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Murcko scaffold

Ring system with 3 rings and 21 atoms

33 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
33
With full pages
4
Scaffold SMILES

O=S(=O)(Nc1nc(-c2ccccc2)cs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1nc(-c2ccccc2)cs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

4-Amino-N-(4-phenyl-1,3-thiazol-2-yl)benzenesulfonamide chemical structure, C15H13N3O2S2, CAS 37615-03-5
4-Amino-N-(4-phenyl-1,3-thiazol-2-yl)benzenesulfonamide
CAS 37615-03-5C15H13N3O2S2
4-Methyl-N-(4-phenyl-1,3-thiazol-2-yl)benzenesulfonamide chemical structure, C16H14N2O2S2, CAS 174081-07-3
4-Methyl-N-(4-phenyl-1,3-thiazol-2-yl)benzenesulfonamide
CAS 174081-07-3C16H14N2O2S2
N-(5-Ethyl-4-phenyl-1,3-thiazol-2-yl)benzenesulfonamide chemical structure, C17H16N2O2S2, CAS 600130-03-8
N-(5-Ethyl-4-phenyl-1,3-thiazol-2-yl)benzenesulfonamide
CAS 600130-03-8C17H16N2O2S2
4-Methyl-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzenesulfonamide chemical structure, C17H16N2O2S2, CAS 199601-87-1
4-Methyl-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzenesulfonamide
CAS 199601-87-1C17H16N2O2S2
4-Chloro-N-(5-methyl-4-(p-tolyl)thiazol-2-yl)benzenesulfonamide chemical structure, C17H15ClN2O2S2, CAS 329226-85-9
4-Chloro-N-(5-methyl-4-(p-tolyl)thiazol-2-yl)benzenesulfonamide
CAS 329226-85-9C17H15ClN2O2S2
N-[4-(4-Bromophenyl)-3-(prop-2-en-1-yl)-2,3-dihydro-1,3-thiazol-2-ylidene]benzenesulfonamide chemical structure, C18H15BrN2O2S2, CAS 526190-10-3
N-[4-(4-Bromophenyl)-3-(prop-2-en-1-yl)-2,3-dihydro-1,3-thiazol-2-ylidene]benzenesulfonamide
CAS 526190-10-3C18H15BrN2O2S2
N-[4-[(5-Ethyl-4-phenyl-1,3-thiazol-2-yl)sulfamoyl]phenyl]acetamide chemical structure, C19H19N3O3S2, CAS 600130-59-4
N-[4-[(5-Ethyl-4-phenyl-1,3-thiazol-2-yl)sulfamoyl]phenyl]acetamide
CAS 600130-59-4C19H19N3O3S2
Ethyl 2-(2-{[(4-chlorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)benzenecarboxylate chemical structure, C18H15ClN2O4S2, CAS 250713-81-6
Ethyl 2-(2-{[(4-chlorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)benzenecarboxylate
CAS 250713-81-6C18H15ClN2O4S2
cdDHQD-IN-1 chemical structure, C15H10Cl2N2O2S2, CAS 544431-43-8
cdDHQD-IN-1
CAS 544431-43-8C15H10Cl2N2O2S2
3-Chloro-N-(4-phenyl-2-thiazolyl)benzenesulfonamide chemical structure, C15H11ClN2O2S2, CAS 333436-39-8
3-Chloro-N-(4-phenyl-2-thiazolyl)benzenesulfonamide
CAS 333436-39-8C15H11ClN2O2S2
Benzenesulfonamide, 4-chloro-N-[4-(4-fluorophenyl)-2-thiazolyl]- chemical structure, C15H10ClFN2O2S2, CAS 61383-86-6
Benzenesulfonamide, 4-chloro-N-[4-(4-fluorophenyl)-2-thiazolyl]-
CAS 61383-86-6C15H10ClFN2O2S2
N-[4-(2,4-Dimethylphenyl)-1,3-thiazol-2-yl]benzenesulfonamide chemical structure, C17H16N2O2S2, CAS 544410-53-9
N-[4-(2,4-Dimethylphenyl)-1,3-thiazol-2-yl]benzenesulfonamide
CAS 544410-53-9C17H16N2O2S2
3,4-Dimethoxy-N-(4-(3-nitrophenyl)-2-thiazolyl)benzenesulfonamide chemical structure, C17H15N3O6S2, CAS 199666-03-0
3,4-Dimethoxy-N-(4-(3-nitrophenyl)-2-thiazolyl)benzenesulfonamide
CAS 199666-03-0C17H15N3O6S2
N-[4-(4-Bromophenyl)-3-ethyl-1,3-thiazol-2-ylidene]benzenesulfonamide chemical structure, C17H15BrN2O2S2, CAS 618421-38-8
N-[4-(4-Bromophenyl)-3-ethyl-1,3-thiazol-2-ylidene]benzenesulfonamide
CAS 618421-38-8C17H15BrN2O2S2
N-[(2Z)-4-(4-Bromophenyl)-3-(prop-2-en-1-yl)-1,3-thiazol-2(3H)-ylidene]benzenesulfonamide chemical structure, C18H15BrN2O2S2
N-[(2Z)-4-(4-Bromophenyl)-3-(prop-2-en-1-yl)-1,3-thiazol-2(3H)-ylidene]benzenesulfonamide
C18H15BrN2O2S2
N-[(2Z)-4-(4-Bromophenyl)-3-(3-methoxypropyl)-1,3-thiazol-2(3H)-ylidene]benzenesulfonamide chemical structure, C19H19BrN2O3S2, CAS 618421-62-8
N-[(2Z)-4-(4-Bromophenyl)-3-(3-methoxypropyl)-1,3-thiazol-2(3H)-ylidene]benzenesulfonamide
CAS 618421-62-8C19H19BrN2O3S2
N-[4-(2-Chlorophenyl)-1,3-thiazol-2-yl]-4-propylbenzenesulfonamide chemical structure, C18H17ClN2O2S2, CAS 376349-32-5
N-[4-(2-Chlorophenyl)-1,3-thiazol-2-yl]-4-propylbenzenesulfonamide
CAS 376349-32-5C18H17ClN2O2S2
N-[4-(4-Chloro-phenyl)-thiazol-2-yl]-4-methyl-benzenesulfonamide chemical structure, C16H13ClN2O2S2, CAS 199601-86-0
N-[4-(4-Chloro-phenyl)-thiazol-2-yl]-4-methyl-benzenesulfonamide
CAS 199601-86-0C16H13ClN2O2S2
4-Amino-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide chemical structure, C16H15N3O3S2, CAS 77925-50-9
4-Amino-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide
CAS 77925-50-9C16H15N3O3S2
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-nitrobenzenesulfonamide chemical structure, C15H10ClN3O4S2, CAS 477515-79-0
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-3-nitrobenzenesulfonamide
CAS 477515-79-0C15H10ClN3O4S2
N-{4-[4-(3-Nitro-phenyl)-thiazol-2-ylsulphamoyl]-phenyl}-acetamide chemical structure, C17H14N4O5S2, CAS 199602-13-6
N-{4-[4-(3-Nitro-phenyl)-thiazol-2-ylsulphamoyl]-phenyl}-acetamide
CAS 199602-13-6C17H14N4O5S2
Sulfaphenylthiazole sodium chemical structure, C15H12N3NaO2S2, CAS 63979-88-4
Sulfaphenylthiazole sodium
CAS 63979-88-4C15H12N3NaO2S2
3-Chloro-N-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide chemical structure, C15H10Cl2N2O2S2, CAS 1088177-95-0
3-Chloro-N-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide
CAS 1088177-95-0C15H10Cl2N2O2S2
Benzenesulfonamide, 4-amino-N-[4-(4-hydroxyphenyl)-2-thiazolyl]- chemical structure, C15H13N3O3S2, CAS 1352305-60-2
Benzenesulfonamide, 4-amino-N-[4-(4-hydroxyphenyl)-2-thiazolyl]-
CAS 1352305-60-2C15H13N3O3S2