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Murcko scaffold

Ring system with 3 rings and 19 atoms

51 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
51
With full pages
25
Scaffold SMILES

c1ccc(CSc2nnc(-c3cccnc3)[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CSc2nnc(-c3cccnc3)[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 51 chemicals

3-((2-Methylbenzyl)thio)-5-(3-pyridinyl)-4H-1,2,4-triazol-4-amine chemical structure, C15H15N5S, CAS 578754-00-4
3-((2-Methylbenzyl)thio)-5-(3-pyridinyl)-4H-1,2,4-triazol-4-amine
CAS 578754-00-4C15H15N5S
3-[(2,5-Dimethylphenyl)methylthio]-5-(3-pyridyl)-1,2,4-triazole-4-ylamine chemical structure, C16H17N5S, CAS 578760-87-9
3-[(2,5-Dimethylphenyl)methylthio]-5-(3-pyridyl)-1,2,4-triazole-4-ylamine
CAS 578760-87-9C16H17N5S
3-(Benzylsulfanyl)-5-pyridin-3-yl-4H-1,2,4-triazol-4-amine chemical structure, C14H13N5S, CAS 332943-03-0
3-(Benzylsulfanyl)-5-pyridin-3-yl-4H-1,2,4-triazol-4-amine
CAS 332943-03-0C14H13N5S
3-[5-(Benzylsulfanyl)-4-ethyl-4H-1,2,4-triazol-3-yl]pyridine chemical structure, C16H16N4S, CAS 333331-33-2
3-[5-(Benzylsulfanyl)-4-ethyl-4H-1,2,4-triazol-3-yl]pyridine
CAS 333331-33-2C16H16N4S
3-[(2-Chlorophenyl)methylthio]-4-methyl-5-(3-pyridyl)-1,2,4-triazole chemical structure, C15H13ClN4S, CAS 482637-93-4
3-[(2-Chlorophenyl)methylthio]-4-methyl-5-(3-pyridyl)-1,2,4-triazole
CAS 482637-93-4C15H13ClN4S
3-(4-Methyl-5-((4-nitrobenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C15H13N5O2S, CAS 496777-06-1
3-(4-Methyl-5-((4-nitrobenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine
CAS 496777-06-1C15H13N5O2S
3-((2-Fluorobenzyl)thio)-5-(3-pyridinyl)-4H-1,2,4-triazol-4-amine chemical structure, C14H12FN5S, CAS 675190-72-4
3-((2-Fluorobenzyl)thio)-5-(3-pyridinyl)-4H-1,2,4-triazol-4-amine
CAS 675190-72-4C14H12FN5S
3-(4-Ethyl-5-((4-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C17H18N4S, CAS 618426-48-5
3-(4-Ethyl-5-((4-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine
CAS 618426-48-5C17H18N4S
3-(5-((2-Chloro-6-fluorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C16H14ClFN4S, CAS 618426-54-3
3-(5-((2-Chloro-6-fluorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)pyridine
CAS 618426-54-3C16H14ClFN4S
3-[(6-Chloro-2-fluorophenyl)methylthio]-5-(3-pyridyl)-1,2,4-triazole-4-ylamine chemical structure, C14H11ClFN5S, CAS 676338-95-7
3-[(6-Chloro-2-fluorophenyl)methylthio]-5-(3-pyridyl)-1,2,4-triazole-4-ylamine
CAS 676338-95-7C14H11ClFN5S
3-[(3-Fluorophenyl)methylsulfanyl]-5-pyridin-3-yl-1,2,4-triazol-4-amine chemical structure, C14H12FN5S, CAS 675190-60-0
3-[(3-Fluorophenyl)methylsulfanyl]-5-pyridin-3-yl-1,2,4-triazol-4-amine
CAS 675190-60-0C14H12FN5S
3-(4-Methyl-benzylsulfanyl)-5-pyridin-3-yl-[1,2,4]triazol-4-ylamine chemical structure, C15H15N5S, CAS 675121-08-1
3-(4-Methyl-benzylsulfanyl)-5-pyridin-3-yl-[1,2,4]triazol-4-ylamine
CAS 675121-08-1C15H15N5S
3-(4-Ethyl-5-((3-fluorobenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C16H15FN4S, CAS 618416-12-9
3-(4-Ethyl-5-((3-fluorobenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine
CAS 618416-12-9C16H15FN4S
3-(5-((3-Chlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C16H15ClN4S, CAS 618426-63-4
3-(5-((3-Chlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)pyridine
CAS 618426-63-4C16H15ClN4S
3-(5-((2-Fluorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C15H13FN4S, CAS 676248-92-3
3-(5-((2-Fluorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)pyridine
CAS 676248-92-3C15H13FN4S
3-[(3-Chlorophenyl)methylthio]-5-(3-pyridyl)-1,2,4-triazole-4-ylamine chemical structure, C14H12ClN5S, CAS 676248-03-6
3-[(3-Chlorophenyl)methylthio]-5-(3-pyridyl)-1,2,4-triazole-4-ylamine
CAS 676248-03-6C14H12ClN5S
3-(5-((3-Fluorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C15H13FN4S, CAS 676247-94-2
3-(5-((3-Fluorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)pyridine
CAS 676247-94-2C15H13FN4S
3-(4-Methyl-5-{[(4-methylphenyl)methyl]sulfanyl}-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C16H16N4S, CAS 577766-42-8
3-(4-Methyl-5-{[(4-methylphenyl)methyl]sulfanyl}-4H-1,2,4-triazol-3-yl)pyridine
CAS 577766-42-8C16H16N4S
3-(5-{[(2-Chloro-6-fluorophenyl)methyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C15H12ClFN4S, CAS 577769-10-9
3-(5-{[(2-Chloro-6-fluorophenyl)methyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)pyridine
CAS 577769-10-9C15H12ClFN4S
3-[(4-Methoxyphenyl)methylsulfanyl]-5-pyridin-3-yl-1,2,4-triazol-4-amine chemical structure, C15H15N5OS, CAS 573937-82-3
3-[(4-Methoxyphenyl)methylsulfanyl]-5-pyridin-3-yl-1,2,4-triazol-4-amine
CAS 573937-82-3C15H15N5OS
3-(4-Methyl-5-((2-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C16H16N4S, CAS 573938-37-1
3-(4-Methyl-5-((2-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine
CAS 573938-37-1C16H16N4S
3-(5-((4-Fluorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C15H13FN4S, CAS 577996-95-3
3-(5-((4-Fluorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)pyridine
CAS 577996-95-3C15H13FN4S
3-[4-Methyl-5-[(3-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine chemical structure, C16H16N4S, CAS 578749-38-9
3-[4-Methyl-5-[(3-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine
CAS 578749-38-9C16H16N4S
3-((4-Fluorobenzyl)thio)-5-(3-pyridinyl)-4H-1,2,4-triazol-4-amine chemical structure, C14H12FN5S, CAS 578758-14-2
3-((4-Fluorobenzyl)thio)-5-(3-pyridinyl)-4H-1,2,4-triazol-4-amine
CAS 578758-14-2C14H12FN5S