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Murcko scaffold

4-Phenyl-2-(piperidin-4-yl)thiazole scaffold

53 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
53
With full pages
5
Scaffold SMILES

c1ccc(-c2csc(C3CCNCC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-2-(piperidin-4-yl)thiazole page
Murcko scaffold c1ccc(-c2csc(C3CCNCC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 53 chemicals

Piperidine, 1-ethyl-4-(4-phenyl-2-thiazolyl)- chemical structure, C16H20N2S, CAS 88654-25-5
Piperidine, 1-ethyl-4-(4-phenyl-2-thiazolyl)-
CAS 88654-25-5C16H20N2S
Piperidine, 4-[4-(4-methoxyphenyl)-2-thiazolyl]-1-methyl- chemical structure, C16H20N2OS, CAS 88654-24-4
Piperidine, 4-[4-(4-methoxyphenyl)-2-thiazolyl]-1-methyl-
CAS 88654-24-4C16H20N2OS
Piperidine, 1-ethyl-4-[4-(4-methoxyphenyl)-2-thiazolyl]- chemical structure, C17H22N2OS, CAS 88654-30-2
Piperidine, 1-ethyl-4-[4-(4-methoxyphenyl)-2-thiazolyl]-
CAS 88654-30-2C17H22N2OS
Piperidine, 4-[4-(4-chlorophenyl)-2-thiazolyl]-1-methyl- chemical structure, C15H17ClN2S, CAS 88654-20-0
Piperidine, 4-[4-(4-chlorophenyl)-2-thiazolyl]-1-methyl-
CAS 88654-20-0C15H17ClN2S
Piperidine, 4-[4-(3-bromophenyl)-2-thiazolyl]-1-ethyl- chemical structure, C16H19BrN2S, CAS 88654-28-8
Piperidine, 4-[4-(3-bromophenyl)-2-thiazolyl]-1-ethyl-
CAS 88654-28-8C16H19BrN2S
Piperidine, 4-[4-(3-bromophenyl)-2-thiazolyl]-1-methyl- chemical structure, C15H17BrN2S, CAS 88654-22-2
Piperidine, 4-[4-(3-bromophenyl)-2-thiazolyl]-1-methyl-
CAS 88654-22-2C15H17BrN2S
Piperidine, 1-ethyl-4-[4-(4-methylphenyl)-2-thiazolyl]- chemical structure, C17H22N2S, CAS 88654-29-9
Piperidine, 1-ethyl-4-[4-(4-methylphenyl)-2-thiazolyl]-
CAS 88654-29-9C17H22N2S
Piperidine, 4-[4-(4-bromophenyl)-2-thiazolyl]-1-ethyl- chemical structure, C16H19BrN2S, CAS 88654-27-7
Piperidine, 4-[4-(4-bromophenyl)-2-thiazolyl]-1-ethyl-
CAS 88654-27-7C16H19BrN2S
4-[2-(1-Methyl-piperidin-4-yl)-thiazol-4-yl]-benzoic acid chemical structure, C16H18N2O2S, CAS 860344-63-4
4-[2-(1-Methyl-piperidin-4-yl)-thiazol-4-yl]-benzoic acid
CAS 860344-63-4C16H18N2O2S
Piperidine, 4-[4-(3-bromophenyl)-2-thiazolyl]-1-ethyl-, hydrochloride chemical structure, C16H20BrClN2S, CAS 88654-39-1
Piperidine, 4-[4-(3-bromophenyl)-2-thiazolyl]-1-ethyl-, hydrochloride
CAS 88654-39-1C16H20BrClN2S
1-Methyl-4-(4-phenyl-1,3-thiazol-2-yl)piperidine chemical structure, C15H18N2S, CAS 88654-19-7
1-Methyl-4-(4-phenyl-1,3-thiazol-2-yl)piperidine
CAS 88654-19-7C15H18N2S
4-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-1-methylpiperidine chemical structure, C15H17BrN2S, CAS 88654-21-1
4-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-1-methylpiperidine
CAS 88654-21-1C15H17BrN2S
1-Methyl-4-[4-(4-methylphenyl)-1,3-thiazol-2-yl]piperidine chemical structure, C16H20N2S, CAS 88654-23-3
1-Methyl-4-[4-(4-methylphenyl)-1,3-thiazol-2-yl]piperidine
CAS 88654-23-3C16H20N2S
4-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-1-ethylpiperidine chemical structure, C16H19ClN2S, CAS 88654-26-6
4-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-1-ethylpiperidine
CAS 88654-26-6C16H19ClN2S
4-(4-Phenyl-1,3-thiazol-2-yl)-1-(propan-2-yl)piperidine chemical structure, C17H22N2S, CAS 926890-75-7
4-(4-Phenyl-1,3-thiazol-2-yl)-1-(propan-2-yl)piperidine
CAS 926890-75-7C17H22N2S
4-Phenyl-2-(piperidin-4-yl)thiazole chemical structure, C14H16N2S, CAS 887624-98-8
4-Phenyl-2-(piperidin-4-yl)thiazole
CAS 887624-98-8C14H16N2S
4-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]piperidine chemical structure, C14H15FN2S, CAS 887625-38-9
4-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]piperidine
CAS 887625-38-9C14H15FN2S
4-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]piperidine chemical structure, C14H15ClN2S, CAS 927020-17-5
4-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]piperidine
CAS 927020-17-5C14H15ClN2S
4-(4-Phenyl-1,3-thiazol-2-yl)piperidine hydrochloride chemical structure, C14H17ClN2S, CAS 1205636-88-9
4-(4-Phenyl-1,3-thiazol-2-yl)piperidine hydrochloride
CAS 1205636-88-9C14H17ClN2S
4-(4-Phenyl-1,3-thiazol-2-yl)piperidine dihydrochloride chemical structure, C14H18Cl2N2S, CAS 887624-97-7
4-(4-Phenyl-1,3-thiazol-2-yl)piperidine dihydrochloride
CAS 887624-97-7C14H18Cl2N2S
4-[4-(4-Chloro-3-nitrophenyl)-1,3-thiazol-2-yl]piperidine chemical structure, C14H14ClN3O2S, CAS 1216398-85-4
4-[4-(4-Chloro-3-nitrophenyl)-1,3-thiazol-2-yl]piperidine
CAS 1216398-85-4C14H14ClN3O2S
1-Ethyl-4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperidine--hydrogen bromide (1/1) chemical structure, C17H23BrN2OS, CAS 88654-53-9
1-Ethyl-4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperidine--hydrogen bromide (1/1)
CAS 88654-53-9C17H23BrN2OS
4-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-1-methylpiperidine--hydrogen bromide (1/1) chemical structure, C16H21BrN2OS, CAS 88654-47-1
4-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-1-methylpiperidine--hydrogen bromide (1/1)
CAS 88654-47-1C16H21BrN2OS
4-(5-Methyl-4-phenyl-2-thiazolyl)piperidine chemical structure, C15H18N2S, CAS 927020-18-6
4-(5-Methyl-4-phenyl-2-thiazolyl)piperidine
CAS 927020-18-6C15H18N2S