Murcko scaffold
Benzoic acid, 2-(2-furanylmethylene)hydrazide scaffold
86 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 86
- With full pages
- 19
Scaffold SMILES
O=C(NN=Cc1ccco1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 86 chemicals
Benzoic acid, 2-(2-furanylmethylene)hydrazide
CAS 62214-31-7C12H10N2O2
![2,4-Dihydroxybenzoic acid 2-[(5-nitro-2-furanyl)methylene]hydrazide chemical structure, C12H9N3O6, CAS 304481-57-0](/s/ZTQOQTRATCODQB-UHFFFAOYSA-N.svg)
2,4-Dihydroxybenzoic acid 2-[(5-nitro-2-furanyl)methylene]hydrazide
CAS 304481-57-0C12H9N3O6
![4-(1,1-Dimethylethyl)benzoic acid 2-[(5-methyl-2-furanyl)methylene]hydrazide chemical structure, C17H20N2O2, CAS 113906-26-6](/s/FSRNAXODRQGWDI-UHFFFAOYSA-N.svg)
4-(1,1-Dimethylethyl)benzoic acid 2-[(5-methyl-2-furanyl)methylene]hydrazide
CAS 113906-26-6C17H20N2O2
![2-Nitrobenzoic acid 2-[(5-methyl-2-furanyl)methylene]hydrazide chemical structure, C13H11N3O4, CAS 113906-28-8](/s/MJQJDDUUQWCUDQ-UHFFFAOYSA-N.svg)
2-Nitrobenzoic acid 2-[(5-methyl-2-furanyl)methylene]hydrazide
CAS 113906-28-8C13H11N3O4
![3,4,5-Triethoxy-N'-[(5-nitrofuran-2-yl)methylidene]benzohydrazide chemical structure, C18H21N3O7, CAS 380337-00-8](/s/BBTYVDGLRXUEQC-UHFFFAOYSA-N.svg)
3,4,5-Triethoxy-N'-[(5-nitrofuran-2-yl)methylidene]benzohydrazide
CAS 380337-00-8C18H21N3O7
![3-Nitro-N-[(5-nitrofuran-2-yl)methylideneamino]benzamide chemical structure, C12H8N4O6](/s/SUPOWFAECZKOCS-UHFFFAOYSA-N.svg)
3-Nitro-N-[(5-nitrofuran-2-yl)methylideneamino]benzamide
C12H8N4O6
3-Iodobenzoic acid 2-(2-furanylmethylene)hydrazide
CAS 93418-05-4C12H9IN2O2
![4-Bromo-N-[(E)-furan-2-ylmethylideneamino]benzamide chemical structure, C12H9BrN2O2, CAS 93444-96-3](/s/AUVZJZNPQFHSRR-RIYZIHGNSA-N.svg)
4-Bromo-N-[(E)-furan-2-ylmethylideneamino]benzamide
CAS 93444-96-3C12H9BrN2O2
![4-Fluoro-N-[(E)-2-furylmethyleneamino]benzamide chemical structure, C12H9FN2O2, CAS 5272-80-0](/s/LHXRWWWWTVMWDS-RIYZIHGNSA-N.svg)
4-Fluoro-N-[(E)-2-furylmethyleneamino]benzamide
CAS 5272-80-0C12H9FN2O2
![3-Iodo-N-[(E)-(5-methylfuran-2-yl)methylideneamino]benzamide chemical structure, C13H11IN2O2, CAS 303214-65-5](/s/RKKWSUPMQDQUFO-OVCLIPMQSA-N.svg)
3-Iodo-N-[(E)-(5-methylfuran-2-yl)methylideneamino]benzamide
CAS 303214-65-5C13H11IN2O2
![3-Chloro-N-[(E)-(5-methylfuran-2-yl)methylideneamino]benzamide chemical structure, C13H11ClN2O2, CAS 113906-16-4](/s/GKDLEFNBAFQSAZ-OVCLIPMQSA-N.svg)
3-Chloro-N-[(E)-(5-methylfuran-2-yl)methylideneamino]benzamide
CAS 113906-16-4C13H11ClN2O2
![2-Methyl-N'-[(5-methyl-2-furyl)methylene]benzohydrazide chemical structure, C14H14N2O2, CAS 113906-22-2](/s/FNNCFXAZALKPBW-OQLLNIDSSA-N.svg)
2-Methyl-N'-[(5-methyl-2-furyl)methylene]benzohydrazide
CAS 113906-22-2C14H14N2O2
![3-Chloro-N-[(E)-1-(furan-2-yl)ethylideneamino]benzamide chemical structure, C13H11ClN2O2, CAS 113906-39-1](/s/SDSBIXZBROTQIP-OQLLNIDSSA-N.svg)
3-Chloro-N-[(E)-1-(furan-2-yl)ethylideneamino]benzamide
CAS 113906-39-1C13H11ClN2O2
![4-Bromo-N-[(Z)-(5-iodofuran-2-yl)methylideneamino]benzamide chemical structure, C12H8BrIN2O2, CAS 5476-23-3](/s/KJVGDUPXCLFMCP-CHHVJCJISA-N.svg)
4-Bromo-N-[(Z)-(5-iodofuran-2-yl)methylideneamino]benzamide
CAS 5476-23-3C12H8BrIN2O2
![4-Chloro-N-[(E)-1-(5-methylfuran-2-yl)ethylideneamino]benzamide chemical structure, C14H13ClN2O2, CAS 339171-92-5](/s/HTGBSARXEVHDDN-MHWRWJLKSA-N.svg)
4-Chloro-N-[(E)-1-(5-methylfuran-2-yl)ethylideneamino]benzamide
CAS 339171-92-5C14H13ClN2O2
Nifuroxazide
CAS 965-52-6C12H9N3O5
![N-[(E)-Furan-2-ylmethylideneamino]benzamide chemical structure, C12H10N2O2, CAS 222851-88-9](/s/FLSCWWXUVAYOLY-UKTHLTGXSA-N.svg)
N-[(E)-Furan-2-ylmethylideneamino]benzamide
CAS 222851-88-9C12H10N2O2
![4-Chloro-2-hydroxy-N-[(E)-(5-methylfuran-2-yl)methylideneamino]benzamide chemical structure, C13H11ClN2O3, CAS 416872-94-1](/s/RGULXQDZOITCAN-VIZOYTHASA-N.svg)
4-Chloro-2-hydroxy-N-[(E)-(5-methylfuran-2-yl)methylideneamino]benzamide
CAS 416872-94-1C13H11ClN2O3
![2-Amino-N-[(Z)-(5-bromofuran-2-yl)methylideneamino]benzamide chemical structure, C12H10BrN3O2, CAS 5661-26-7](/s/KRULCESOMLJEJA-CHHVJCJISA-N.svg)
2-Amino-N-[(Z)-(5-bromofuran-2-yl)methylideneamino]benzamide
CAS 5661-26-7C12H10BrN3O2
![3,4,5-Trimethoxy-N-[(E)-(5-methylfuran-2-yl)methylideneamino]benzamide chemical structure, C16H18N2O5, CAS 329024-14-8](/s/FXXFCWSZFDVOAV-RQZCQDPDSA-N.svg)
3,4,5-Trimethoxy-N-[(E)-(5-methylfuran-2-yl)methylideneamino]benzamide
CAS 329024-14-8C16H18N2O5
![4-(Dimethylamino)-N'-[(1E)-1-(furan-2-yl)ethylidene]benzohydrazide chemical structure, C15H17N3O2, CAS 5689-61-2](/s/GUZVKVHGHDBKQW-LFIBNONCSA-N.svg)
4-(Dimethylamino)-N'-[(1E)-1-(furan-2-yl)ethylidene]benzohydrazide
CAS 5689-61-2C15H17N3O2
![N'-[(Z)-(5-Nitrofuran-2-yl)methylidene]benzohydrazide chemical structure, C12H9N3O4, CAS 28123-74-2](/s/VFOAAIIORKZVIH-JYRVWZFOSA-N.svg)
N'-[(Z)-(5-Nitrofuran-2-yl)methylidene]benzohydrazide
CAS 28123-74-2C12H9N3O4
![4-tert-Butyl-N'-[(5-nitrofuran-2-yl)methylidene]benzohydrazide chemical structure, C16H17N3O4, CAS 328921-50-2](/s/VXQOAGQOKGGJDG-LICLKQGHSA-N.svg)
4-tert-Butyl-N'-[(5-nitrofuran-2-yl)methylidene]benzohydrazide
CAS 328921-50-2C16H17N3O4
![N'-[1-(2-Furyl)ethylidene]benzohydrazide chemical structure, C13H12N2O2, CAS 113906-38-0](/s/CQGATEFROFGTCU-GXDHUFHOSA-N.svg)
N'-[1-(2-Furyl)ethylidene]benzohydrazide
CAS 113906-38-0C13H12N2O2
- 2,4-Dichlorobenzoic (furfurylidene)hydrazide107401-25-2C12H8Cl2N2O2
- N-[(E)-(5-Methylfuran-2-yl)methylideneamino]-3,5-dinitrobenzamide300406-61-5C13H10N4O6
- 4-Ethoxy-N-[(Z)-1-(furan-2-yl)ethylideneamino]benzamide113906-46-0C15H16N2O3
- (Z)-N'-(Furan-2-ylmethylene)-3,5-dinitrobenzohydrazide91330-77-7C12H8N4O6
- 3-Amino-N-[(Z)-(5-nitrofuran-2-yl)methylideneamino]benzamideC12H10N4O4
- N'-[1-(2-Furyl)ethylidene]-3,5-dihydroxybenzohydrazide304668-70-0C13H12N2O4
- 4-Chloro-N'-(2-furylmethylene)benzohydrazide93418-01-0C12H9ClN2O2
- N'-(2-Furylmethylene)-2-hydroxybenzohydrazide22596-74-3C12H10N2O3
- N'-(2-Furylmethylene)-4-nitrobenzohydrazide117824-92-7C12H9N3O4
- 4-Ethoxy-N'-({5-nitro-2-furyl}methylene)benzohydrazide303759-79-7C14H13N3O5
- 2-Bromo-N'-(2-furylmethylene)benzohydrazide93418-02-1C12H9BrN2O2
- 2-Hydroxy-N'-[(E)-(5-nitrofuran-2-yl)methylidene]benzohydrazide22604-68-8C12H9N3O5
- N'-(2-Furylmethylene)-4-hydroxybenzohydrazide100136-52-5C12H10N2O3
- Benzoic acid, 3-nitro-, (2-furanylmethylene)hydrazide113875-02-8C12H9N3O4
- (E)-5-Bromo-N'-(furan-2-ylmethylene)-2-hydroxybenzohydrazide109019-04-7C12H9BrN2O3
- N'-(2-Furylmethylene)-4-methylbenzohydrazide113906-79-9C13H12N2O2
- 2,4-Dichloro-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide100399-10-8C12H7Cl2N3O4
- 2-Chloro-N'-(2-furylmethylene)-5-iodobenzohydrazide331668-24-7C12H8ClIN2O2
- N'-[(5-Methyl-2-furyl)methylene]-3-nitrobenzohydrazide304448-36-0C13H11N3O4
- N'-[(5-Methyl-2-furyl)methylene]-4-nitrobenzohydrazide302604-63-3C13H11N3O4
- 2-Hydroxy-N-[(E)-(5-methylfuran-2-yl)methylideneamino]-3,5-di(propan-2-yl)benzamide445246-62-8C19H24N2O3
- 3-Nitro-N'-({5-nitro-2-furyl}methylene)benzohydrazide92695-66-4C12H8N4O6
- 2-Hydroxy-N'-[(5-methyl-2-furyl)methylene]benzohydrazide316138-45-1C13H12N2O3
- N'-[(5-Methyl-2-furyl)methylene]benzohydrazide113906-14-2C13H12N2O2
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C(CSc1nnc[nH]1)Nc1ccccc1](/scaffold/VJBDIQRNSVRUDP-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nnc[nH]1)Nc1ccccc165 chemicals
O=C(COc1ccccc1)Nc1nccs143 chemicals
O=C(CCc1ccco1)Nc1ccccc134 chemicals
O=C(CSc1nncs1)Nc1ccccc134 chemicals![Scaffold O=C(NN=Cc1ccccc1)c1cc[nH]n1](/scaffold/UEBQXDJERRSAMF-UHFFFAOYSA-N/structure.svg)
O=C(NN=Cc1ccccc1)c1cc[nH]n129 chemicals
O=C(CCc1ccccc1)Nc1nncs125 chemicals
S=C(NCc1ccco1)Nc1ccccc124 chemicals![Scaffold O=C(CSc1nnn[nH]1)Nc1ccccc1](/scaffold/FDRBWKCIVMSABC-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nnn[nH]1)Nc1ccccc122 chemicals![Scaffold O=C(CSc1ncc[nH]1)Nc1ccccc1](/scaffold/OMOYRSCPUXAYDW-UHFFFAOYSA-N/structure.svg)
O=C(CSc1ncc[nH]1)Nc1ccccc121 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccco121 chemicals
O=C(CCN1CCCC1)Nc1ccccc120 chemicals
O=C(NN=Cc1ccccc1)c1ccoc118 chemicals