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Murcko scaffold

N-(4-Phenyl-thiazol-2-yl)-benzamide scaffold

1,118 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
1,118
With full pages
31
Scaffold SMILES

O=C(Nc1nc(-c2ccccc2)cs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(4-Phenyl-thiazol-2-yl)-benzamide page
Murcko scaffold O=C(Nc1nc(-c2ccccc2)cs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,118 chemicals

N-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-2-methylbenzamide chemical structure, C17H13BrN2OS, CAS 314291-74-2
N-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-2-methylbenzamide
CAS 314291-74-2C17H13BrN2OS
4-Methyl-N-(4-phenyl-2-thiazolyl)benzamide chemical structure, C17H14N2OS, CAS 87614-00-4
4-Methyl-N-(4-phenyl-2-thiazolyl)benzamide
CAS 87614-00-4C17H14N2OS
4-Methyl-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C18H16N2OS, CAS 103966-02-5
4-Methyl-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide
CAS 103966-02-5C18H16N2OS
4-Fluoro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide chemical structure, C16H11FN2OS, CAS 325471-34-9
4-Fluoro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
CAS 325471-34-9C16H11FN2OS
N-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]-2-nitrobenzamide chemical structure, C17H13N3O3S, CAS 312751-46-5
N-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]-2-nitrobenzamide
CAS 312751-46-5C17H13N3O3S
2,4-Dichloro-N-(4-phenyl-thiazol-2-yl)-benzamide chemical structure, C16H10Cl2N2OS, CAS 5307-12-0
2,4-Dichloro-N-(4-phenyl-thiazol-2-yl)-benzamide
CAS 5307-12-0C16H10Cl2N2OS
4-Fluoro-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C16H10FN3O3S, CAS 328539-65-7
4-Fluoro-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzamide
CAS 328539-65-7C16H10FN3O3S
4-Methoxy-N-(4-phenyl-2-thiazolyl)benzamide chemical structure, C17H14N2O2S, CAS 15850-34-7
4-Methoxy-N-(4-phenyl-2-thiazolyl)benzamide
CAS 15850-34-7C17H14N2O2S
3-Nitro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide chemical structure, C16H11N3O3S, CAS 299422-41-6
3-Nitro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
CAS 299422-41-6C16H11N3O3S
N-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C17H14N2OS, CAS 103966-01-4
N-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]benzamide
CAS 103966-01-4C17H14N2OS
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C16H11ClN2OS, CAS 87637-30-7
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]benzamide
CAS 87637-30-7C16H11ClN2OS
N-[4-(2,4-Difluorophenyl)-1,3-thiazol-2-yl]-4-methylbenzamide chemical structure, C17H12F2N2OS, CAS 330465-54-8
N-[4-(2,4-Difluorophenyl)-1,3-thiazol-2-yl]-4-methylbenzamide
CAS 330465-54-8C17H12F2N2OS
3,4-Dichloro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide chemical structure, C16H10Cl2N2OS, CAS 284489-34-5
3,4-Dichloro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
CAS 284489-34-5C16H10Cl2N2OS
4-Chloro-N-(4-phenyl-thiazol-2-yl)-benzamide chemical structure, C16H11ClN2OS, CAS 103966-00-3
4-Chloro-N-(4-phenyl-thiazol-2-yl)-benzamide
CAS 103966-00-3C16H11ClN2OS
4-Fluoro-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C17H13FN2OS, CAS 308293-47-2
4-Fluoro-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide
CAS 308293-47-2C17H13FN2OS
4-Methyl-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C17H13N3O3S, CAS 307533-45-5
4-Methyl-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzamide
CAS 307533-45-5C17H13N3O3S
N-[4-(4-Methoxy-3-methylphenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C18H16N2O2S, CAS 317853-95-5
N-[4-(4-Methoxy-3-methylphenyl)-1,3-thiazol-2-yl]benzamide
CAS 317853-95-5C18H16N2O2S
3-Methyl-N-(4-phenyl-1,3-thiazol-2-yl)benzamide chemical structure, C17H14N2OS, CAS 205928-33-2
3-Methyl-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
CAS 205928-33-2C17H14N2OS
4-Nitro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide chemical structure, C16H11N3O3S, CAS 15850-23-4
4-Nitro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
CAS 15850-23-4C16H11N3O3S
N-(4-(4-Cyanophenyl)thiazol-2-yl)-4-methylbenzamide chemical structure, C18H13N3OS, CAS 303797-02-6
N-(4-(4-Cyanophenyl)thiazol-2-yl)-4-methylbenzamide
CAS 303797-02-6C18H13N3OS
N-[4-(4-Ethylphenyl)-1,3-thiazol-2-yl]-3-methoxybenzamide chemical structure, C19H18N2O2S, CAS 313366-44-8
N-[4-(4-Ethylphenyl)-1,3-thiazol-2-yl]-3-methoxybenzamide
CAS 313366-44-8C19H18N2O2S
2-Fluoro-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C17H13FN2OS, CAS 313507-83-4
2-Fluoro-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide
CAS 313507-83-4C17H13FN2OS
N-(4-(4-Cyanophenyl)thiazol-2-yl)-4-methoxybenzamide chemical structure, C18H13N3O2S, CAS 307510-53-8
N-(4-(4-Cyanophenyl)thiazol-2-yl)-4-methoxybenzamide
CAS 307510-53-8C18H13N3O2S
4-Chloro-N-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]benzamide chemical structure, C17H10ClN3OS, CAS 307510-54-9
4-Chloro-N-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]benzamide
CAS 307510-54-9C17H10ClN3OS