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Murcko scaffold

5-Oxo-N,1-diphenylpyrrolidine-3-carboxamide scaffold

501 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
501
With full pages
49
Scaffold SMILES

O=C(Nc1ccccc1)C1CC(=O)N(c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Oxo-N,1-diphenylpyrrolidine-3-carboxamide page
Murcko scaffold O=C(Nc1ccccc1)C1CC(=O)N(c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 501 chemicals

2-[[(5-Oxo-1-phenylpyrrolidin-3-yl)carbonyl]amino]benzoic acid chemical structure, C18H16N2O4, CAS 39630-02-9
2-[[(5-Oxo-1-phenylpyrrolidin-3-yl)carbonyl]amino]benzoic acid
CAS 39630-02-9C18H16N2O4
N-(2((Hydroxyamino)carbonyl)phenyl)-5-oxo-1-phenyl-3-pyrrolidinecarboxamide chemical structure, C18H17N3O4, CAS 39630-03-0
N-(2((Hydroxyamino)carbonyl)phenyl)-5-oxo-1-phenyl-3-pyrrolidinecarboxamide
CAS 39630-03-0C18H17N3O4
N-(o-Carboxyphenyl)-2-oxo-1-phenyl-4-pyrrolidinecarboxamide chemical structure, C19H18N2O4, CAS 39630-04-1
N-(o-Carboxyphenyl)-2-oxo-1-phenyl-4-pyrrolidinecarboxamide
CAS 39630-04-1C19H18N2O4
N-(2-(((1,1-Dimethylethyl)amino)carbonyl)phenyl)-5-oxo-1-phenyl-3-pyrrolidinecarboxamide chemical structure, C22H25N3O3, CAS 39630-07-4
N-(2-(((1,1-Dimethylethyl)amino)carbonyl)phenyl)-5-oxo-1-phenyl-3-pyrrolidinecarboxamide
CAS 39630-07-4C22H25N3O3
N-(3-Chlorophenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide chemical structure, C17H15ClN2O2, CAS 312502-73-1
N-(3-Chlorophenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide
CAS 312502-73-1C17H15ClN2O2
N-(2-Fluorophenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide chemical structure, C17H15FN2O2, CAS 294873-71-5
N-(2-Fluorophenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide
CAS 294873-71-5C17H15FN2O2
N-(5-Chloro-2-hydroxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide chemical structure, C17H15ClN2O3, CAS 361369-00-8
N-(5-Chloro-2-hydroxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide
CAS 361369-00-8C17H15ClN2O3
N-(3-Hydroxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide chemical structure, C17H16N2O3, CAS 352330-53-1
N-(3-Hydroxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide
CAS 352330-53-1C17H16N2O3
N-(2,5-Dimethylphenyl)-1-(4-methylphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C20H22N2O2, CAS 339239-53-1
N-(2,5-Dimethylphenyl)-1-(4-methylphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 339239-53-1C20H22N2O2
N-(3,5-Dichlorophenyl)-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H13Cl2FN2O2, CAS 405276-83-7
N-(3,5-Dichlorophenyl)-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide
CAS 405276-83-7C17H13Cl2FN2O2
1-(3-Chloro-4-methylphenyl)-N-(2-ethoxyphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C20H21ClN2O3, CAS 446053-88-9
1-(3-Chloro-4-methylphenyl)-N-(2-ethoxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 446053-88-9C20H21ClN2O3
N-(4-Ethoxyphenyl)-1-(4-ethylphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C21H24N2O3, CAS 311315-99-8
N-(4-Ethoxyphenyl)-1-(4-ethylphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 311315-99-8C21H24N2O3
Benzoic acid, 4-[1-(4-methylphenyl)-5-oxo-3-pyrrolidinylcarbonylamino]-, ethyl ester chemical structure, C21H22N2O4, CAS 311328-92-4
Benzoic acid, 4-[1-(4-methylphenyl)-5-oxo-3-pyrrolidinylcarbonylamino]-, ethyl ester
CAS 311328-92-4C21H22N2O4
1-(4-Bromophenyl)-N-(3-nitrophenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H14BrN3O4, CAS 302560-54-9
1-(4-Bromophenyl)-N-(3-nitrophenyl)-5-oxopyrrolidine-3-carboxamide
CAS 302560-54-9C17H14BrN3O4
N-(2,4-Dimethoxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide chemical structure, C19H20N2O4, CAS 302560-02-7
N-(2,4-Dimethoxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide
CAS 302560-02-7C19H20N2O4
N-(2-Methoxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide chemical structure, C18H18N2O3, CAS 302559-98-4
N-(2-Methoxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide
CAS 302559-98-4C18H18N2O3
1-(4-Chlorophenyl)-5-oxo-N-(2,4,6-trimethylphenyl)pyrrolidine-3-carboxamide chemical structure, C20H21ClN2O2, CAS 302560-43-6
1-(4-Chlorophenyl)-5-oxo-N-(2,4,6-trimethylphenyl)pyrrolidine-3-carboxamide
CAS 302560-43-6C20H21ClN2O2
1-(4-Chlorophenyl)-N-(2-methylphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C18H17ClN2O2, CAS 339011-27-7
1-(4-Chlorophenyl)-N-(2-methylphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 339011-27-7C18H17ClN2O2
Ethyl 4-({[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]carbonyl}amino)benzoate chemical structure, C20H19ClN2O4, CAS 328090-80-8
Ethyl 4-({[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]carbonyl}amino)benzoate
CAS 328090-80-8C20H19ClN2O4
Ethyl 4-[[1-(2,5-dimethylphenyl)-5-oxopyrrolidine-3-carbonyl]amino]benzoate chemical structure, C22H24N2O4, CAS 296796-80-0
Ethyl 4-[[1-(2,5-dimethylphenyl)-5-oxopyrrolidine-3-carbonyl]amino]benzoate
CAS 296796-80-0C22H24N2O4
N-(4-Butoxyphenyl)-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C21H23FN2O3, CAS 331759-13-8
N-(4-Butoxyphenyl)-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide
CAS 331759-13-8C21H23FN2O3
1-(4-Bromophenyl)-N-(3-chloro-2-methylphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C18H16BrClN2O2, CAS 331759-40-1
1-(4-Bromophenyl)-N-(3-chloro-2-methylphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 331759-40-1C18H16BrClN2O2
N-(3-Fluorophenyl)-1-(4-methylphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C18H17FN2O2, CAS 331759-33-2
N-(3-Fluorophenyl)-1-(4-methylphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 331759-33-2C18H17FN2O2
1-(4-Bromophenyl)-N-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C17H14BrFN2O2, CAS 303067-02-9
1-(4-Bromophenyl)-N-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide
CAS 303067-02-9C17H14BrFN2O2