS, CAS 329928-99-6
N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 329928-99-6C13H11ClF3N3OS
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-(1-methylimidazol-2-yl)sulfanylacetamide chemical structure, C13H11ClF3N3OS, CAS 270262-56-1
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-(1-methylimidazol-2-yl)sulfanylacetamide
CAS 270262-56-1C13H11ClF3N3OS
2-(1-Methylimidazol-2-yl)sulfanyl-N-(2-propan-2-yloxyphenyl)acetamide chemical structure, C15H19N3O2S, CAS 684237-72-7
2-(1-Methylimidazol-2-yl)sulfanyl-N-(2-propan-2-yloxyphenyl)acetamide
CAS 684237-72-7C15H19N3O2S
2-(1-Methylimidazol-2-yl)sulfanyl-N-(3-methylphenyl)acetamide chemical structure, C13H15N3OS, CAS 425646-63-5
2-(1-Methylimidazol-2-yl)sulfanyl-N-(3-methylphenyl)acetamide
CAS 425646-63-5C13H15N3OS
N-(3,4-Dichlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C12H11Cl2N3OS, CAS 303091-46-5
N-(3,4-Dichlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 303091-46-5C12H11Cl2N3OS
N-(2-Bromophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C12H12BrN3OS, CAS 457078-71-6
N-(2-Bromophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 457078-71-6C12H12BrN3OS
N-[4-Bromo-2-(trifluoromethyl)phenyl]-2-(1-methylimidazol-2-yl)sulfanylacetamide chemical structure, C13H11BrF3N3OS, CAS 351061-71-7
N-[4-Bromo-2-(trifluoromethyl)phenyl]-2-(1-methylimidazol-2-yl)sulfanylacetamide
CAS 351061-71-7C13H11BrF3N3OS
N-[3,5-Bis(trifluoromethyl)phenyl]-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C14H11F6N3OS, CAS 306732-34-3
N-[3,5-Bis(trifluoromethyl)phenyl]-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 306732-34-3C14H11F6N3OS
N-(3-Chloro-4-fluorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C12H11ClFN3OS, CAS 298215-33-5
N-(3-Chloro-4-fluorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 298215-33-5C12H11ClFN3OS
N-(4-Chlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C12H12ClN3OS, CAS 212074-51-6
N-(4-Chlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 212074-51-6C12H12ClN3OS
N-(3,5-Dichlorophenyl)-2-(1-methylimidazol-2-ylthio)acetamide chemical structure, C12H11Cl2N3OS, CAS 263016-04-2
N-(3,5-Dichlorophenyl)-2-(1-methylimidazol-2-ylthio)acetamide
CAS 263016-04-2C12H11Cl2N3OS